Further caries decline in Swiss recruits from 1996 to 2006.

Previous investigations showed a steady decline of the caries experience. The purpose of this study was to determine the caries experience of Swiss recruits in 2006 and to compare it to that of 1985 and 1996. The results of a parallel investigation which dealt with the periodontal health of the same recruits have already been published (Röthlisberger et al. 2007). Investigations on recruits in 1970 (Curilovic et al. 1972) and 1974 (Curilovic et al. 1980) used another methodology. Therefore, they were not included here for comparison.

Pathogenesis of sialadenosis: possible role of functionally deficient myoepithelial cells.

OBJECTIVES: The pathogenesis of acinar enlargement in sialadenosis is obscure. As myoepithelial cells had been reported to show degenerative changes, we decided to investigate the possible role of functionally deficient myoepithelial cells in the development of sialadenosis. STUDY DESIGN: This study was a morphometric analysis of glands immunohistochemically stained for CK14, alpha-actin, and Ki67 in 10 cases of sialadenosis and 11 normal parotids. RESULTS: In sialadenosis, acini were much larger; there was a minor decrease in the density of the distribution of myoepithelial cells stained for CK14 and a major decrease in the density of the distribution and thickness of the myofilament component of myoepithelial cells stained for alpha-actin; and the proliferation of acinar and myoepithelial cells was reduced. CONCLUSIONS: Our results demonstrate a major loss and thinning of the myofilament component of the myoepithelial cells and thereby a loss of mechanical support for the acini in sialadenosis. This possibly allows acinar cells to expand as secretory granules accumulate intracellularly to produce the great acinar enlargement. This functional myoepithelial insufficiency is possibly a consequence of an autonomic neuropathy secondary to severe metabolic or hormonal disorders.

The impact of the stone age diet on gingival conditions in the absence of oral hygiene.

BACKGROUND: The objective of this study was to assess the oral microbiota and clinical data in subjects without access to traditional oral hygiene methods and who ate a diet available in the Stone Age. METHODS: Ten subjects living in an environment replicating the Stone Age for 4 weeks were enrolled in this study. Bleeding on probing (BOP), gingival and plaque indices, and probing depth (PD) were assessed at baseline and at 4 weeks. Microbiologic samples were collected at the mesio-buccal subgingival aspects of all teeth and from the dorsum of the tongue and were processed by checkerboard DNA-DNA hybridization methods. RESULTS: No subject had periodontitis. Mean BOP decreased from 34.8% to 12.6% (P <0.001). Mean gingival index scores changed from 0.38 to 0.43 (not statistically significant) and mean plaque scores increased from 0.68 to 1.47 (P <0.001). PD at sites of subgingival sampling decreased (mean difference: 0.2 mm; P <0.001). At week 4, the total bacterial count was higher (P <0.001) for 24 of 74 species, including Bacteroides ureolyticus, Eikenella corrodens, Lactobacillus acidophilus, Capnocytophaga ochracea, Escherichia coli, Fusobacterium nucleatum naviforme, Haemophilus influenzae, Helicobacter pylori, Porphyromonas endodontalis, Staphylococcus aureus (two strains), Streptococcus agalactiae, Streptococcus anginosis, and Streptococcus mitis. Bacterial counts from tongue samples were higher at baseline (P <0.001) for 20 species, including Tannerella forsythia (previously T. forsythensis), Aggregatibacter actinomycetemcomitans (previously Actinobacillus actinomycetemcomitans; serotype a), and Streptococcus spp. CONCLUSIONS: The experimental gingivitis protocol is not applicable if the diet (e.g., Stone Age) does not include refined sugars. Although plaque levels increased, BOP and PD decreased. Subgingival bacterial counts increased for several species not linked to periodontitis, whereas tongue bacterial samples decreased during the study period.

[Dry mouth--oral care for patients with oligoliasia and xerostomia]. / Mundtrockenheit--Ursachen, Diagnose und Betreuung von Patienten mit Oligosialie oder Xerostomie.

Reduced flow (oligosialia) or the complete absence of saliva (xerostomia) decrease the quality of life. While patients suffering from xerostomia are painfully aware of their condition, oligosialia all too often remains unnoticed. The causes of reduced saliva flow are manyfold: somatic or psychosomatic disease, medication, medical therapy, dehydration, age, to name a few. The respective patients suffer from thirst, difficulties in speaking (dysphonia), chewing, tasting (dysgeusia), swallowing (dysphagia) and are at a very high risk for caries as well as for bacterial, viral or fungal infections of the oral mucosa. Early diagnosis and care of oligosialia is mandatory Oral prophylactic care for and dental therapy of xerostomic patients are challenging both for the patients and the dental professionals.