1.
J Org Chem
; 76(10): 4132-8, 2011 May 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-21520957
RESUMO
A one-pot, three-step strategy for the regioselective semihydrogenation of dienes is described. This procedure uses 9-BBN-H as a temporary protective group for alkenes. Yields range from 55% to 95%, and the reaction is tolerant of a variety of common functional groups. Additionally, the final elimination step of the sequence can be replaced with a peroxide-mediated alkylborane oxidation, generating regioselectively semihydrogenated product alcohols.