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1.
Artigo em Inglês | MEDLINE | ID: mdl-34343062

RESUMO

A hyperthermophilic, strictly anaerobic archaeon, designated strain SY113T, was isolated from a deep-sea hydrothermal vent chimney on the Southwest Indian Ridge at a water depth of 2770 m. Enrichment and isolation of strain SY113T were performed at 85 °C at 0.1 MPa. Cells of strain SY113T were irregular motile cocci with peritrichous flagella and generally 0.8-2.4 µm in diameter. Growth was observed at temperatures between 50 and 90 °C (optimum at 85 °C) and under hydrostatic pressures of 0.1-60 MPa (optimum, 27 MPa). Cells of SY113T grew at pH 4.0-9.0 (optimum, pH 5.5) and a NaCl concentration of 0.5-5.5 % (w/v; optimum concentration, 3.0 % NaCl). Strain SY113T was an anaerobic chemoorganoheterotroph and grew on complex proteinaceous substrates such as yeast extract and tryptone, as well as on maltose and starch. Elemental sulphur stimulated growth, but not obligatory for its growth. The G+C content of the genomic DNA was 55.0 mol%. Phylogenetic analysis of the 16S rRNA sequence of strain SY113T showed that the novel isolate belonged to the genus Thermococcus. On the basis of physiological characteristics, average nucleotide identity values and in silico DNA-DNA hybridization results, we propose a novel species, named Thermococcus aciditolerans sp. nov. The type strain is SY113T (=MCCC 1K04190T=JCM 39083T).


Assuntos
Fontes Hidrotermais , Filogenia , Água do Mar/microbiologia , Thermococcus , Composição de Bases , DNA Arqueal/genética , Fontes Hidrotermais/microbiologia , Hibridização de Ácido Nucleico , RNA Ribossômico 16S/genética , Análise de Sequência de DNA , Thermococcus/classificação , Thermococcus/isolamento & purificação
2.
Math Biosci Eng ; 16(5): 4182-4195, 2019 05 13.
Artigo em Inglês | MEDLINE | ID: mdl-31499657

RESUMO

Based on quantum identity authentication, a novel continuous variable quantum steganography protocol is proposed in this paper. It can effectively transmit deterministic secret information in the public quantum channel by taking full advantage of entanglement properties of continuous variable GHZ state. Compared with the existing quantum steganography results, this protocol has the advantages of good imperceptibility and easy implementation. Finally, the detailed performance analysis proves that the proposed protocol has not only these advantages, but also good security and information transmission efficiency, even under eavesdropping attacks, especially to the spectroscopic noise attack.

3.
Math Biosci Eng ; 16(5): 4999-5021, 2019 05 31.
Artigo em Inglês | MEDLINE | ID: mdl-31499701

RESUMO

Since the good application of quantum mechanism in the field of communication, quantum secure communication has become a research hotspot. The existing quantum secure communication protocols usually assume that the quantum channel is noise-free. But the inevitable quantum noise in quantum channel will greatly interferes the transmission of quantum bits or quantum states, seriously damaging the security and reliability of the quantum system. This paper analyzes and discusses the performance of a χ state based steganography protocol under four main quantum noises, i.e., Amplitude Damping (AD), Phase damping (Phs), Bit Flip (BF) and Depolarizing (D). The results show that the protocol is least affected by amplitude damping noise when only the sender's first transmission in quantum channel is affected by quantum noise. Then, we analyze the performance of the protocol when both the sender's two transmissions are affected by quantum noise, and find that the specific combination of different noises will increase the performance of the protocol in quantum noisy channel. This means that an extra quantum noise can be intentionally added to quantum channel according to the noise intensity, so that the protocol can improve performance under the influence of quantum noises. Finally, the detailed mathematical analysis proves the conclusions.

4.
Nanomedicine (Lond) ; 10(1): 121-41, 2015 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-25597773

RESUMO

Nanoparticles (NPs) are widely applied in nanomedicine and diagnostics based on the interactions between NPs and the basic barrier (biomembrane). Understanding the underlying mechanism of these interactions is important for enhancing their beneficial effects and avoiding potential nanotoxicity. Experimental, mathematical and numerical modeling techniques are involved in this field. This article reviews the state-of-the-art techniques in studies of NP-biomembrane interactions with a focus on each technology's advantages and disadvantages. The aim is to better understand the mechanism of NP-biomembrane interactions and provide significant guidance for various fields, such as nanomedicine and diagnosis.


Assuntos
Membranas/efeitos dos fármacos , Nanomedicina , Nanopartículas/efeitos adversos , Humanos , Membranas/química , Nanopartículas/uso terapêutico
5.
Nanomedicine (Lond) ; 8(6): 995-1011, 2013 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-23730698

RESUMO

The widespread application of nanomaterials (NMs), which has accompanied advances in nanotechnology, has increased their chances of entering an organism, for example, via the respiratory system, skin absorption or intravenous injection. Although accumulating experimental evidence has indicated the important role of NM-biomembrane interaction in these processes, the underlying mechanisms remain unclear. Computational techniques, as an alternative to experimental efforts, are effective tools to simulate complicated biological behaviors. Computer simulations can investigate NM-biomembrane interactions at the nanoscale, providing fundamental insights into dynamic processes that are challenging to experimental observation. This paper reviews the current understanding of NM-biomembrane interactions, and existing mathematical and numerical modeling methods. We highlight the advantages and limitations of each method, and also discuss the future perspectives in this field. Better understanding of NM-biomembrane interactions can benefit various fields, including nanomedicine and diagnosis.


Assuntos
Membrana Celular/metabolismo , Nanoestruturas/análise , Animais , Endocitose , Humanos , Modelos Moleculares , Simulação de Dinâmica Molecular
6.
Chin J Traumatol ; 14(5): 301-3, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-22118486

RESUMO

Destructive injury is defined as a very serious damage both to the bone and the soft tissues. But in clinical practice we found that in some fracture cases, the damage to soft tissues is not as severe as "destructive injury" indicates, whereas comminuted fractures still cannot show the severity of bone damage. Therefore we proposed a new term "destructive fractures" after combining the definition of destructive injury with typical clinic cases. Destructive fractures refer to the fractures whose osseous tissues are damaged too seriously to be repaired, but soft tissues, nerves and veins are less severely injured and can be repaired. From the year 2001 to 2010, 75 cases of destructive fractures were admitted in our department. According to whether the fractures interlinked with the external environment, together with the fracture sites, they were divided into 6 types: a1 type, closed diaphysis destructive fracture; a2 type, open diaphysis destructive fracture; b1 type, closed joint-involved destructive fracture; b2 type, open joint-involved destructive fracture; c1 type, closed mixed destructive fracture; c2 type, open mixed destructive fracture. Corresponding clinical treatments were conducted for each type.The new classification criterion of destructive fracture is simple and practical and thus can be used as an important guide to make reasonable treatment plans for destructive fractures.


Assuntos
Fixação Interna de Fraturas , Fraturas Expostas , Fraturas Fechadas , Fraturas Cominutivas/cirurgia , Fraturas Expostas/cirurgia , Humanos
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