RESUMO
La terapia con luz es una alternativa en el tratamiento de la hidradenitis supurativa. El objetivo de este estudio fue evaluar la eficacia, la efectividad y la seguridad de las distintas modalidades de terapia con luz en la hidradenitis supurativa mediante una revisión sistemática que actualiza la realizada en 2015 procedente de la Cochrane Library. Se identificaron los estudios mediante una búsqueda electrónica en las bases de datos: MEDLINE, EMBASE, Centre for Reviews and Dissemination database de la Universidad de York, Cochrane Database of Systematic Reviews, Cochrane Skin Group Specialised Skin Register, Centre of Evidence Based Dermatology de la Universidad de Nottingham y TESEO; finalmente se incluyeron 6 series de casos, 3 revisiones sistemáticas y 2 ensayos clínicos de pacientes tratados con terapia fotodinámica convencional o intralesional, láser Nd:YAG, CO2 o diodo y luz intensa pulsada, con un total de 248 pacientes tratados
Treatment options for hidradenitis suppurativa include light-based therapy. This systematic review aimed to update our understanding of the efficacy, effectiveness and safety of these treatments for hidradenitis suppurativa by evaluating the literature published since the 2015 Cochrane review on this topic. We conducted an electronic search of the following databases: MEDLINE, EMBASE, University of York Centre for Reviews and Dissemination database, Cochrane Database of Systematic Reviews, Cochrane Skin Group Specialised Skin Register, University of Nottingham's Centre of Evidence Based Dermatology database, and TESEO. The systematic review included 6 case series, 3 systematic reviews, and 2 clinical trials on the use of conventional and intralesional photodynamic therapy, intense pulsed light therapy, and Nd:YAG, carbon dioxide, and diode laser therapy for hidradenitis suppurative in 248 patients
Assuntos
Humanos , Hidradenite Supurativa/terapia , Terapia de Luz Pulsada Intensa/métodos , Resultado do Tratamento , Terapia a Laser , Bibliometria , Análise de Dados , Perfil de Impacto da Doença , FotoquimioterapiaRESUMO
Treatment options for hidradenitis suppurativa include light-based therapy. This systematic review aimed to update our understanding of the efficacy, effectiveness and safety of these treatments for hidradenitis suppurativa by evaluating the literature published since the 2015 Cochrane review on this topic. We conducted an electronic search of the following databases: MEDLINE, EMBASE, University of York Centre for Reviews and Dissemination database, Cochrane Database of Systematic Reviews, Cochrane Skin Group Specialised Skin Register, University of Nottingham's Centre of Evidence Based Dermatology database, and TESEO. The systematic review included 6 case series, 3 systematic reviews, and 2 clinical trials on the use of conventional and intralesional photodynamic therapy, intense pulsed light therapy, and Nd:YAG, carbon dioxide, and diode laser therapy for hidradenitis suppurative in 248 patients.
Assuntos
Hidradenite Supurativa/terapia , Terapia de Luz Pulsada Intensa/métodos , Terapia a Laser/métodos , Fotoquimioterapia/métodos , Adulto , Feminino , Humanos , Lasers de Gás/uso terapêutico , Masculino , Avaliação de Resultados em Cuidados de Saúde , Estudos Prospectivos , Ensaios Clínicos Controlados Aleatórios como Assunto , Estudos RetrospectivosRESUMO
La dermatitis atópica (DA) es una dermatosis inflamatoria de curso crónico caracterizada por un intenso prurito. Se trata de una enfermedad multifactorial que resultaría de la interacción de factores genéticos, ambientales, defectos en la función barrera y una serie de factores inmunológicos. La DA afecta sobre todo a la infancia, pero también puede persistir o comenzar en el adulto. Caracterizada por un intenso prurito, morfología y distribución típica de sus lesiones, se ha convertido en la atracción de dermatólogos pediatras, pediatras, alergólogos e inmunólogos. Su prevalencia está aumentando y dos hechos son relevantes en la actualidad: el gran impacto en la calidad de vida de los pequeños pacientes y sus familias y la demostración, que es la primera manifestación del síndrome atópico. Las lesiones clínicas de la DA afectan típicamente a las flexuras, en forma de eczema exudativo o liquenificado; existe un número no despreciable de pacientes con lesiones de distribución o morfología atípica. Revisamos la etiopatogenia, criterios diagnósticos, clínica, diagnóstico diferencial y tratamiento, incidiendo en la terapéutica de la DA severa o refractaria a los tratamientos convencionales, haciendo especial hincapié en los recientes avances en el conocimiento de su fisiopatología, así como su manejo a través de algoritmos terapéuticos (AU)
Atopic dermatitis (AD) is the expression of a chronic inflammatory cutaneous disease that generally begins in the early childhood. Characterised by an intense pruritus and the morphology and distribution of its injuries, it is currently a field of interest for paediatric dermatologists, paediatricians, allergists and immunologists. Its prevalence is increasing and two facts are relevant at present: the adverse effect on the quality of life of the patients and the proof that is the first sign of the atopic syndrome. The controversies in the treatment guidelines are displacing the great advances in pathophysiology, as well as the managing of AD with algorithms is displacing the art of medical treatment (AU)
Assuntos
Humanos , Dermatite Atópica , Hipersensibilidade Imediata/fisiopatologia , Predisposição Genética para Doença/epidemiologia , Diagnóstico Diferencial , Corticosteroides/uso terapêutico , Fatores Imunológicos/uso terapêutico , Fenômenos do Sistema ImunitárioRESUMO
OBJECTIVE: To describe the clinical and histopathological manifestations of a case of pseudoepitheliomatous, keratotic and micaceous balanitis and review the literature on this rare condition. METHODS: A case of pseudoepitheliomatous, keratotic and micaceous balanitis in a 63-year-old man is presented. The lesion appeared a few months after undergoing circumcision due to phimosis and recurrent inflammatory balanitis. RESULTS: The lesion relapsed after topical treatment with 5-FU, cryotherapy and shaving-biopsy plus electrocoagulation. It was finally diagnosed as epidermoid carcinoma and surgically excised. CONCLUSIONS: The clinical and histopathological features, course and relationship between micaceous balanitis and carcinoma of the penis are reviewed.
Assuntos
Balanite (Inflamação)/patologia , Carcinoma de Células Escamosas/patologia , Neoplasias Penianas/patologia , Balanite (Inflamação)/terapia , Carcinoma de Células Escamosas/cirurgia , Terapia Combinada , Humanos , Hiperplasia , Masculino , Pessoa de Meia-Idade , Neoplasias Penianas/cirurgiaAssuntos
Leiomiomatose/patologia , Neoplasias Primárias Múltiplas/patologia , Neoplasias Cutâneas/patologia , Neoplasias Uterinas/patologia , Adulto , Feminino , Humanos , Leiomiomatose/fisiopatologia , Neoplasias Primárias Múltiplas/fisiopatologia , Dor/etiologia , Neoplasias Cutâneas/fisiopatologia , Síndrome , Neoplasias Uterinas/fisiopatologiaRESUMO
We report a case of cutaneous metastasis originating from prostate adenocarcinoma. We underscore this rare site of metastasis and the poor outcome.
Assuntos
Adenocarcinoma/secundário , Neoplasias Penianas/secundário , Neoplasias da Próstata , Neoplasias Cutâneas/secundário , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias da Próstata/mortalidade , Neoplasias da Próstata/patologia , Neoplasias Ureterais/secundário , Neoplasias da Bexiga Urinária/secundárioRESUMO
We report the case of a 35-year-old woman with paroxysmal unilateral hyperhidrosis which developed after thoractotomy for Barret's esophagus (benign esophageal stenosis). Hyperhidrosis was on the right side of the face and in the metameric areas corresponding to the right spinal roots C2, C3 and C4. Paroxysms of sweating lasting from 15 to 30 min occurred several times daily, either spontaneously or related with acid food ingestion. The symptoms have been present for the last 10 years. Paroxysmal unilateral hyperhidrosis is a rare disorder of the autonomic nervous system. It has been reported in association with peripheral nerve, spinal cord and cerebral lesions, and in some cases the etiology is unknown.
