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Curr Mol Pharmacol ; 15(1): 51-76, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-34515018

RESUMO

Sports deserve a special place in human life to impart healthy and refreshing wellbeing. However, sports activities, especially contact sports, renders athlete vulnerable to brain injuries. Athletes participating in a contact sport like boxing, rugby, American football, wrestling, and basketball are exposed to traumatic brain injuries (TBI) or concussions. The acute and chronic nature of these heterogeneous injuries provides a spectrum of dysfunctions that alters the neuronal, musculoskeletal, and behavioral responses of an athlete. Many sports-related brain injuries go unreported, but these head impacts trigger neurometabolic disruptions that contribute to long-term neuronal impairment. The pathophysiology of post-concussion and its underlying mechanisms are undergoing intense research. It also shed light on chronic disorders like Parkinson's disease, Alzheimer's disease, and dementia. In this review, we examined post-concussion neurobehavioral changes, tools for early detection of signs, and their impact on the athlete. Further, we discussed the role of nutritional supplements in ameliorating neuropsychiatric diseases in athletes.


Assuntos
Traumatismos em Atletas , Concussão Encefálica , Futebol Americano , Atletas , Traumatismos em Atletas/psicologia , Concussão Encefálica/complicações , Concussão Encefálica/psicologia , Futebol Americano/lesões , Humanos
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