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J Orthop Surg Res ; 16(1): 695, 2021 Nov 27.
Artigo em Inglês | MEDLINE | ID: mdl-34838076

RESUMO

BACKGROUND: No prognostic model for the survival of fragile hip fracture has been developed for Asians. The goal of this study was to develop a simple and practical prognostic model to predict survival within 1 year after fragile hip fracture in Asians. METHODS: A single-center retrospective cohort study was designed. Under a multivariable Cox proportional hazards regression model, we used the preoperative characteristics of patients to predict survival within 1 year after hip fracture. We built a full model and then used the least absolute shrinkage and selection operator (LASSO) method to further shrink the model coefficients and achieved variable screening. Finally, we obtained a LASSO model. The model performance was evaluated with Nagelkerke's R2 and the concordance (c) statistic. We assessed the internal validity with a bootstrapping procedure of 1 000 repetitions. RESULTS: A total of 735 eligible patients were admitted to our department for hip fracture from January 2015 to December 2020, but 11 (1.5%) patients were lost to follow-up. Among the remaining patients, 68 (9.3%) died within 1 year after hip fracture. We identified 12 candidate predictors from the preoperative characteristics of the patients. The last model contained nine predictors: surgery, age, albumin, sex, serum creatinine, malignancy, hypertension, ability to live independently, and cardiovascular and cerebrovascular diseases. Among them, surgery, age, and albumin are effective predictors of survival. The discrimination c statistic of the model is 0.814 (95% confidence interval 0.762-0.865); the corrected value through internal validation is 0.795. CONCLUSIONS: This prognostic model can accurately predict a 1-year survival rate for patients with fragile hip fractures. This information can help clinicians develop a reasonable and personalized treatment plan.


Assuntos
Fraturas do Quadril/mortalidade , Albuminas , Povo Asiático , China/epidemiologia , Fraturas do Quadril/etnologia , Fraturas do Quadril/cirurgia , Humanos , Complicações Pós-Operatórias , Valor Preditivo dos Testes , Prognóstico , Estudos Retrospectivos , Fatores de Risco
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