[Effect of water on silica gel adsorption of blood plasma components].

In this work, the study of properties of silica gel as an adsorbent for plasmasorption has been performed. Investigations have been realized of the effect of silica gel preliminary treatment conditions and a period of plasma with silica gel contact on plasmasorption characteristics of human blood plasma components, such as protein, triglycerides, cholesterol (high-density and low-density one). The results obtained can be used for variation of silica gel adsorption properties, in situ at the adsorbent preparation process. For explanation of the experimental concentration and kinetic (temporal) characteristics of plasmasorption, the model of silica gel grains charging at the hydration was used.

[Oxidation of low density lipoproteins in the presence of silica gel treated with fullerene]. / Okislenie lipoproteinov nizkoi plotnosti v prisutstvii silikagelia, obratannogo fullerenom.

This study estimated the effects of low density lipoprotein (LDL) oxidation in the presence of fullerene silicagel in comparison with ions of Cu+2 in the wide region of oxidation times and reagent concentrations. Investigation is directed to reveal the reagent parameters, that promote to increase the oxidation rate of the LDL solution. It revealed only qualitative coincidence of the LDL oxidation kinetics in the presence as Cu+2 as fullerene, that indicated on the identity of the oxidation mechanism in both cases. At the same time the revealed quantitative difference between the oxidation process parameters are interpreted in the terms of oxidation potential and the electron affinity that characterize the reagent activity in the reaction accompanied by the electron transfer. The good correlation between above mentioned parameters and the oxidation rate of the aqueous LDL solution is observed: its increasing takes place at the increase of the electron affinity or at the decrease of the oxidation potential.