RESUMO
The authors studied the effects of a combined oestrogenprogestogen treatment on the natural history of mammary tumours during a maximum period of seven and a half years. The group consisted of 135 patients divided into two on an age basis, sixty-six women still menstruating, and sixty-nine menopausal. A statistical study has shown that there is no significant difference between the treated and non-treated groups in the two groups of women studied. One can therefore deduce that the treatment has no effect on the evolution of mammary tumours whatever the age of the patient.
PIP: A group of 135 women, with breast cancer, 66 still menstruating and 69 menopausal, were treated with a combined progestogen-estrogen for a maximum of 7 1/2 years to prevent metastasis. Previous studies indicated excellent results in the short-term effect of such treatment. This study, however, showed that the evolution and recurrence is identical in those women treated and those in the control group. The conclusion was that the combination has no effect on the metastasis of breast cancers.
