RESUMO
AIM: To investigate the effect of C-reactive protein (CRP) expression in type 2 diabetes mellitus (T2DM) complicated with vascular lesions and its clinical significance. METHODS: 90 cases of T2DM patients were divided into vascular disease group (observation group, 45 cases) and non-vascular lesion group (control group, 45 cases), the CRP, FPG, HbAlc, TC, LDL-C and HDL-C levels of the two groups were measured, the blood pressure and BMI were recorded. RESULTS: (1) The serum CRP concentration and blood pressure levels of the observation group were higher than the control group, compared with the difference was significant (P<0.05), and the FPG levels and HbAlc values of the two groups were no significantly difference (P>0.05). (2) The serum TG, Fins level and BMI of the observation group were higher than the control group, compared with the difference was significant (P<0.05), and the HDL-C and LDL-C levels of the two groups were no significantly difference. CONCLUSION: The serum CRP combine with the blood pressure, blood lipids, body weight and insulin indicators has important clinical significance for early diagnosis, prevention, treatment and prognosis of T2DM complication with vascular lesions.
