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1.
Orphanet J Rare Dis ; 19(1): 325, 2024 Sep 06.
Artigo em Inglês | MEDLINE | ID: mdl-39243040

RESUMO

BACKGROUND: Classic galactosemia is a rare inherited metabolic disease with long-term complications, particularly in the psychosocial domain. Patients report a lower quality of social life, difficulties in interactions and social relationships, and a lower mental health. We hypothesised that social cognition deficits could partially explain this psychological symptomatology. Eleven adults with galactosemia and 31 control adults participated in the study. We measured social cognition skills in cognitive and affective theory of Mind, and in basic and complex emotion recognition. We explored psychosocial development and mental well-being. RESULTS: We found significant deficits on all 4 social cognition measures. Compared to controls, participants with galactosemia were impaired in the 2nd-order cognitive theory of mind, in affective theory of mind, and in basic and complex emotion recognition. Participants with galactosemia had a significant delay in their psychosexual development, but we found no delay in social development and no significant decrease in mental health. CONCLUSION: Social cognition processes seem impaired among our participants with galactosemia. We discuss the future path research may follow. More research is needed to replicate and strengthen these results and establish the links between psychosocial complications and deficits in social cognition.


Assuntos
Galactosemias , Cognição Social , Humanos , Galactosemias/psicologia , Feminino , Masculino , Adulto , Adulto Jovem , Pessoa de Meia-Idade
2.
Exp Brain Res ; 242(6): 1373-1385, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38565782

RESUMO

BACKGROUND AND OBJECTIVES: Alterations of the sensory-motor body schema question the origins of such distortions. For example, in anorexia nervosa where patients think they are broader than they really are (body image) but act as if it was really the case (body schema). To date, the results of studies about what hinders the updating of the body schema so much (weight, body image) have been contradictory. METHODS: We therefore conducted two studies that aimed to assess the impact of weight and body image problems on body schema in 92 young women without anorexia nervosa. For this purpose, we used a new body schema assessment tool (SKIN) that is sensitive enough to detect fine alterations of body schema in seven different body parts. RESULTS: In Study 1, the thinness or overweight of the young women had a major impact on their tactile perception, especially because the assessed body part was a sensitive area for body dissatisfaction in young women (e.g., belly, thigh). In Study 2, the level of body dissatisfaction of the participants in its attitudinal and perceptual dimension also had a negative impact on their body schema, again in interaction with weight and body part. CONCLUSIONS: These results imply that body dissatisfaction and thinness are predictors of massive body schema distortions. An oversized body schema could maintain various weight-control behaviors, thus risking the development, maintenance, or relapse of an eating disorder.


Assuntos
Imagem Corporal , Peso Corporal , Humanos , Feminino , Imagem Corporal/psicologia , Adulto Jovem , Peso Corporal/fisiologia , Adulto , Estudantes/psicologia , Adolescente , Universidades , Insatisfação Corporal , Inquéritos e Questionários , Percepção do Tato/fisiologia
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