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1.
Pediatr Blood Cancer ; 63(3): 398-405, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26536284

RESUMO

The utility of radiosurgery for pediatric brain tumors is not well known. For children, radiosurgery may have an important role for treating unresectable tumors, residual disease, or tumors in the recurrent setting that have received prior radiotherapy. The available evidence demonstrates utility for some children with primary brain tumors resulting in good local control. Radiosurgery can be considered for limited residual disease or focal recurrences. However, the potential toxicities are unique and not insignificant. Therefore, prospective studies need to be performed to develop guidelines for indications and treatment for children and reduce toxicity in this population.


Assuntos
Neoplasias Encefálicas/cirurgia , Radiocirurgia , Adolescente , Craniofaringioma/cirurgia , Ependimoma/cirurgia , Glioma/cirurgia , Humanos , Meduloblastoma/cirurgia , Complicações Pós-Operatórias , Resultado do Tratamento
2.
Neuromodulation ; 17(7): 670-6; discussion 676-7, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-24512097

RESUMO

OBJECTIVES: Percutaneous spinal cord stimulation electrodes have a propensity to migrate longitudinally, which is a costly complication that often compromises therapeutic effect. After implementing simple changes to our percutaneous electrode anchoring technique, we no longer encounter this migration. The current retrospective study updates previously reported results. MATERIALS AND METHODS: We retrospectively examined data in a consecutive series of patients in whom we had secured a new percutaneous electrode by injecting < 0.1 cm(3) of adhesive into the silicone elastomer lead anchor. From 1998 through 2006, we used whichever anchor was supplied with each lead until we observed one case of migration through a short anchor; thereafter, we used a long, tapered anchor exclusively. From 2007 through 2013, we further modified our technique by adding a fascial incision to accommodate the tip of the anchor and by increasing the strength of our suture material. RESULTS: In the first series of 291 patients, followed through July 2007 (mean 4.75 years, range 1.1-9.0 years), 4 (1.37%) experienced electrode migration requiring surgical revision. Only one lead had moved with respect to its anchor; the other three anchors remained securely bonded to their leads. No migration (0.00%) occurred in the second series of 142 patients, followed through 2013 (mean follow-up 2.86 years, range 0.10-5.45 years). CONCLUSION: Improvements to our simple, inexpensive technique apparently have eliminated the most common complication of spinal cord stimulation.


Assuntos
Eletrodos Implantados/efeitos adversos , Migração de Corpo Estranho/etiologia , Migração de Corpo Estranho/prevenção & controle , Pele/inervação , Estimulação da Medula Espinal/efeitos adversos , Idoso , Feminino , Humanos , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos
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