Assuntos
Síndrome de Ehlers-Danlos , Mutação da Fase de Leitura , Canais Iônicos/genética , Cifose , Doenças Neuromusculares , Escoliose , Criança , Síndrome de Ehlers-Danlos/genética , Síndrome de Ehlers-Danlos/patologia , Síndrome de Ehlers-Danlos/fisiopatologia , Feminino , Humanos , Cifose/genética , Cifose/patologia , Cifose/fisiopatologia , Doenças Neuromusculares/genética , Doenças Neuromusculares/patologia , Doenças Neuromusculares/fisiopatologia , Escoliose/genética , Escoliose/patologia , Escoliose/fisiopatologiaRESUMO
A syndrome now known as Ehlers-Danlos, comprising laxity and fragility of the skin associated with hypermobility of the large joints, was published in 1892 by Tschernogobow. Ehlers-Danlos type VIIA is an extremely rare form of the syndrome. While the UK-based Ehlers-Danlos Support Group recommends that the surgical management of patients with Ehlers-Danlos VIIA should be carried out in conjunction with a plastic surgeon, there is nothing in the plastic surgery literature regarding this syndrome. The management of patients suffering from Ehlers-Danlos VIIA is highly complex, as a result of the breadth of genetic and phenotypic presentations, and resulting complications. We present a review of the literature regarding this syndrome and, in particular, the surgical problems that may be encountered. A case report outlining our experience of successfully managing this condition is also presented.
