Assuntos
Neoplasias Abdominais , Neoplasia Endócrina Múltipla Tipo 2a , Neoplasias Primárias Múltiplas , Paraganglioma , Neoplasias Abdominais/diagnóstico , Feminino , Humanos , Pessoa de Meia-Idade , Neoplasia Endócrina Múltipla Tipo 2a/diagnóstico , Neoplasias Primárias Múltiplas/diagnóstico , Paraganglioma/diagnósticoRESUMO
La pancreatitis del surco representa una forma segmentaria de pancreatitis crónica que afecta la región periduodenal, entre la pared duodenal y el páncreas. Esta entidad es poco frecuente y posee ciertas características clínico patológicas que permiten identificarla preoperatoriamente. Esta condición ha recibido varios nombres entre estos: distrofia quística del páncreas heterotópico, hamartoma pancreático del duodeno, quiste paraduodenal y mioadenomatosis del páncreas. Presentamos dos casos de pancreatitis del surco en piezas de duodenopancreatectomía en hombres de 39 y 50 años, ambos bebedores de alcohol. Los estudios de imagen mostraron en ambos lesiones quísticas intrapancreáticas. Histológicamente se observó engrosamiento de la mucosa duodenal, hiperplasia severa de las glándulas de Brunner, proliferación miofibroblástica con formaciones quísticas, entremezclada con tejido pancreático e inflamación crónica. Esta entidad entra en el diagnóstico diferencial de las lesiones pseudotumorales pancreáticas que pueden simular carcinoma(AU)
Groove pancreatitis is a form of chronic segmental pancreatitis affecting the periduodenal region between the duodenum and the head of the páncreas. This uncommon entity has distinct clinicopathological features which facilitate its preoperative diagnosis. It is also been known as cystic dystrophy in heterotopic páncreas, pancreatic hamartoma of the duodenum, paraduodenal cyst and adenomyomatosis of the páncreas. We present two cases of groove pancreatitis in adult males aged 39 and 50, both alcohol drinkers, who had undergone pancreatoduodenectomy. Imaging studies showed cystic intrapancreatic lesions. Histologically, a large duodenal wall with prominent myofibroblastic proliferation and cysts admixed with pancreatic tissue and cronic inflammation was seen. Groove pancreatitis may be confused with carcinoma(AU)
Assuntos
Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Pancreatite/patologia , Glândulas Duodenais/patologia , Neoplasias Pancreáticas/patologia , Pancreatectomia/métodos , Pancreatectomia/tendências , Pancreaticoduodenectomia/métodos , Pancreaticoduodenectomia/tendências , Ductos Pancreáticos/patologia , Diagnóstico Diferencial , Granuloma de Células Plasmáticas/patologia , Duodenopatias/patologia , Neoplasias Duodenais/patologiaRESUMO
El carcinoma intraductal de glándula salival mayor es un tumor agresivo tanto clínica como citológicamente. En glándula salival menor, son muy raros y a pesar de tener una citología agresiva son tumores con buen comportamiento clínico. Presentamos un caso en paladar blando, fácilmente diagnosticable por la presencia de abundantes células mioepiteliales que rodean conductos con células epiteliales grandes, atípicas, con mitosis y necrosis. Un año después de la extirpación permanece asintomático
Intraductal carcinoma of major salivary gland is a very agressive neoplasm in clinical and cytological grounds. In minor salivary gland it´s very rare and have a good clinical evolution irrespective of the cytological agressivity. We report a case in soft palate, without diagnostics problems by the easy demonstration of myoepithelial cells around all epithelial units.The epithelial cells are large, atypical with mitosis and necrosis.A year later the patient is well
Assuntos
Humanos , Masculino , Idoso , Glândulas Salivares Menores/patologia , Neoplasias das Glândulas Salivares/patologia , Carcinoma Intraductal não Infiltrante/patologia , Mioepitelioma/patologia , Proteínas S100/análiseRESUMO
El pólipo fibroepitelial estromal es una entidad benigna, cuya peculiaridad más importante es la variedad de hallazgos histopatológicos que puede presentar, y que todavía frecuentemente se diagnostica erróneamente como maligno, a pesar de que es una entidad bastante bien estudiada en la literatura. Hemos recogido nuestra casuística en los últimos 5 años y revisado la literatura (AU)
Assuntos
Adulto , Feminino , Pessoa de Meia-Idade , Humanos , Pólipos/patologia , Neoplasias dos Genitais Femininos/patologia , Neoplasias Fibroepiteliais/patologiaRESUMO
Epithelioid-cell blue nevus is an unusual cytologic variant of blue nevus that has been recently described mostly in patients with Carney complex, although the lesion may also appear in patients with no evidence of Carney complex. This variant of blue nevus is composed of melanin laden large polygonal epithelioid melanocytes situated within the dermis. The neoplastic cells show no maturation with progressive descent and, in contrast with the usual stromal changes in blue nevi, epithelioid-cell blue nevus exhibits no dermal fibrosis. This report describes a congenital giant melanocytic nevus with pigmented epithelioid cells located on the back of a 2-year-old male. The lesion was present at birth and the patient had no evidence of Carney complex. Histopathologically, the lesion consisted of a large and entirely intradermal melanocytic nevus composed of heavily pigmented epithelioid melanocytes involving the full-thickness of dermis, but extending also to the subcutaneous fat and underlying soft tissues. Immunohistochemically, epithelioid neoplastic melanocytes expressed immunoreactivity for S-100 protein, HMB-45, Melan-A, NK1C3, and microphthalmia transcription factor (MiTF) antibodies. MIB-1 cellular proliferation marker was expressed in the nuclei of only a few scattered epithelioid melanocytes. This report demonstrates that epithelioid-cell blue nevus is a distinctive histopathologic variant of blue nevus that may also appear as a giant congenital melanocytic nevus.
