RESUMO
Solid organ transplantation is becoming increasingly common in the treatment of end-stage organ failure. However, despite improvements in patient and allograft survival, immunosuppression-induced compromised cell-mediated immunity predisposes transplant recipients to opportunistic infections. We describe a case of mixed opportunistic lung infection in the form of cytomegalovirus pneumonia and mucormycosis in a renal transplant recipient. Prompt recognition and treatment of infection is imperative for successful transplantation.
Assuntos
Infecções por Citomegalovirus/complicações , Pneumopatias Fúngicas/complicações , Mucormicose/complicações , Infecções Oportunistas/complicações , Pneumonia Viral/complicações , Adulto , Infecções por Citomegalovirus/patologia , Humanos , Imunossupressores/efeitos adversos , Transplante de Rim , Pneumopatias Fúngicas/patologia , Masculino , Mucormicose/patologia , Infecções Oportunistas/patologia , Pneumonia Viral/patologiaRESUMO
Sirenomelia is a rare and interesting congenital anomaly where there is fusion of the lower limb buds in association with a number of other anomalies, together termed as the caudal regression syndrome. We report this syndrome in a male foetus of 33 weeks gestational age, and review its embryological basis.
Assuntos
Ectromelia/patologia , Anormalidades Múltiplas/embriologia , Anormalidades Múltiplas/patologia , Adulto , Ectromelia/embriologia , Feminino , Feto/patologia , Humanos , Rim/anormalidades , Masculino , GravidezRESUMO
The distribution and abundance of mast cells was studied in 110 nasal non- neoplastic polypoidal lesions. In most of the polyps of all kinds, the epithelium showed less than 5000 mast cells/mm(1). Out of the 72 so- called "nonallergic polyps", 29 (40,3%) showed more than 20,000 mast cells/mm(1) in the subepithelial layer, and 30 (41.7%) more than 20,000 mast cells/mm(1) in the deeper areas. Out of the 18 so- called "allergic polyps", 8 (44.5%) showed more than 20,000 mast cells/ mm(3) in the subepithelial layer, and, 8 (44.5%) more than 20,000 mast cells/mm(3) in the deeper areas. Interestingly, mast cells were also seen in very high numbers in 33-38% of cases of chronic hypertrophic rhinitis, rhinosporidiosis and mucormycosis. There was no correlation between the proportion of eosinophils and mast cells in the lesions. We conclude that mast cells are not restricted to allergic nasal lesions and the significance of their presence in nasal lesions needs to be evaluated.
RESUMO
A rare case of sclerosing mediastinitis in a 38 year old male is described. This interesting case illustrates how a seemingly benign fibrosing condition may lead to disastrous and fatal complications.