Doxorubicin cardiotoxicity detected by indium 111 myosin-specific imaging.

A patient with primary hepatoma, treated with doxorubicin and presenting with atypical electrocardiographic findings, was investigated with myosin-specific monoclonal antibody radiolabelled with indium-111. Despite a normal ejection fraction, myosin-specific scintigraphy was positive, indicating doxorubicin cardiotoxicity.