RESUMO
Sympathetic innervation of the stomach is carried out by the prevertebral ganglia of the solar plexus. The localization and neurochemical composition of neurons innervating the stomach in postnatal ontogenesis in rats was studied using the method of retrograde axon transport of Fast Blue. In all animals, the celiac ganglia had more labeled neurons compared to the superior mesenteric ganglion. The number of labeled neurons increased in the first 10 days of life and then did not change until the senescence. All labeled neurons innervating the stomach contain the catecholamine synthesis enzyme, tyrosine hydroxylase. The proportion of labeled neuropeptide Y-immunopositive neurons did not change in the development, the percentage of labeled calbindin-immunoreactive neurons decreased in the first month of life.
Assuntos
Envelhecimento/fisiologia , Gânglios Simpáticos/citologia , Estômago/inervação , Animais , Neurônios/metabolismo , Neuropeptídeo Y , Ratos , Tirosina 3-Mono-OxigenaseAssuntos
Regeneração Nervosa/fisiologia , Oligopeptídeos/uso terapêutico , Neuropatia Ciática/tratamento farmacológico , Animais , Masculino , Mecanorreceptores/metabolismo , Regeneração Nervosa/efeitos dos fármacos , Oligopeptídeos/farmacologia , Ratos , Ratos Wistar , Neuropatia Ciática/patologia , Fatores de Tempo , Tato/fisiologiaRESUMO
We measured changes in the frequency of hypothalamic self-stimulation in cats during their stays in a normal-oxygen nitrogen-oxygen environment under a pressure of 6 kg/cm2. A 200-300% increase in the frequency of self-stimulation was observed during the initial exposure. A depression of the reaction with a subsequent normalization by the third day took place after decompression. The second exposure led to an adaptation of the organisms to the effect of the elevated partial pressure of nitrogen. It is suggested that the changes in the self-stimulation reaction are connected with the "narcotic" effect of nitrogen under elevated pressures.
Assuntos
Hipotálamo/efeitos dos fármacos , Nitrogênio/farmacologia , Oxigênio/farmacologia , Autoestimulação/fisiologia , Pressão do Ar , Animais , Gatos , Hipotálamo/fisiologiaRESUMO
Correlation between the frequency of bar pressing and the frequency of hypothalamic self-stimulation of fixed duration was studied in cats during changes in strength of the stimulating current. Strong direct correlation was found between the frequency of bar pressing and the frequency of self-stimulation, whereas strong negative correlation was found between the frequency of pressing and the animal's "work effectiveness." It is suggested that the strongest motivation arises in the presence of an optimal strength of self-stimulation, giving rise to maximal frequency of bar pressing.