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1.
Environ Sci Technol ; 52(15): 8488-8500, 2018 08 07.
Artigo em Inglês | MEDLINE | ID: mdl-29979581

RESUMO

Traces of particulate radioactive iodine (131I) were detected in the European atmosphere in January/February 2017. Concentrations of this nuclear fission product were very low, ranging 0.1 to 10 µBq m-3 except at one location in western Russia where they reached up to several mBq m-3. Detections have been reported continuously over an 8-week period by about 30 monitoring stations. We examine possible emission source apportionments and rank them considering their expected contribution in terms of orders of magnitude from typical routine releases: radiopharmaceutical production units > sewage sludge incinerators > nuclear power plants > spontaneous fission of uranium in soil. Inverse modeling simulations indicate that the widespread detections of 131I resulted from the combination of multiple source releases. Among them, those from radiopharmaceutical production units remain the most likely. One of them is located in Western Russia and its estimated source term complies with authorized limits. Other existing sources related to 131I use (medical purposes or sewage sludge incineration) can explain detections on a rather local scale. As an enhancing factor, the prevailing wintertime meteorological situations marked by strong temperature inversions led to poor dispersion conditions that resulted in higher concentrations exceeding usual detection limits in use within the informal Ring of Five (Ro5) monitoring network.


Assuntos
Poluentes Radioativos do Ar , Neoplasias da Glândula Tireoide , Europa (Continente) , Humanos , Radioisótopos do Iodo , Federação Russa
2.
Sci Total Environ ; 566-567: 238-249, 2016 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-27220101

RESUMO

The purpose of this study is to evaluate the contamination in As, Ba, Co, Cu, Mn, Ni, Sr, V, Zn and REE, in a high uranium activity (up to 21,000Bq∙kg(-1)) area, downstream of a former uranium mine. Different geochemical proxies like enrichment factor and fractions from a sequential extraction procedure are used to evaluate the level of contamination, the mobility and the availability of the potential contaminants. Pb isotope ratios are determined in the total samples and in the sequential leachates to identify the sources of the contaminants and to determine the mobility of radiogenic Pb in the context of uranium mining. In spite of the large uranium contamination measured in the soils and the sediments (EF≫40), trace element contamination is low to moderate (2

Assuntos
Sedimentos Geológicos/análise , Radioisótopos de Chumbo/análise , Mineração , Poluentes do Solo/análise , Oligoelementos/análise , Monitoramento Ambiental , França , Urânio
3.
J Environ Radioact ; 149: 110-20, 2015 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-26232768

RESUMO

This study combines in situ gamma spectrometry performed at different scales, in order to accurately locate the contamination pools, to identify the concerned radionuclides and to determine the distribution of the contaminants from soil to bearing phase scale. The potential mobility of several radionuclides is also evaluated using sequential extraction. Using this procedure, an accumulation area located downstream of a former French uranium mine and concentrating a significant fraction of radioactivity is highlighted. We report disequilibria in the U-decay chains, which are likely related to the processes implemented on the mining area. Coupling of mineralogical analyzes with sequential extraction allow us to highlight the presence of barium sulfate, which may be the carrier of the Ra-226 activities found in the residual phase (Ba(Ra)SO4). In contrast, uranium is essentially in the reducible fraction and potentially trapped in clay-iron coatings located on the surface of minerals.


Assuntos
Sedimentos Geológicos/análise , Monitoramento de Radiação/métodos , Poluentes Radioativos do Solo/análise , Urânio/análise , França , Mineração , Espectrometria gama
4.
J Environ Radioact ; 141: 1-7, 2015 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-25500060

RESUMO

Uranium and thorium isotopes were measured in cypress leaves, wheat grains and lettuce taken in the surroundings of the uranium conversion facility of Malvési (South of France). The comparison of activity levels and activity ratios (namely (238)U/(232)Th and (230)Th/(232)Th) in plants with those in aerosols taken at this site and plants taken far from it shows that aerosols emitted by the nuclear site (uranium releases in the atmosphere by stacks and (230)Th-rich particles emitted from artificial ponds collecting radioactive waste mud) accounts for the high activities recorded in the plant samples close to the site. The atmospheric deposition process onto the plants appears to be the dominant process in plant contamination. Dry deposition velocities of airborne uranium and thorium were measured as 4.6 × 10(-3) and 5.0 × 10(-3) m s(-1), respectively.


Assuntos
Poluentes Radioativos do Ar/metabolismo , Chamaecyparis/metabolismo , Exposição Ambiental , Lactuca/metabolismo , Tório/metabolismo , Triticum/metabolismo , Urânio/metabolismo , Poluentes Radioativos do Ar/análise , França , Folhas de Planta/metabolismo , Monitoramento de Radiação , Tório/análise , Urânio/análise
5.
Transfus Clin Biol ; 19(4-5): 182-6, 2012 Nov.
Artigo em Francês | MEDLINE | ID: mdl-23006955

RESUMO

One of the main goals of haemovigilance is to gather and analyze adverse events in recipients of blood products in order to improve blood safety. The French National Blood Service has a specific role in the management of immediate adverse events: to alert to quarantine the potentially dangerous blood products from the same donation(s), to provide blood testing for the etiologic assessment and to give transfusion advice to patients. The updating of the recipient's computer file allows a better monitoring for both immediate and delayed adverse events. Finally, the French National Blood Service's correspondent of haemovigilance is responsible for donor's inquiries, especially in cases of transfusion related to bacterial contamination, severe allergy, suspicion of transfusion acute related lung injury and viral seroconversion. The management effectiveness for adverse events requires a strong collaboration between all members of the haemovigilance network.


Assuntos
Segurança do Sangue , Reação Transfusional , França , Instalações de Saúde , Humanos , Qualidade da Assistência à Saúde
6.
J Environ Monit ; 14(11): 2902-12, 2012 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-23001397

RESUMO

The activity concentrations of radionuclides within the uranium and thorium series were determined in wheat and lettuce at five sites in France, and in their respective potential sources: crop soils of wheat and crop soils and irrigation waters of lettuce. These data were used to calculate concentration ratios and to enrich the database supported by the technical report series N°472 of the IAEA (2010). For wheat and lettuce, the activity concentrations were in the same range for all radionuclides studied, except for (210)Pb, which had higher activity concentrations in wheat, ranging between 1.3 and 11 Bq kg(−1) (fresh weight) as compared to 0.4 and 0.7 Bq kg(−1) (fresh weight) for lettuce. For wheat, the range of activity concentrations (mBq kg(−1); fresh weight) decreased as (210)Pb > (226)Ra (56­1511) ≈ (228)Ra (86­769) > (228)Th (19­176) ≈ (238)U (11­169) ≈ (234)U (12­150) ≈ (230)Th (9.08­197.18) ≈ (232)Th (8.61­121.45) > (235)U (0.53­7.9). For lettuce, it decreased as (228)Ra (<320­1221) > (210)Pb (409­746) > (226)Ra (30­599) ≈ (228)Th (<29­347) > (238)U (8­120) ≈ (234)U (8­121) ≈ (230)Th (5.21­134.63) ≈ (232)Th (5.25­156.99) > (235)U (0.35­5.63). The species differences may reflect different plant physiologies. Through the study of activity ratios of wheat and lettuce in relation with those of the various radionuclide sources it has been possible to highlight the contribution of the main sources of natural radionuclides. Indeed, irrigation water when the uranium concentration is enhanced (>30 mBq L(−1)) contributed significantly to the activity concentration of uranium in lettuces. Concerning the high activity concentrations of (210)Pb, it could be explained by atmospheric particle deposition. The effect of soil particles resuspension and their adhesion to the plant surface seemed to be important in some cases. The soil-to-plant transfer factors were calculated for lettuce and wheat. The values were lower in wheat than in lettuce except for (210)Pb which had similar values in the two species (0.11­0.13 respectively). For both species, (210)Pb followed by (228)Ra (0.015­0.10) and (226)Ra (0.010­0.051) displayed the highest transfer factor, whereas (238)U had intermediate values (0.0015­0.030) and (232)Th exhibited the lowest (0.0014­0.013).


Assuntos
Lactuca/química , Monitoramento de Radiação/métodos , Poluentes Radioativos do Solo/análise , Tório/análise , Triticum/química , Urânio/análise , França
7.
J Environ Monit ; 14(8): 2170-80, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22689007

RESUMO

Activity concentrations of the uranium and thorium series radionuclides were determined in chicken meat and eggs as well as in soil, water and other dietary intakes of poultry at five sites of the French territory. These data allow the calculation of transfer coefficients which enrich the database given by the technical report series no. 472 of the IAEA. In egg contents, the highest activity concentrations (in mBq kg(-1) fresh weight) are for (226)Ra, ranging between 136 and 190 and are much lower for uranium (between 0.51 and 1.30 for (238)U). In chicken meat, (238)U activity concentration is higher than in egg contents and ranges between 1.7 and 9.7. Concerning (232)Th, its activity concentration is lower than uranium and ranges between 0.5 and 4.9. Daily ingested activity concentration by the animals was assessed taking into account the activity concentrations measured in the grains, in the soil and in the drinking water. The activity concentration in grains and the daily intakes allow the calculation of concentration ratios and transfer coefficients for chicken meat and egg contents. In chicken meat the transfer coefficients (d kg(-1)) range between 0.0018 and 0.0073 for (238)U and between 0.0008 and 0.0028 for (232)Th. In egg contents they range from 0.00018 to 0.0018 for (238)U and are much higher for radium isotopes (0.10-0.23 for (226)Ra and 0.07-0.11 for (228)Ra).


Assuntos
Grão Comestível/química , Carne/análise , Óvulo/química , Poluentes Radioativos do Solo/análise , Tório/análise , Urânio/análise , Animais , Galinhas , Água Potável/química , Contaminação de Alimentos/análise , Água Doce/química , Modelos Químicos , Solo/química
8.
Environ Sci Technol ; 45(23): 9998-10003, 2011 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-22011198

RESUMO

Iodine-131 and various other radionuclides were released into the atmosphere from the damaged Japanese reactors of Fukushima Dai-ichi from 12 to 22 March 2011. The contaminated air mass was detected in France after 24 March; samples of grass, vegetables, and milk have been analyzed for (131)I by the IRSN, considering the fact that few values of iodine-131 transfer parameters have been directly measured in situ, due to the radioactive decay of this isotope. Data are compared with calculated values according to the air iodine concentration. The apparent dry deposition velocity of iodine on grass is therefore estimated to range between 1 × 10(-3) and 5 × 10(-3) m s(-1) from site to site. In addition, the grass to milk transfer factors are 2.8 × 10(-2) and 3.6 × 10(-3) d L(-1) for goat's and cow's milk respectively. These parameters fit well with the current values usually considered for radioecological assessment.


Assuntos
Contaminação Radioativa de Alimentos/análise , Radioisótopos do Iodo/análise , Leite/química , Reatores Nucleares , Liberação Nociva de Radioativos , Verduras/química , Animais , Bovinos , Feminino , França , Japão , Poaceae/química
9.
J Environ Monit ; 13(5): 1327-36, 2011 May.
Artigo em Inglês | MEDLINE | ID: mdl-21487575

RESUMO

Cypress needles collected at the edge of the Malvési uranium facility (SW France) exhibit enhanced activities of actinides and some decay products (uranium, americium, plutonium, (230)Th, (226)Ra) compared to a remote site. These enhanced activities resulted from the release of U via smokestacks and passive release from former artificial ponds located inside the nuclear site. Enhanced activities are also observed in selected produce (wheat, lettuce, fruits) sampled from the edge of the site. However, excess actinides measured in wheat grains in 2007 are inconsistent with the activities and the uranium ratio measured in the soils. This result suggests that the studied annual crops were contaminated mainly through the short-term release of airborne actinides, and that other transfer pathways, such as, uptake through the roots or adhesion of soil particles, were negligible.


Assuntos
Elementos da Série Actinoide/análise , Produtos Agrícolas/química , Poluentes Radioativos/análise , Cupressus/química , Exposição Ambiental/análise , Exposição Ambiental/estatística & dados numéricos , Humanos , Folhas de Planta/química , Monitoramento de Radiação
10.
J Environ Monit ; 13(2): 355-61, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-21132170

RESUMO

Uranium and plutonium isotopes were measured in soils, sediments and waters in an area subject to the past and present discharges from the uranium conversion plant of Malvési (France). The isotopes (236)U and (239)Pu are well known activation products of uranium and they prove to be powerful tracers of spent fuel releases in soils and sediments. On the other hand (234)U and (238)U activities measured in waters can be used to distinguish between releases and background uranium sources. Such findings contribute to improve the monitoring of the actinides releases by nuclear fuel facilities (mining sites, conversion, enrichment and fuel plants, reprocessing plants).


Assuntos
Monitoramento Ambiental/métodos , Água Doce/análise , Sedimentos Geológicos/análise , Plutônio/análise , Poluentes Radioativos do Solo/análise , Solo/análise , Urânio/análise , Elementos da Série Actinoide/análise , França , Reatores Nucleares
11.
J Dairy Sci ; 92(11): 5363-70, 2009 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-19841196

RESUMO

This study aimed to compare the transfer of 2 manmade radionuclides, radiocesium (137Cs) and radiostrontium (90Sr), from cow milk to whey and cheese in 3 different types of French cheese production with rennet coagulation. Most of the 137Cs was present in the aqueous phase and became concentrated in the whey. For 137Cs transfer to whey, the processing factor (Pf; i.e., the ratio of the activity concentrations) ranged between 0.86 and 1.30 (n = 12). The food processing retention factor (Fr), calculated using the processing efficiency, ranged between 0.85 and 1.19 (n = 9). No statistical difference of Pf and Fr to whey is identified for 137Cs and the cheese products. The Pf calculated for 90Sr transfer to cheese ranged between 3.95 and 12.16, with significant differences depending on the type of cheese. In addition, a linear correlation is observed between 90Sr Pf to cheese and the Ca level in the cheese (r2 = 0.57). Thus, the Pf is enhanced in hard cheeses that are enriched in calcium. This is confirmed by nearly constant Fr values, ranging between 0.66 and 0.83.


Assuntos
Radioisótopos de Césio/análise , Queijo/análise , Contaminação Radioativa de Alimentos/análise , Leite/química , Radioisótopos de Estrôncio/análise , Animais , Cálcio/análise , Tecnologia de Alimentos , Minerais/análise , Radioisótopos de Potássio/análise
12.
J Environ Radioact ; 99(4): 680-93, 2008 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-17996340

RESUMO

Soils have been sampled in the vicinity of the Tomsk-Seversk facility (Siberia, Russia) that allows us to measure radioactive contaminations due to atmospheric and aquatic releases. Indeed soils exhibit large inventories of man-made fission products including 137Cs (ranging from 33,000 to 68,500 Bq m(-2)) and actinides such as plutonium (i.e. 239+240Pu from 420 to 5900 Bq m(-2)) or 241Am (160-1220 Bq m(-2)). Among all sampling sites, the bank of the Romashka channel exhibits the highest radioisotope concentrations. At this site, some short half-life gamma emitters were detected as well indicating recent aquatic discharge in the channel. In comparison, soils that underwent atmospheric depositions like peat and forest soils exhibit lower activities of actinides and 137Cs. Soil activities are too high to be related solely to global fallout and thus the source of plutonium must be discharges from the Siberian Chemical Combine (SCC) plant. This is confirmed by plutonium isotopic ratios measured by ICP-MS; the low 241Pu/239Pu and 240Pu/239Pu atomic ratios with respect to global fallout ratio or civil nuclear fuel are consistent with weapons grade signatures. Up to now, the influence of Tomsk-Seversk plutonium discharges was speculated in the Ob River and its estuary. Isotopic data from the present study show that plutonium measured in SCC probably constitutes a significant source of plutonium in the aquatic environment, together with plutonium from global fallout and other contaminated sites including Tomsk, Mayak (Russia) and Semipalatinsk (Republic of Kazakhstan). It is estimated that the proportion of plutonium from SCC source can reach 45% for 239Pu and 60% for 241Pu in the sediments.


Assuntos
Centrais Elétricas , Monitoramento de Radiação/métodos , Poluentes Radioativos do Solo/análise , Poluentes Radioativos da Água/análise , Amerício/análise , Radioisótopos de Césio/análise , Geografia , Cazaquistão , Plutônio/análise , Cinza Radioativa , Liberação Nociva de Radioativos , Poluentes Radioativos/análise , Radioisótopos , Federação Russa , Solo/análise
13.
Ultrasound Med Biol ; 33(3): 430-8, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-17276580

RESUMO

Fetal heart rate (FHR) monitoring is a crucial part of monitoring at-risk pregnancies and labor. Its aim is to detect any abnormalities that might indicate acute fetal distress and a need for rapid treatment to avoid death or serious sequelae, including cerebral handicap. The use of fetal biophysical profiles in high-risk pregnancies (gravidic hypertension, in utero infection, etc.) helps to distinguish healthy fetuses from those with chronic conditions. Fetal biophysical profile scores have been developed that integrate five biophysical parameters, one of which is derived from the FHR. The major parameters detected are the rate of fetal movements, fetal tone, fetal breathing movement and amniotic fluid volume. All of those parameters except FHR are obtained by prolonged echographic observation and cannot be used routinely. We developed in this study a new multigate multitransducer pulsed Doppler system for survey of fetal behavior. Fast Fourier transform and autocorrelation function have been used for processing and analyzing ultrasonic Doppler signals generated by fetal movements. Several parameters are analyzed in each of the 12 x 5 = 60 Doppler gates: amplitude of signals reflected by moving fetal structures, velocity, direction and amplitude of displacement of fetal structure (heart, chest, limbs). From these parameters it is possible to calculate FHR and characterize fetal activity. Preliminary in vivo results obtained in 15 pregnant women (30 to 36 wk) are very encouraging but they have yet to be confirmed in future studies. These results also demonstrate the advantages of transducers designed for improved fetal movement detection. The algorithms needs to be precise enough to allow the Actifetus system to function in real time. We now have at our disposal some algorithms that succeed in quantifying FHR and fetal movements with a signal from a given sensor at a given depth. This study confirms the feasibility of monitoring fetal movements by the Actifetus system and demonstrates the importance of the characterization of fetal rhythms (and fetal behavior). The Actifetus system will serve as a new mean for studying fetal response to environment and detecting anomalies related to fetal suffering.


Assuntos
Monitorização Fetal/instrumentação , Movimento Fetal/fisiologia , Ultrassonografia Doppler/instrumentação , Ultrassonografia Pré-Natal/instrumentação , Algoritmos , Ecocardiografia Doppler/instrumentação , Ecocardiografia Doppler/métodos , Desenho de Equipamento , Monitorização Fetal/métodos , Análise de Fourier , Frequência Cardíaca Fetal/fisiologia , Humanos , Processamento de Imagem Assistida por Computador/instrumentação , Processamento de Imagem Assistida por Computador/métodos , Perna (Membro) , Processamento de Sinais Assistido por Computador/instrumentação , Transdutores , Ultrassom , Ultrassonografia Doppler/métodos , Ultrassonografia Pré-Natal/métodos
14.
Chemosphere ; 66(8): 1571-9, 2007 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-17005236

RESUMO

Contamination of the environment by radionuclides is usually estimated using soil and grass sampling. However, radionuclides are often not homogeneously distributed in soils. In the alpine Mercantour region (Western Alps, France) a large heterogeneity in Chernobyl 137Cs deposition has been previously observed. Here we report additional 137Cs results together with new 90Sr and Pu data for soil, grass, milk, and cheese samples. The results show that radioisotopes from nuclear weapons tests fallout are more homogeneously distributed than Chernobyl 137Cs. Further, we observe that the 137Cs and 90Sr contents are less variable in milk samples than in grass or soil samples. This can be attributed to the homogenization effect of cow vagrancy during grazing. Hence milk seems to be a more robust sample than soil or grass to evaluate the extent of contamination on a regional scale. We explore this idea by comparing own unpublished 90Sr results and 90Sr results from the literature to establish the relationship between altitude of grazing and contamination of soil and milk for Western Europe. There is a significant positive correlation between soil contamination and altitude and an even closer correlation between milk 90Sr activity (A) and altitude (h): A = A0 + e(k x h) where A0 is the expected activity of milk sampled at sea level (A0 = 0.064 +/- 0.014 Bq g(-1) Ca) and h is the altitude of grazing, k being a constant (k = 0.95 x 10(-3) +/- 0.11 x 10(-3) m(-1) Bq g(-1) Ca). The fact that there is less scattering in the relationship for the 90Sr(milk)-altitude than for 90Sr(soil)-altitude suggests, again, that milk is a well-suited sample for environmental survey. The relationship between the altitude of grazing and the 90Sr content of milk and cheese can also be used to assess the authenticity of dairy products.


Assuntos
Laticínios/análise , Radioisótopos/análise , Poluentes Radioativos do Solo/análise , Animais , Radioisótopos de Césio/análise , Europa (Continente) , Leite/química , Modelos Biológicos , Plantas/química , Poaceae/química , Radioisótopos de Estrôncio/análise
15.
J Environ Radioact ; 91(3): 146-59, 2006.
Artigo em Inglês | MEDLINE | ID: mdl-17049415

RESUMO

A field study was carried out along the Golfe du Lion, that focussed on the beaches of the Camargue, to locate the main areas where enriched U and Th are found, and to better understand the processes that concentrate radioactivity on beaches. Indeed enriched areas are observed on some Camargue beaches, where high-dose rates are recorded due to excess U and Th activity (>1000 Bq kg(-1)). The coastline was mapped by means of an aerial gamma survey and the results indicated that the main actinides deposits occurred in the Camargue area. This concentrating effect is possibly due to a greater sedimentary contribution from the River Rhone relative to other minor Mediterranean rivers. Across the along-shore profile, the variability in actinides observed at the eastern part of Beauduc spit is mainly explained by variations in heavy and light mineral contents. Such variability can be accounted for by redistribution of the sand caused by erosion/deposition processes occurring in the eastern part of the spit. Further parameters such as grain size and heavy minerals content were studied in connection with the distribution of U, Th and (40)K in the field at a more localised level (i.e. across-shore beach profile). The <200-micro m fraction contains more than 50% of the radioactivity and heavy minerals (especially zircon) are the main contributors to the high levels of external radiation. Therefore the enriched areas, where U and Th exceed 1000 Bq kg(-1), presumably result from the sorting of sand grains according to their size and density.


Assuntos
Radiação de Fundo , Praias , França , Metais Pesados/análise , Óxidos/análise , Dióxido de Silício/química , Poluentes Radioativos do Solo/análise , Tório/análise , Urânio/análise
16.
Magn Reson Imaging ; 22(4): 457-65, 2004 May.
Artigo em Inglês | MEDLINE | ID: mdl-15120164

RESUMO

Cerebral hypoxia-ischemia (HI) is an important cause of perinatal brain damage in the term newborn. The areas most affected are the parasagittal regions of the cerebral cortex and, in severe situations, the basal ganglia. The aim of this study was to show that the newborn piglet model can be used to produce neuropathology resulting from moderate HI insult and to monitor damage for 7 days. Two acute cerebral HI were induced in newborn Large White piglets by reducing the inspired oxygen fraction to 4% and occluding the carotid arteries. Newborn piglets were resuscitated, extubated and monitored for 7 days. (31)P magnetic resonance spectroscopy (MRS) offers the ability to monitor the severity of the HI insults. Lactate (Lac) was detected in the HI group at 2 h, 3 days and 5 days after insult by (1)H MRS. Lac/n-acetylaspartate and Lac/choline and Lac/creatine ratios increased significantly (p < 0.01) in the HI group 2 h after HI insults and remained high over 7 days. For the HI group, mean T(2) values increased significantly in the parietal white matter (subcortical) for 5 days after HI insult [117.5 (+/-7.4) to 158.5 (+/-19.2) at T+3 days, 167.7 (+/-15.4) at T+5 days and 160.9 (+/-10.1) at T+7 days (p < 0.01)]. This newborn piglet model of moderate HI brain injury with reproducible cerebral damage could be use as reference for the study of neuroprotective strategy for a period of 7 days.


Assuntos
Hidrogênio , Hipóxia-Isquemia Encefálica/diagnóstico , Imageamento por Ressonância Magnética , Compostos Radiofarmacêuticos , Animais , Animais Recém-Nascidos/metabolismo , Ácido Aspártico/análogos & derivados , Ácido Aspártico/metabolismo , Gânglios da Base/metabolismo , Gânglios da Base/fisiopatologia , Córtex Cerebral/metabolismo , Córtex Cerebral/fisiopatologia , Circulação Cerebrovascular , Modelos Animais de Doenças , Metabolismo Energético , Concentração de Íons de Hidrogênio , Hipóxia-Isquemia Encefálica/metabolismo , Hipóxia-Isquemia Encefálica/fisiopatologia , Ataque Isquêmico Transitório/diagnóstico , Ataque Isquêmico Transitório/metabolismo , Ataque Isquêmico Transitório/fisiopatologia , Ácido Láctico/metabolismo , Espectroscopia de Ressonância Magnética , Fosfocreatina/metabolismo , Isótopos de Fósforo , Índice de Gravidade de Doença , Acidente Vascular Cerebral/diagnóstico , Acidente Vascular Cerebral/metabolismo , Acidente Vascular Cerebral/fisiopatologia , Suínos
17.
Conf Proc IEEE Eng Med Biol Soc ; 2004: 1613-5, 2004.
Artigo em Inglês | MEDLINE | ID: mdl-17272009

RESUMO

Doppler has been used for many years for cardiovascular exploration in order to visualize the walls and anatomical or functional diseases. The use of ultrasound contrast agents makes it possible to improve ultrasonic information. Thus, harmonic imaging is a powerful tool for characterizing pathologies by their vascularity. However, images are buried in noise. We present an approach for noise reduction and structural features enhancement based on nonlinear anisotropic diffusion, coupled with fuzzy clustering segmentation to delineate liver pathologies.

18.
Br J Ophthalmol ; 86(11): 1243-7, 2002 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-12386080

RESUMO

BACKGROUND/AIM: Retinal vein occlusion (RVO) is one of the most frequent ocular vascular diseases and leads to severe vision impairment. Colour Doppler imaging (CDI) is the first method which allows distinct evaluation of arterial and venous velocities in RVO. CDI is valuable for diagnosis of RVO and shows the effects of isovolaemic haemodilution. Patients with RVO were monitored by CDI for 1 year in order to clarify venous and arterial involvement in the pathogenesis of this disease. METHODS: Patients with RVO were monitored prospectively for 1 year with clinical examinations, fluorescein angiography, and CDI every 3 months. 102 adults referred for RVO for less than 2 months were enrolled. Unaffected eyes were used as control. The maximum systolic and diastolic flow velocities and the resistance index (RI) were measured in the central retinal artery (CRA) and the maximum and minimum blood flow velocities in the central retinal vein (CRV). RESULTS: During the year of observation, branch retinal vein occlusion (BRVO), ischaemic central retinal vein occlusion (CRVO), and non-ischaemic CRVO had a distinct pattern of venous velocity changes. BRVO had a similar profile to that observed in controls. Venous velocities were continuously lower in central forms, with the lowest values in ischaemic occlusion. In contrast, a brief decrease in arterial diastolic velocity was observed in ischaemic CRVO at presentation, correlated with arteriovenous passage time on fluorescein angiography, but with rapid normalisation. CONCLUSIONS: CDI findings were correlated with the type of RVO at all times during follow up. CDI showed persistent impairment of central venous velocity in CRVO whereas there was a fast initial values recovery of the arterial velocity. These results using CDI show strong evidence of a primary venous mechanism in RVO.


Assuntos
Ecocardiografia Doppler em Cores , Oclusão da Veia Retiniana/diagnóstico por imagem , Adulto , Idoso , Velocidade do Fluxo Sanguíneo , Feminino , Angiofluoresceinografia , Seguimentos , Hemodinâmica , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Artéria Retiniana/fisiopatologia , Oclusão da Veia Retiniana/etiologia , Oclusão da Veia Retiniana/fisiopatologia , Fatores de Tempo
19.
Ultrasound Obstet Gynecol ; 19(1): 81-7, 2002 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-11851974

RESUMO

OBJECTIVES: To evaluate sonographic features following uterine artery embolization and to assess using ultrasound the efficacy of embolization as the primary treatment of fibroids. DESIGN: Fifty-eight women (mean age, 44.5 years; range, 33-65 years) suffering from symptoms due to fibroids (menometrorrhagia, bulk-related symptoms, pelvic pain) were followed-up after uterine artery embolization by ultrasound examination at 3 months, 6 months, 1 year and 2 years with assessment of volume and vascularization of fibroids as well as uterine vascularization. RESULTS: Fifty-eight patients were examined at 3 months, 46 at 6 months, 36 at 1 year and 19 at 2 years. Most patients were improved or free of symptoms at 3 months (90%), 6 months (92%) and 1 year (87%) and all monitored patients were free of symptoms at 2 years. Clinical failure of treatment occurred in only two cases (3%). Progressive significant reduction in fibroid size with reference to the baseline was demonstrated during follow-up from 3 months (-29%) to 24 months (-86%). Absence of intrafibroid vessels was observed in all except three cases as early as 3 months, whereas perifibroid vessels persisted in 21 cases. No changes in uterine vascularization or uterine artery resistance were noted. CONCLUSIONS: Uterine artery embolization is a valuable endovascular method for the treatment of fibroids, resulting in marked reduction in fibroid size and disappearance of intrafibroid vessels without reduction in uterine vascularization which is well depicted by sonography.


Assuntos
Embolização Terapêutica , Leiomioma/diagnóstico por imagem , Leiomioma/terapia , Neoplasias Uterinas/diagnóstico por imagem , Neoplasias Uterinas/terapia , Útero/irrigação sanguínea , Adulto , Idoso , Artérias , Feminino , Humanos , Pessoa de Meia-Idade , Estudos Prospectivos , Resultado do Tratamento , Ultrassonografia , Útero/diagnóstico por imagem
20.
Ultrasound Med Biol ; 27(11): 1515-23, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11750751

RESUMO

Autoregressive (AR) modelling has already been proposed as an alternative to fast Fourier transform to process ultrasound (US) Doppler signals. Previous works introduced long AR models, set up under a regularization framework. The latter may be in 1-D (frequency) or 2-D (frequency and space or time). This study generalizes the spectrum regularization in the three dimensions frequency, space and time. The problem of the penalization function is addressed, and a new convex solution is proposed, taking into account possible nonstationarity of the Doppler signal. The parameter tuning is based on simulations using a standard Doppler signal model. The first results show that this processing improves the spectral estimation, and is well suited to flow interpretation.


Assuntos
Artérias Carótidas/diagnóstico por imagem , Processamento de Sinais Assistido por Computador , Ultrassonografia Doppler/métodos , Algoritmos , Análise de Fourier , Coração/fisiologia , Humanos , Modelos Teóricos
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