A review of quantification methods for light absorption enhancement of black carbon aerosol.

Black carbon (BC) is a distinct type of carbonaceous aerosol that has a significant impact on the environment, human health, and climate. A non-BC material coating on BC can alter the mixing state of the BC particles, which considerably enhances the mass absorption efficiency of BC by directing more energy toward the BC cores (lensing effect). A lot of methods have been reported for quantifying the enhancement factor (Eabs), with diverse results. However, to the best of our knowledge, a comprehensive review specific to the quantification methods for Eabs has not been systematically performed, which is unfavorable for the evaluation of obtained results and subsequent radiative forcing. In this review, quantification methods are divided into two broad categories, direct and indirect, depending on whether experimental removal of the coating layer from an aged carbonaceous particle is required. The direct methods described include thermal peeling, solvent dissolution, and optical virtual exfoliation, while the indirect methods include intercept-linear regression fitting, minimum R squared, numerical simulation, and empirical value. We summarized the principles, procedures, virtues, and limitations of the major Eabs quantification methods and analyzed the current problems in the determination of Eabs. We pointed out what breakthroughs are needed to improve or innovate Eabs quantification methods, particularly regarding the need to avoid the influence of brown carbon, develop a broadband Eabs quantification scheme, quantify the Eabs values for the emissions of low-efficiency combustions, measure the Eabs of particles in a high-humidity environment, design a real-time monitor of Eabs by a proper combination of mature techniques, and make more use of artificial intelligence for better Eabs quantification. This review deepens the understanding of Eabs quantification methods and benefits the estimation of the contribution of BC to radiative forcing using climate models.

Does internet use benefit the mental health of older adults? Empirical evidence from the China health and retirement longitudinal study.

The mental health (MH) of older adults is a prominent public health concern. However, research regarding the impact of emerging Internet use on MH among older adults remains limited, particularly in transitional economies experiencing a rapidly aging population such as China. Thus, to address this research gap, this study uses data from the 2013-2018 waves of the China Health and Retirement Longitudinal Study. To investigate the causal relationship between Internet use and MH among older adults and explore the underlying channels through which this relationship operates. The results reveal a notable positive association between Internet use and MH among older adults. Furthermore, the study highlights social interaction, social trust, traveling expenses, and healthy habits as crucial channels through which Internet use can impact MH among older adults. The analysis also reveals how Internet use demonstrates a stronger positive effect on older individuals who have fewer chronic diseases and live with their offspring compared with their counterparts. These findings have significant policy implications, which thus emphasizes the need to enhance Internet use among older adults as a means of improving their MH.

Metabolome and transcriptome analyses provide new insights into the mechanisms underlying the enhancement of medicinal component content in the roots of Acanthopanax senticosus (Rupr. et Maxim.) Harms through foliar application of zinc fertilizer.

Acanthopanax senticosus (Rupr. et Maxim.) Harms is a perennial shrub of the Acanthopanax genus in the Araliaceae family and has a high medicinal value. The application of zinc fertilizer can improve the yield and quality of medicinal materials. However, there are limited reports on approaches to increase the content of medicinal components in A. senticosus, hindering the improvement of its medicinal quality. In this study, A. senticosus was treated with 0.1% (LZn) and 0.4% (HZn) zinc sprayed on the leaf surface. The effects of zinc treatment on the medicinal components in the roots of A. senticosus were analyzed by comprehensive metabolomics and transcriptomics analyses. A total of 316 metabolites were detected, with a prevailing occurrence of terpenoids and phenylpropanoids. We identified metabolites related to the medicinal components that were upregulated after Zn treatment, including 43 terpenoids, 19 phenylpropanoids, eight phenols, and three flavonoids. Combining differential gene expression and K-means analysis, we found 95, 65, and 25 upregulated genes related to phenylpropanoid biosynthesis, terpenoid biosynthesis, and flavonoid biosynthesis, respectively. Under different concentrations of Zn treatment, the upregulated metabolite biosynthesis-related genes and differentially expressed transcription factors varied. Pearson correlation network analysis revealed significant correlations among terpenoids, phenylpropanoids, flavonoids biosynthetic genes, and several transcription factors (ERFs, WRKYs, bHLHs, NACs, and MYBs). This study lays the foundation for understanding the metabolic processes in response to varying levels of zinc foliar spray and provides a theoretical basis for enhancing the efficiency of zinc fertilizer utilization in A. senticosus.

Selective Adsorptive Desulfurization with Alkaline-Earth Metal-Modified Zeolites in Oil in the Presence of Olefin.

Adsorptive desulfurization (ADS) was a hopeful method for deep desulfurization of oil in mild conditions. In this paper, based on the alkaline-earth (AE) metal-modified Y zeolite (AEY), synthesis, systematic characterization, ADS performance test, and analysis of related adsorption mechanisms were carried out. The crystal and pore structure of Y zeolite were not damaged after ion exchange of AE, while the amount of acid sites and the ratio of Lewis/Bronsted acid sites were both decreased. Although surface acid sites on zeolites were believed to be active sites for ADS, the performance test results showed that AEY adsorbents had rather good S adsorption capacity compared to NaY. Moreover, the S adsorption selectivity in the presence of hexene-1 in oil was also desirable for all AEY adsorbents. Based on these experimental results and previously proposed mechanisms for S-containing compound adsorption, a new adsorption mechanism was proposed for AEY, and this mechanism was further supported by the aid of DFT calculations. The good S-removal performance of AEY adsorbents as well as the new proposed adsorption mechanism may help people design and synthesize further improved S-compound adsorbents for ADS processes in an oil refinery.

Supported Ni Catalysts: Simple Vapor Deposition Preparation Method and Improved Catalytic Performance for Oxidative Dehydrogenation of Ethane.

Developing new methods of catalyst preparation is one of the most important tasks in the field of catalysis. A simple one-tube vapor deposition (VD) is provided in this paper for preparing the supported Ni catalyst. Ni(acac)2 was used as the Ni precursor. This preparation method was successfully applied to three types of catalytic supports, that is, Al2O3 and zeolites 5A and Hß. Varying Ni contents of less than 8 wt % can be obtained by employing different conditions. The Ni content, depending on different deposition conditions, was preliminarily explored. The catalytic performance for oxidative dehydrogenation of ethane (ODHE) was tested for the prepared Ni catalysts by the VD method. Several cases of catalytic tests showed that for the same Ni content, the VD-prepared Ni catalyst presented better performance for ODHE than the one prepared by a traditional impregnation method. Besides the improvement in catalytic performance, several advantages of our VD preparation method for catalysis are discussed.

Does forest farm carbon sink projects affect agricultural development? Evidence from a Quasi-experiment in China.

Forest Farm Carbon Sink (FFCS) projects are one of the effective ways to achieve carbon neutrality and mitigate global warming. Though the existing literature has widely discussed the effect of FFCS on the allocation of agricultural factors, such as land, labor employment structure and income structure, little is known about whether FFCS projects could have an effect on agricultural development. Based on the panel data of 140 counties in Sichuan province, China, from 2002 to 2018, we examined the causal effect on agricultural total factor productivity (TFP), and revealed their dynamic effect and underlying mechanisms. Propensity score matching and the difference in difference (PSM-DID) method were used to address the endogeneity problem of FFCS implementation. Results showed that FFCS projects increased agricultural TFP by 1.7%-2.4%. Health, saving and industrial structure were the important channels through which FFCS projects affect agricultural TFP. Our findings suggest that policies promoting FFCS projects can increase agricultural TFP while achieving environmental goals-a win-win situation.

Factors affecting the health-related quality of life among urban adults in Hangzhou City / 预防医学

Objective@#To investigate the health-related quality of life and its influencing factors among urban adults in Hangzhou City, so as to provide the evidence for formulation and assessment of health policy. @*Methods@#A total of 1 800 permanent residents at ages of 18 to 64 years were sampled from Gongshu and Xihu districts, Hangzhou City using a stratified cluster random sampling method from May to August 2022. The health-related quality of life was measured with the EuroQol five-dimensional questionnaire (EQ-5D-5L), and factors affecting health-related quality of life were identified with a Tobit regression model.@*Results@#A total of 1 624 valid questionnaires were recovered, with a response rate of 90.22%, and the respondents included 693 men (42.67%) and 931 women (57.33%). The proportions of difficulty in mobility, self-care, usual activities, pain/discomfort, and anxiety/depression were 1.23%, 0.43%, 0.74%, 11.15% and 8.56%, and the median (interquartile range) of health state utility value and EuroQol Visual Analogue Scale (EQ-VAS) score were 1 (0) and 90 (15) points, respectively. Female (β=-0.050), age of 45 to 64 years (β=-0.067) and development of chronic disease (one chronic disease: β=-0.036; two and more chronic diseases: β=-0.090) were factor affecting of health state utility values, and age of 35 to 44 years (β=-1.945) and 45 to 64 years (β=-3.459), unemployment (β=-1.913), development of chronic disease (one chronic disease: β=-3.444; two and more chronic diseases: β=-8.529), high-level physical activity (β=2.355) and overweight/obesity (β=-1.456) were factors affecting the EQ-VAS score. @*Conclusions @#The overall health related quality of life is relatively good among urban adults in Hangzhou City. Gender, age, employment, physical activity, presence of chronic diseases and overweight/obesity may be associated with health-related quality of life among urban adults in Hangzhou City.

Dark Side or Bright Side: The Impact of Alcohol Drinking on the Trust of Chinese Rural Residents.

Existing studies have explored the causal effect of social capital on harmful drinking, while the effect of drinking habits on trust is scant. In China, drinking rituals and drinking culture are considered important ways of promoting social interaction and trust, especially in rural areas where traditional culture is stronger. Based on a field survey in rural China in 2019, this paper explores the relationship between drinking habits and trust. First, we found a negative relationship between drinking habits and trust, indicating that those people who drink alcohol are more likely to have a lower trust. Second, we found significant heterogeneity in the effect of alcohol consumption on social trust across various groups. Specifically, the negative effects of alcohol consumption on trust were stronger for the females than for males; drinking alcohol did not reduce the level of trust among the Chinese Communist Party (CCP) in rural China; compared with the Han nationality, we found that the effect of drinking on trust was not significant for the ethnic minority. Third, we observed that the negative effects of alcohol consumption on trust had thresholds across age and income. Among people under 51, the risk of trust from drinking was greater than for those over 51; the negative effect of drinking on residents' trust was more obvious in low-income families, but not significant in the group with an annual household income of more than CNY 40,000. Our empirical study provides a deeper understanding of drinking culture in rural China from a dialectical perspective.

Nutrition Transition with Accelerating Urbanization? Empirical Evidence from Rural China.

Although rapid urbanization is often considered as one of the most important drivers for changing dietary patterns, little attention has been paid to rural areas despite the profound transformation they have undergone. Using longitudinal data from the China Health and Nutrition Survey (CHNS) for the period from 2004 to 2011, this study seeks to better understand the relationship between the urbanization of rural areas and dietary transition, with the focus on nutrition intake and dietary quality. Our results suggest that with increasing urbanization, rural residents tend to have on average lower calorie intakes but higher dietary quality. Specifically, increasing urbanization consistently reduces carbohydrate consumption and reduces fat consumption after a turning point; protein consumption first decreases and then increases after the turning point with increasing urbanization. Urbanization shows a significant and positive effect on the Healthy Eating Index (HEI). In addition to sociodemographic changes, we find that changing consumer preferences and knowledge serve as important determinants in explaining the dietary transition in rural China from 2004 to 2011. In our study, urbanization appears to positively affect rural residents' healthy food preferences and dietary knowledge. This study is a first attempt for better understanding the nutrition transition resulting from accelerating urbanization in rural China; several limitations and areas for future research have been highlighted.

Association analysis of miRNA-related genetic polymorphisms in miR-143/145 and KRAS with colorectal cancer susceptibility and survival.

BACKGROUND: There is accumulating evidence of aberrant expression of miR-143 and miR-145 and their target gene KRAS in colorectal cancer (CRC). We hypothesize that single nucleotide polymorphisms (SNPs) within or near mRNA-microRNA (miRNA) binding sites may affect miRNA/target gene interaction, resulting in differential mRNA/protein expression and promoting the development and progression of CRC. METHODS: We conducted a case-control study of 507 patients with CRC recruited from a tertiary hospital and 497 population-based controls to assess the association of genetic polymorphisms in miR-143/145 and the KRAS 3' untranslated region (3'UTR) with susceptibility to CRC and patients' survival. In addition, genetic variations of genomic regions located from 500 bp upstream to 500 bp downstream of the miR-143/miR-145 gene and the 3'UTR of KRAS were selected for analysis using the Haploview and HaploReg software. RESULTS: Using publicly available expression profiling data, we found that miR-143/145 and KRAS expression were all reduced in rectal cancer tissue compared with adjacent non-neoplastic large intestinal mucosa. The rs74693964 C/T variant located 65 bp downstream of miR-145 genomic regions was observed to be associated with susceptibility to CRC (adjusted odds ratio (OR): 2.414, 95% CI: 1.385-4.206). Cumulative effects of miR-143 and miR-145 on CRC risk were observed (Ptrend=0.03). Patients having CRC carrying variant genotype TT of KRAS rs712 had poorer survival (log-rank P=0.044, adjusted hazard ratio (HR): 4.328, 95% CI: 1.236-15.147). CONCLUSIONS: Our results indicate that miRNA-related polymorphisms in miR-143/145 and KRAS are likely to be deleterious and represent potential biomarkers for susceptibility to CRC and patients' survival.

MiR-30a suppresses clear cell renal cell carcinoma proliferation and metastasis by targeting LRP6.

Recently, the role of miR-30a in tumor development has attracted extensive attention. In this study, we aimed to elucidate the role of miR-30a and its associated target low-density lipoprotein receptor-related protein 6 (LRP6) in clear cell renal cell carcinoma (ccRCC) cells. Here, miR-30a was markedly down-regulated in ccRCC tissues and cells, and was correlated with the advanced TNM stage and poor prognosis. By contrast, LRP6 protein level was increased in ccRCC specimens and cell lines, and inversely correlated with miR-30a expression. Stable overexpression of miR-30a suppressed cell proliferation in vitro, impeded tumor growth in vivo, prevented migration and invasion, and triggered apoptosis of ccRCC cells. Also, over-expression of miR-30a in ccRCC cells promoted the expression of the epithelial marker E-cadherin and reduced the levels of mesenchymal markers. Mechanistically, the dual-luciferase reporter, RNA immunoprecipitation and western blot assays confirmed that miR-30a directly targeted the 3'-untranslated regions of LRP6 to inhibit its expression. Further, miR-30a-mediated effect was partially reversed by co-transfection with LRP6 plasmids or enhanced by silencing of LRP6. In conclusion, miR-30a exhibits effective antitumor properties by targeting LRP6 in proliferation and metastasis of ccRCC. This study could provide new insights into the treatment of ccRCC.

Toward a national emission inventory for the catering industry in China.

Catering oil fumes are a major hazard to human health. In particular, the typical Chinese cooking style is characterised by a high temperature frying process that produces high levels of cooking oil fumes. However, limited data relating to this sector mean that national emission inventory data specific to the catering service industry do not exist. To address above deficiency and thus to establish the inventory of a city, or a province, or even a country, a door-to-door survey campaign was launched in the Chinese cities of Heze and Linfen to determine the structure of local catering industries. Data revealed that the number of catering businesses per 104 people was 17 ± 4. Of these, 3.0 ± 1.4, 15.0 ± 1.4, and 82.0 ± 0.0% were classified as large, medium, and small enterprises, respectively. Furthermore, the installation rates of fume purifiers were 74 ± 13, 66 ± 9, and 51 ± 14% for large, medium, and small enterprises, respectively, with net removal efficiencies of 63 ± 11, 50 ± 7, and 31 ± 8%, respectively. This information was extrapolated across all provincial regions of China to construct a provincial and national emission inventory. In 2017, China's national catering industry released approximately 34 kt of volatile organic compounds (VOCs), 38 kt of particulate matter with a diameter less than 2.5 µm (PM2.5), 48 kt of particulate matter with a diameter less than 10 µm (PM10), 1 kt of black carbon (BC), and 27 kt of organic carbon (OC). A significant correlation was observed between vegetable oil consumption and emissions (e.g., for VOCs, y = 14.94 x + 76.50, R2 = 0.87, where y is VOCs emissions and x is vegetable oil consumption), indirectly corroborating the rationality of the inventory. Moreover, this correlation provides the potential for a dynamic inventory based on vegetable oil consumption. Future studies are proposed to address more influential factors to improve the reliability of the national inventory and refer to big data, rather than door-to-door investigation, to identify the amount of catering service businesses in a region.

Contamination assessment, health risk evaluation, and source identification of heavy metals in the soil-rice system of typical agricultural regions on the southeast coast of China.

To quantitatively assess heavy metal accumulation and potential ecological and human health risks as well as analyze the sources of metals in a typical soil-rice system located on the southeast coast of China, 120 topsoil samples and corresponding rice grain samples were collected across the study area. The concentrations of As, Cd, Pb, Cr, Hg, Zn, Cu, and Ni were analyzed. The results revealed that Hg, Cd, and Cu were the main pollutants in soils. Besides, according to geo-accumulation value of Hg, 18.3% of samples were at or above moderate contamination levels. Additionally, the soil was in moderate ecological risk from combined heavy metal pollution, and 49.7% and 27.0% of this risk could be attributed to Hg and Cd pollution, respectively, due to their high toxic-response factors. For the rice samples, Cd content showed the highest biological accumulation coefficient value (40.8%) in rice grains and was slightly greater than its maximum allowable value (MAV) (0.2 mg/kg) in 7.5% of samples, whereas the other metals were all lower than their corresponding MAVs. Heavy metal exposure (especially As exposure) via rice consumption causes significant carcinogenic and non-carcinogenic risks to adults, and non-carcinogenic risk to children, while the carcinogenic risk to children was at tolerable level. Greater rice consumption might be responsible for the greater health risk to adults than children. Natural sources (loaded heavily with Cr and Ni) such as lithogenic components and soil parent materials, agricultural activities (loaded heavily with Cd, Cu, and Zn), especially excessive use of pesticides and fertilizers, and industrial activities (loaded heavily with Hg, Pb, and As) including vehicle emissions, coal combustion, and those of the textile and chemical industries were identified as the main sources. Effective regulations should be enforced to guarantee the safety of farm produce and protect ecological and human health in the study area.

Does Dietary Diversity Reduce the Risk of Obesity? Empirical Evidence from Rural School Children in China.

Childhood and adolescence overweight and obesity have implications for both health consequences and economic burden. Although it has been an emerging public health problem for primary school children in rural China and the importance of the diet-health link has been stressed for many years, rigorous analysis of the dietary diversity and obesity among children is rare. To clarify this issue, this study provides a better understanding of the functional linkage between dietary diversity and obesity by analyzing data from nearly 8500 rural primary students (aged from 10 to 13 years old) covering three provinces in China. Our estimation results show that there is a significantly negative correlation between dietary diversity and the probability of being overweight among primary students. In particular, for subgroups with higher dietary diversity, the negative correlation between dietary diversity and the incidence of overweight or obesity is stronger, and the absolute value of the coefficient is greater. The results also suggest that the increase in the consumption frequency of all dietary categories can significantly lead to a lower proportion of overweight. Thus, we conclude that higher dietary diversity can help to lower the risk of overweight and obesity among primary school children, presumably through increasing the daily frequency of food intakes and developing a more diverse dietary pattern.

Clinicopathological characteristics and survival of malignant fibrous histiocytoma of the bone: A population-based study using the SEER database.

Malignant fibrous histiocytoma of the bone (MFH-B) is an extremely rare and aggressive malignancy. The clinicopathological characteristics and prognosis of patients with MFH-B have not been defined. We conducted a retrospective study using the data of all MFH-B patients from the Surveillance, Epidemiology and End Results (SEER) database between 1975 and 2016. Initially, the clinicopathological characteristics were described. The difference in prognosis between patients with MFH-B and those with osteosarcoma was compared using propensity score matching analysis. Then, the features affecting the prognosis of patients with MFH-B were further determined using Cox regression analysis. A total of 318 patients with MFH-B were identified. The median overall survival (mOS) of all 318 patients with MFH-B was 29.0 months. The 1-, 3-, 5-, and 10- year survival rates were 67.4%, 53.6%, 38.7%, and 28.7%, respectively. The multivariate Cox regression analysis showed that older age, distant metastases, and flat bone lesion were independent factors for worse prognosis, whereas surgery was an independent factor for favorable survival, and this intervention could decrease risk of death by 61% (HR = 0.39, 95% CI 0.28-0.54). Apart from this, the prognosis of patients with MFH-B was significantly worse than that of patients with osteosarcoma in both unmatched and matched cohorts. In conclusion, MFH-B is a rare malignant bone cancer, with relatively worse prognosis than osteosarcoma. Older age, distant metastases, flat bone lesion, and surgery were independently associated with prognosis. In order to understand this disease more thoroughly and accurately, more cases with adequate information are required in the future.

Dietary patterns and thyroid cancer: a case-control studyin Hangzhou residents / 预防医学

Objective @#To learn the association between dietary patterns and thyroid cancer in Hangzhou residents, and to provide evidence for thyroid cancer prevention.@*Methods@#The newly diagnosed patients with thyroid cancer in Zhejiang Cancer Hospital were selected as the case group, while the healthy population matched (1∶1) by gender, age and residence were selected from community as the control group. A questionnaire survey was conducted to obtain demographic characteristics, disease history, dietary intake, lifestyle and other information. The dietary patterns were established by factor analysis. The multivariate conditional logistic regression model was conducted to explore the relationship between different dietary patterns and thyroid cancer.@*Results@#A total of 258 pairs of cases and controls were recruited. Five dietary patterns were obtained, including vegetarian pattern, high-protein food pattern, salted vegetables and algae pattern, seafood and cereal pattern, as well as alcohol and tea pattern. The multivariate conditional logistic regression analysis suggested seafood and cereal pattern might reduce the risk of thyroid cancer (OR=0.286, 95%CI: 0.146-0.561).@*Conclusion@#More consumption of seafood and cereal may decrease the incidence of thyroid cancer.