RESUMO
We present a systematic density functional theory study to determine the electronic structure of bending 2H-MoS2 layers up to 75° using information from in-situ nanoindentation TEM observations. The results from HOMO/LUMO and density of states plots indicate a metallic transition from the typical semiconducting phase, near Fermi energy level (EF) as a function of bending, which can mainly occur due to bending curvatures inducing a stretching and contracting of sulfur-sulfur chemical bonds located mostly over basal (001)-plane; furthermore, molybdenum ions play a major role in such transitions due to reallocation of their metallic d-character orbitals and the creation of "free electrons", possibly having an overlap between Mo-dx2-y2 and Modz2 orbitals. This research on the metallic transition of 2H-MoS2 allows us to understand the high catalytic activity for MoS2 nanostructures as extensively reported in the literature.
RESUMO
INTRODUCTION: Basal cell nevus syndrome (BCNS), also known as Gorlin-Goltz syndrome, comprises five main pathological features: nevoid basal cell carcinomas, keratocystic odontogenic tumors, congenital skeletal anomalies, calcification of the falx cerebri, and point skin depressions on the palms and/or soles. The disease exhibits a dominant autosomal hereditary trait, with implication of the human homologue of the Drosophila segment polarity Patched (PTCH) gene. BCNS is diagnosed on the basis of clinical and radiological criteria and can be confirmed by genetic study. The patient prognosis is very good, with normal life expectancy in most cases. METHODS: The present study reports two cases of BCNS with the presence of maxillo-mandibular keratocystic odontogenic tumors. RESULTS: One case was diagnosed according to clinical criteria, while the other required genetic confirmation that revealed a germ line mutation in exon 17 (c.2868delC), not previously described in the databases, which was considered to be responsible for the disease.
Assuntos
Síndrome do Nevo Basocelular/genética , Síndrome do Nevo Basocelular/patologia , Neoplasias Maxilomandibulares/genética , Neoplasias Maxilomandibulares/patologia , Criança , Cromossomos Humanos Par 9 , Códon sem Sentido , Feminino , Mutação da Fase de Leitura , Mutação em Linhagem Germinativa , Humanos , Masculino , Cistos Odontogênicos/patologia , Receptores Patched , Receptor Patched-1 , Receptores de Superfície Celular/genéticaAssuntos
Neoplasias Musculares/diagnóstico , Sarcoma de Células Claras/diagnóstico , Músculo Temporal/patologia , Diagnóstico Diferencial , Fáscia/patologia , Rearranjo Gênico/genética , Humanos , Hibridização in Situ Fluorescente , Imageamento por Ressonância Magnética , Neoplasias Musculares/genética , Proteína EWS de Ligação a RNA/análise , Proteína EWS de Ligação a RNA/genética , Sarcoma de Células Claras/genéticaRESUMO
INTRODUCTION: Orbital floor fractures are usually the result of mechanical trauma. Orbital emphysema tends to develop in fractures affecting the paranasal sinuses and walls of the orbit. CLINICAL CASE: We report the case of a 35-year-old male who suffered an orbital floor fracture with associated orbital emphysema as a result of nose blowing. DISCUSSION: Only one other similar case has been found in the literature.
