RESUMO
BACKGROUND: Information is lacking concerning in-hospital echocardiography analysis of COVID-19 infection in Brazil. We evaluated echocardiographic parameters to predict a composite endpoint of mortality, pulmonary thromboembolism or acute renal failure. METHODS: A prospective full echocardiographic study of consecutive patients hospitalized with COVID-19, single tertiary centre in Brazil. We correlated echocardiographic findings to biomarkers, clinical information, thoracic tomography, and in-hospital composite endpoint of mortality, pulmonary thromboembolism or renal failure. RESULTS: One hundred eleven patients from March to October 2020, 67 ± 17 years, 65 (58.5%) men, death was observed in 21/111 (18.9%) patients, 48 (43%) required mechanical ventilation, myocardial infarction occurred in 10 (9%), pulmonary thromboembolism in 7 (6.3%) patients, haemodialysis was required for 9 (9.8%). Echocardiography was normal in 51 (46%) patients, 20 (18%) presented with decreased left ventricle ejection, 18 (16.2%) had abnormal left ventricle global longitudinal strain, 35 (31%) had diastolic dysfunction, 6 (5.4%) had an E/e'ratio > 14, 19 (17.1%) presented with right ventricle dilated/dysfunction, 31 (28%) had pericardial effusion. The echocardiographic parameters did not correlate with mortality, biomarkers, clinical events. Tricuspid velocity was related to the composite endpoint of mortality, pulmonary thromboembolism or acute renal failure (p: 00.3; value: 2.65 m/s; AUC ROC curve: 0.739; sensitivity: 73.3; specificity: 66.7; CI: 0.95, inferior: 0.613; superior: 0,866). CONCLUSIONS: Among hospitalized patients with COVID-19, echocardiography was normal in 51(46%) patients, and 20 (18%) patients presented with a decreased left ventricle ejection fraction. Tricuspid velocity was related to the composite endpoint of mortality, pulmonary thromboembolism or acute renal failure.
Assuntos
COVID-19 , Brasil/epidemiologia , Ecocardiografia , Hospitais , Humanos , Masculino , Prognóstico , Estudos Prospectivos , SARS-CoV-2RESUMO
Classicamente, a cardiomiopatia de Takotsubo caracteriza-se por alteração transitória da contratilidade regional envolvendo o ápex e os segmentos médios do ventrículo esquerdo, com segmentos basais hipercontráteis, na ausência de doença coronária obstrutiva. Recentemente, casos de disfunção regional do ventrículo esquerdo induzidos pelo estresse, com padrões alternativos de disfunção regional em que o ápex é geralmente poupado (Takotsubo Invertido), têm sido relatados. Neste relato é descrito um caso de miocardiopatia induzida pelo estresse, no qual alterações da contratilidade segmentar foram observadas somente nos segmentos médios dos ventrículos, formando uma região acinética em faixa em torno do coração.