[Clinical symptoms and personality traits in patients using psychostimulant drugs and other psychoactive substances]. / Klinicheskie i lichnostnye osobennosti bol'nykh, upotrebliaiushchikh psikhostimuliatory i drugie psikhoaktivnye veshchestva.

AIM: To obtain preliminary data on personality and clinical/psychopathological predictors of combined use of psychoactive drugs in patients with psychostimulant dependence. MATERIAL AND METHODS: Eighty-nine inpatients were examined. Family history of drug dependence, personality disorders, clinical/psychopathological characteristics and disease course (breakdowns, relapses, remissions) were compared in patients with psychostimulant dependence (n=35) and patients who used other psychoactive substances (n=54). RESULTS AND CONCLUSION: Combined use of psychoactive substances is predicted by a complex of factors, including genetic, biological (neurochemical), psychological (personality characteristics of comorbidity and social influences). Based on their proportion, three types of psychostimulant dependence were determined.

[The efficiency of the medical rehabilitation program with the use of injectable naltrexone for alcohol addicted patients who are at risk of parental rights deprivation]. / Éffektivnost' programmy meditsinskoi reabilitatsii s ispol'zovaniem in''ektsionnogo naltreksona u bol'nykh s alkogol'noi zavisimost'iu, nakhodiashchikhsia v gruppe riska po lisheniiu roditel'skikh prav.

AIM: To evaluate the efficacy of treatment of patients at risk of deprivation of parental rights due to alcohol dependence under the 'Point of Soberness' program including psychotherapy and intramuscular injections of extended-release naltrexone (vivitrol). MATERIAL AND METHODS: Results of therapy of 45 patients, 39 women and 6 men, are presented. Out of 45 patients, 42 (93.3%) received a full course of injections of prolonged naltrexone (6 or more) as part of a comprehensive outpatient rehabilitation program. RESULTS AND CONCLUSION: Thirty-six (80.0%) patients maintained a remission. In 9 patients (20.0%), single breakdowns and breakdowns, resulting in a relapse of the disease were recorded. Forty-two patients (93.3%) retained their parental rights. The return of children was made in one case. The 'Point of Soberness' program makes it possible to achieve long remission of alcohol dependence, and to keep parental rights for these patients.

[An interim analysis of the results of treatment program implementation with the use of injectable extended-release naltrexone for opioid addicted patients]. / Promezhutochnyi analiz rezul'tatov realizatsii programmy lecheniia stradaiushchikh narkoticheskoi zavisimost'iu patsientov prolongirovannym in''ektsionnym naltreksonom.

AIM: To analyze outcomes of treatment in the 'Point of soberness' program for opioid addicted patients (2015-2016 гг.). MATERIAL AND METHODS: The results of treatment of 83 opioid addicted patients were analyzed. Seventy-four (89.16%) patients received treatment course of injections of extended-release naltrexone (from 4 to 6 injections), maintaining their participation in the outpatient medical rehabilitation program. Thirty-six (43.37%) patients completed a full course of injections of extended-release naltrexone. RESULTS AND CONCLUSION: The high efficacy of complex treatment with naltrexone injections was demonstrated. 89% of patients achieved remission during the course of treatment.

[Cognitive impairment in patients with opioid addiction].

The authors present the results of a study on cognitive dysfunction in 77 patients with opioid addiction. Cognitive functions were assessed with a battery of neuropsychological tests after stopping the syndrome of opiate withdrawal. Significant impairment of memory, memorization, attention, generalization and abstract thinking were identified in the majority of patients.