RESUMO
Romiplostim is a thrombopoietin receptor agonist that increases platelet counts and restores platelet function in patients with chronic immune thrombocytopenia (ITP). Increase in platelet count and platelet activation has been associated with increased thromboembolic risk. The present case report describes an interesting case of acute stent thrombosis in a patient with chronic immune thrombocytopenic purpura (ITP) being treated with romiplostim.
Assuntos
Contagem de Plaquetas , Púrpura Trombocitopênica Idiopática/tratamento farmacológico , Receptores de Trombopoetina/agonistas , Stents , Trombose/induzido quimicamente , Doença Aguda , Aspirina/uso terapêutico , Dor no Peito , Clopidogrel , Eptifibatida , Feminino , Humanos , Pessoa de Meia-Idade , Peptídeos/uso terapêutico , Piperazinas/uso terapêutico , Inibidores da Agregação Plaquetária/uso terapêutico , Cloridrato de Prasugrel , Receptores de Trombopoetina/biossíntese , Fatores de Risco , Tiofenos/uso terapêutico , Ticlopidina/análogos & derivados , Ticlopidina/uso terapêutico , Ultrassonografia de IntervençãoAssuntos
Dissecção Aórtica/diagnóstico por imagem , Aneurisma Coronário/diagnóstico por imagem , Complicações Cardiovasculares na Gravidez/diagnóstico por imagem , Adulto , Dissecção Aórtica/cirurgia , Aneurisma Coronário/cirurgia , Vasos Coronários/patologia , Vasos Coronários/cirurgia , Feminino , Humanos , Gravidez , Complicações Cardiovasculares na Gravidez/cirurgia , RadiografiaRESUMO
Optical coherence tomography (OCT) is a novel imaging modality in interventional cardiology. With its clear image quality, it has attracted considerable attention as a tool to accurately evaluate atherosclerosis and coronary stents in vivo. It has a 10-fold higher resolution compared to intravascular ultrasound and utilises near-infrared light that requires temporary blood clearance during image acquisition. We present a case of in-stent restenosis in a patient five years after percutaneous intervention. Optical coherence tomography clearly showed the mechanism behind the stent failure and helped appropriately plan the subsequent repeat intervention. The technology heralds an exciting advance in the invasive assessment of the coronary arteries that will improve our understanding of heart disease into the future.
