1.
Mol Biol (Mosk)
; 35(2): 309-20, 2001.
Artigo
em Russo
| MEDLINE
| ID: mdl-11357413
RESUMO
The structure and in vivo functions of the glial cell-derived neurotrophic factor (GDNF) family ligands (GFLs) and their high-affinity receptors are considered. These proteins play an important role in the development of the nervous system, morphogenesis of the kidneys, and in regulation of spermatogenesis. Tyrosine kinase Ret is a receptor component common for all GFLs. Its role in multiple endocrine neoplasia type 2 (MEN2) is discussed.