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1.
ACS Appl Bio Mater ; 7(7): 4593-4601, 2024 Jul 15.
Artigo em Inglês | MEDLINE | ID: mdl-38914048

RESUMO

Protein-based ultrafine fibrous scaffolds can mimic the native extracellular matrices (ECMs) with regard to the morphology and chemical composition but suffer from poor mechanical and wet stability. As a result, cells cannot get a true three-dimensional (3D) environment as they find in native ECMs. In this study, an epoxide, ethylene glycol diglycidylether (EGDE), with high reactivity to active hydrogen is introduced to gelatin solution, serving as an effective cross-linker. The gelatin/EGDE 3D-ultrafine (∼500 nm in diameter) fibrous composite scaffolds are made by an ultralow-concentration phase separation technique (ULCPS). The effects of the polymer content and modification conditions on the morphology and wet stability of the constructs are investigated. It is revealed that ultrafine fibers with 3D random orientation could be formed at low concentrations (0.01, 0.05, and 0.1 wt %, respectively). The wet stability of the constructs could be effectively improved by introducing EGDE into the gelatin system. The shrinkage is reduced to merely 2.14% after the modification at 120 °C for 2 h and could be maintained for up to 3 days. In order to improve the compression properties, the same technique is utilized with the presence of a poly(lactic acid) (PLA) spacer fabric to produce a bicomponent scaffold. The mechanical property and cell viability of the bicomponent scaffolds are investigated, and it is found that cells could enter deep inside and orient themselves randomly at the central area of the bicomponent scaffold. The modification and design approach presented in this study has the potential to provide various protein-based ultrafine fibrous biomaterials for a variety of biomedical applications.


Assuntos
Materiais Biocompatíveis , Gelatina , Teste de Materiais , Tamanho da Partícula , Engenharia Tecidual , Alicerces Teciduais , Gelatina/química , Alicerces Teciduais/química , Materiais Biocompatíveis/química , Materiais Biocompatíveis/farmacologia , Materiais Biocompatíveis/síntese química , Animais , Compostos de Epóxi/química , Sobrevivência Celular/efeitos dos fármacos , Camundongos , Humanos
2.
Heliyon ; 10(7): e29170, 2024 Apr 15.
Artigo em Inglês | MEDLINE | ID: mdl-38623225

RESUMO

The increasing depletion of reserves of natural resources has led to a growing worldwide focus on the exploitation of available waste in new domains. The presence of weedy plants is pervasive on a global scale and has detrimental effects on several aspects of the environment, agriculture, and people's health. Therefore, repurposing these Agri-weed plants for beneficial purposes would be a significant achievement. Furthermore, since raw materials constitute a substantial portion of manufacturing costs, using weeds as a feasible substitute for raw materials might potentially provide considerable advantages for manufacturers. In this study, an endeavor has been made to the utilization of agricultural waste "Urena Lobata", for the purpose of paper production. In the interim, the utilization of Urena Lobata as an alternative and sustainable raw material for pulp and paper industry could potentially offer a beneficial approach to mitigation of deforestation. The effective production of handsheets with weights of 70 g/m2 and 80 g/m2 was achieved using Urena Lobata fiber, Bleached Urena Lobata Fiber, and hardwood kraft pulp. Mechanical characteristics of handsheet's were comprehensively examined by the bursting index, tensile strength, tear index, brightness percentage and scanning electron microscope for handsheet's morphology. The results show that the handsheets produced by Urena Lobata fiber exhibit a much lower brightness percentage, high tensile strength and bursting index. Alongside, handsheets by bleached Urena Lobata fiber indicate higher brightness percentage, satisfactory values for tensile strength, bursting index, and tear index. The prepared materials are suitable for a broad spectrum of prospective applications, encompassing newsprint, tissue paper, filtration paper as well as high-quality writing and printing paper.

3.
Heliyon ; 9(3): e13639, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36895352

RESUMO

Cotton-wrapped elastane core yarns have been widely used in producing stretch denim fabrics due to their comfortable stretching and recovery, but they suffer from undesirable fabric growth under prolonged or repeated stress. To reduce that problem, an additional semi-elastic multifilament has been incorporated with the elastane core, called dual-core yarn. Herein, it was intended to produce well-engineered dual-core yarns possessing high elasticity with low bagging. Twenty types of cotton-wrapped elastane/T400 multifilament dual-core yarns with different combinations of elastane and T400 tension draft were produced on industrial scale in a spinning mill. Structural parameters, tensile properties and elastic recovery behavior under cyclic loading of the yarns were thoroughly studied. For an optimum combination of elastane/T400 draft, the dual-core yarn attained excellent tenacity and elongation with significantly low evenness, imperfections and hairiness values. More importantly, the results of the cyclic loading study explicitly revealed a remarkable reduction in plastic deformation and stress decay indicating low growth and high resilience of yarn after deformation. The dual-core yarn containing high strength, high elongation and low growth obtained here can have durable stretch jeans with high body movement comfort and long-lasting shape retention.

4.
Heliyon ; 8(8): e10055, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-35992009

RESUMO

Since the reserves of natural renewable resources are being inexorably diminished, the utilization of the recoverable waste in new area is gaining global attention day by day. Besides, as the cost of raw materials constitutes the majority of a production cost, the usage of undesirable but inevitable processing waste in the manufacturing process provides a considerable advantage to the manufacturers. Herein, it has been attempted to exploit unusable cotton spinning mill waste (filter waste derived from humidification plant) to convert it into paper. Handsheets of 70 g/m2 and 80 g/m2 were successfully produced from 100% cotton waste, 100% bleached cotton waste, and blends of bleached cotton waste with bleached hardwood kraft pulp (HWKP) (HWKP is typically used to produce commercial-grade papers). Morphologies and mechanical properties of handsheets were thoroughly investigated by whiteness index, brightness%, breaking length, tear index, bursting index, FTIR spectroscopy, optical microscope, and scanning electron microscope. Based on detailed observations, it is summarized that the produced handsheets, depending on the chemical treatment and blend ratio with HWKP, possess variations in appearances and properties that will have a wide range of potential applications from newsprint, tissue paper to commercial-grade writing and printing papers.

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