RESUMO
Iphiona grantioides (Boiss) Anderb. is a medicinal plant featuring several traditional uses. Nevertheless, this plant has not been widely investigated by modern medicinal chemistry yet, as also the properties of its extracts.In this study, we report the extraction of the essential oil by hydrodistillation from the leaves of I. grantioides. This was characterised by GC-MS analysis and ten chemical constituents were identified.Our findings demonstrate that the essential oil is effective in inhibiting the growth of bacterial strains, and of Klebsiela pneumonia and Staphylococcus aureus in particular. Additionally, its antioxidant properties were evaluated, and it showed radical scavenging activity in vitro.
RESUMO
The recent epidemic of novel coronavirus (COVID-19) has turned out to be a huge public health concern owing to its fast transmission. Rapid and cost-effective detection of SARS-CoV-2 is crucial to classify diseased individuals. Serological examination based on antibody chromatography as a substitute to RT-PCR provides inadequate help owing to sophisticated personnel, false-positive results, special equipment and high cost. Biosensing techniques provide sensitive and specific detection, recognition and quantification of pathogens. Herein, after an introduction, we review potential electrochemical (EC) biosensors for COVID-19 diagnosis, emphasizing plasmonic, optical, colorimetric and aptamer-based sensors with a special focus on EC biosensors and point-of-care (POC) diagnostic methods. We have conferred the working principle of these biosensors, EC performance in terms of particular analytical figures of merit and their real-time applications in biological matrices. Lastly, we have described briefly the inactivation of SARS-CoV-2 by EC oxidation. In the end, we have concluded this review by clearing up the strengths and weaknesses of EC sensors and future directions. Advancement in research and technology would be our unsurpassed weapons in the fight against COVID-19 and preventing imminent pandemics.
