[National guidelines of diagnosis and treatment of the non-Hodgkin lymphoma]. / Guías nacionales de diagnóstico y tratamiento de linfoma no Hodgkin.

Non-Hodgkin lymphoma comprises a heterogeneous group of haematological malignancies, classified according to their clinic, anatomic-pathological features and, lately, to their molecular biomarkers. Despite the therapeutic advances, nearly half of the patients will die because of this disease. The new diagnostic tools have been the cornerstone to design recent therapy targets, which must be included in the current treatment guidelines of this sort of neoplasms by means of clinical trials and evidence-based medicine. In the face of poor diagnoses devices in most of the Mexican hospitals, we recommend the present diagnose stratification, and treatment guidelines for non-Hodgkin lymphoma, based on evidence. They include the latest and most innovative therapeutic approaches, as well as specific recommendations for hospitals with limited framework and therapy resources.

[Cystic neoplasm of the pancreas: a ten years experience]. / Tumores quísticos de páncreas. Informe de 10 años.

BACKGROUND: Pancreatic cystic lesions (PCL) are identified in 1 % of patients who undergo abdominal computed tomography scans, because it is difficult to discriminate clinically between benign and malignant PCL. The PCL must be distinguished from inflammatory pseudocysts, which can have a similar radiographic appearance. The aim of this study was to review the incidence of PCL during 10 years. METHODS: Nineteen consecutive patients who underwent surgical resection of a cystic lesion of the pancreas during a 10-year period were reviewed. RESULTS: From 1998, 434 patients underwent to pancreatic surgery, 103 (25.75%) resulted with neoplasm of the pancreas and a PCL was diagnosed in 19 of them (18.44%). They were more common in women (n=15, 79%). The pathologic diagnosis was mucinous cystadenoma (n=6, 31.5%) followed by serous cystadenoma and solid cystic papilar tumor (n=4, 21%). Mucinous cystadenocarcinoma was diagnosed in a 77 year-old man and a serous cystadenocarcinoma was diagnosed in a 53 years-old woman; cystic degeneration of two insulinomas were diagnosed in a 71 year-old woman and a 32 year-old man (5.26%). CONCLUSIONS: PCLs represent a spectrum of associated diseases. The incidence of serous cystadenoma is lower in our experience.

[Frantz-Gruber tumor: a case report]. / Tumor de Frantz-Gruber: reporte de un caso.

OBJECTIVE: The objective of this report is to describe the existence of a rare tumor that must be taken into consideration when studying the diagnosis of pancreatic tumors. CASE REPORT: A 20-year-old female with abdominal pain as an only manifestation was seen. The diagnosis of a pancreatic head and body tumor was made. During surgery, we found a tumor in the head and body of the pancreas that measured approximately 10 x 7 cm; histopathologic study revealed a solid and cystic papillary epithelial neoplasm of the pancreas. DISCUSSION: Frantz-Gruber tumor is a rare pancreatic tumor suspected during the evaluation of a young female with abdominal pain and confirmed during surgery. It is important to consider the existence of this tumor in the evaluation of patients with these characteristics; even if the tumor's biological behavior is benign Frantz-Gruber tumor is considered a low-grade malignant tumor

[Chronic invasive rhinocerebral mucormycosis]. / Mucormicosis rinocerebral invasora crónica.

Rhinocerebral mucormycosis is a fulminant fungal disease that typically presents acutely in patients with diabetic ketoacidosis or immunosuppression. The case of a 55 year-old male patient is presented; the patient experienced chronic infection that involved nose, paranasal sinuses, hard palate, orbit, pterygopalatine fossa, infratemporal fossa with cavernous sinus thrombosis and compression of the internal carotid artery which develops in insidious manner after metabolic imbalance with predominantly ocular symptoms. The patient was managed with Amphotericin B and radical surgical debridement of affected tissue, the patient presenting cure without complications or added disabilities.

[Perianal leukemic infiltration. Case report]. / Infiltración leucémica perianal. Informe de un caso.

BACKGROUND: Leukemic infiltration of perianal skin (leukemia cutis) is quite uncommon, and may consist of no diffuse infiltration, erythema, ulceration, fistula, and abscess. Diagnosis may be established by biopsy and adequate hematologic studies. Treatment must be conservative in patients with poorly controlled disease (sitz baths, antibiotics, radiotherapy), and surgical in patients with risk of fulminant sepsis and death. OBJECTIVE: To report a case of leukemic perianal infiltration with atypical ulcerated lesion. CASE REPORT: Female patient, 21 years of age with diagnosis of AML M7, began with perianal pain posterior to evacuation associated with bleeding; at perianal examination we found anterior atypical ulcerated lesion. We carried out a biopsy under suspicion of leukemic infiltration corroborated by histopathology. The patient received conservative treatment. CONCLUSIONS: We must suspect leukemic infiltration in patients with anal symptoms and effect close surveillance. Prognosis depends on control of hematologic disease.

Enfermedad de Hogkin primaria de bazo: presentación de un caso clínico / Spleen primary Hodgkin disease: a report of a case

En este reporte se comunica el caso de un paciente con una infrecuente manifestación de la enfermedad de Hodgkin. Era un varón con antecedentes de alcoholismo crónico que sufría pancitopenia, derrame pleural y gran esplenomegalia. Al principio se pensó en cirrosis hepática con hiperesplenismo; sin embargo, debido a que no hubo datos de afección hepática y la anemia persistía a pesar de las hemotransfusiones, se decidió la esplenectomía. El estudio histopatológico reveló enfermedad de Hodgkin de variedad celularidad mixta. Más adelante se realizó una biopsia de hueso en la que se encontraron células neoplásicas similares a las encontradas en el bazo. En la revisión de la literatura sólo se identificaron reportes aislados.