RESUMO
Development and selection of an ideal scaffold is of importance for tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a biocompatible bioresorbable copolymer that belongs to the polyhydroxyalkanoate family. Because of its good biocompatibility, PHBHHx has been widely used as a cell scaffold for tissue engineering. This review focuses on the utilization of PHBHHx-based scaffolds in tissue engineering. Advances in the preparation, modification, and application of PHBHHx scaffolds are discussed.
Assuntos
Ácido 3-Hidroxibutírico/química , Materiais Biocompatíveis/química , Caproatos/química , Engenharia Tecidual/métodos , Alicerces Teciduais/química , Ácido 3-Hidroxibutírico/uso terapêutico , Materiais Biocompatíveis/uso terapêutico , Osso e Ossos/fisiologia , Caproatos/uso terapêutico , Cartilagem/fisiologia , Liofilização , Humanos , Músculo Liso/fisiologia , Regeneração , Propriedades de SuperfícieRESUMO
Development and selection of an ideal scaffold is of importance for tissue engineering. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBHHx) is a biocompatible bioresorbable copolymer that belongs to the polyhydroxyalkanoate family. Because of its good biocompatibility, PHBHHx has been widely used as a cell scaffold for tissue engineering. This review focuses on the utilization of PHBHHx-based scaffolds in tissue engineering. Advances in the preparation, modification, and application of PHBHHx scaffolds are discussed.