RESUMO
Cellular asymmetry is an important element of efficiency in the compartmentalization of intracellular chemical reactions that ensure efficient tissue function. Improving the current 3D printing methods by using cellular asymmetry is essential in producing complex tissues and organs such as the liver. The use of cell spots containing at least two cells and basement membrane-like bio support materials allows cells to be tethered at two points on the basement membrane and with another cell in order to maintain cell asymmetry. Our model is a new type of 3D bioprinter that uses oriented multicellular complexes with cellular asymmetry. This novel approach is necessary to replace the sequential and slow processes of organogenesis with rapid methods of growth and 3D organ printing. The use of the extracellular matrix in the process of bioprinting with cells allows one to preserve the cellular asymmetry in the 3D printing process and thus preserve the compartmentalization of biological processes and metabolic efficiency.
Assuntos
Bioimpressão , Alicerces Teciduais , Alicerces Teciduais/química , Engenharia Tecidual , Impressão Tridimensional , Hepatócitos , FígadoRESUMO
In this study, the fatigue usage factors for Findley and Matake stress-based criteria were determined in the case of an MK5×2 mine hoist drum brake system subjected to cyclic maneuver braking. The study was conducted for this type of brake system, because the majority of mine hoists in Romanian mines are equipped with this brake type, being in operation for several decades. A geometric model of the brake was built using SolidWorks and imported in COMSOL Multiphysics to perform thermo-mechanical simulations. Based on the deformations and von Mises stresses determined by the thermomechanical simulation and, considering the calculated endurance limits of the brake system materials, Matake and Findley fatigue life evaluation simulations from COMSOL's fatigue module were conducted. The results show that the highest fatigue is expected on the drum lining surface towards the exit point from under the brake shoe in both cases, and the values of the usage factor of 0.307 (Findley) and 0.401 (Matake) are both under the critical value 1, meaning that the stress limit has not been exceeded for the brake system components and, thus, failure is not expected. Simulations were conducted considering an estimated 1.06 × 105 cycles during one year, more than both the usual service/replacement interval of the friction components of the brake, and the period of mandatory technical inspections imposed by regulations.
RESUMO
This paper studies both the thermal and mechanical behavior of brake system models in the case of the emergency braking of a mine hoist model. Using a step-by-step approach inspired by studies conducted on small brake systems with high rotation speeds specific to road and rail vehicles, a comparative analysis using a computer simulation was performed for the two types of brakes of a mine hoist system. A Solidworks model was built for two configurations: the drum-and-shoe and the disc-and-pads, and it was imported to COMSOL Multiphysics, where the material properties and simulation parameters were defined. Simulations were performed for each configuration, first using a Heat transfer module in the solids to investigate the frictional heat. The results showed the locations of the hot points on the disc and on the drum, with the surface temperature reaching 97 °C on the disc and 115 to 159 °C on the drum. Next, simulations using a Structural Mechanics module were run to obtain the stress and deformation induced by the heat generated during braking. The von Mises stress of the drum-and-shoe brake occurred on the external surface of the drum and had a value of 2 × 108 N/m2. For the disc-and-pad brake, the stress occurred towards the edges of the brake pad contact and was 4 × 108 N/m2. Both values were under the yield stress of the passive brake element material. Regarding the deformations, for the drum-and-shoe brake, it appeared towards the outer boundary of the drum, being 0.45 mm, and for the disc-and-pad brake, it was situated at the external edge of the disc, being 0.25 mm. COMSOL Multiphysics allowed the evaluation of the thermo-mechanical behavior using noninvasive techniques since actual emergency braking testing on a working mine hoisting installation is not possible because of safety and logistic concerns.
RESUMO
Breakdown of stackers and excavators in opencast mines is possible because of operating, manufacturing and structural causes, and it produces high financial losses. These can be prevented by using various measures, including analyses and strength tests, with computerized modeling and simulation using FEA or other techniques being implemented in the recent years. In this paper a fatigue study is conducted on the boom of a BWE. Based on a computer model of the boom previously developed in SOLIDWORKS by our author team, first the modal analysis is conducted for three positions of the boom by studying the frequency response during the excavation process. This is followed by the time response determination corresponding to the maximum displacement frequency, in order to assess the stress during the excavation process, which causes the material fatigue in the boom structure. It was found that the maximum displacements appear when the BWE boom operates in a horizontal position. The aim was to estimate the period of time to failure in order to prevent unwanted accidents, and to develop a method that is applicable to any surface mining or industrial machine with similar structure.