RESUMO
The title compound, C13H16ClNO, contains a methyl-piperidine ring in the stable chair conformation. The mean plane of the twisted piperidine ring subtends a dihedral angle of 39.89â (7)° with that of the benzene ring. In the crystal, weak C-Hâ¯O inter-actions link the mol-ecules along the a-axis direction to form infinite mol-ecular chains. Hâ¯H inter-atomic inter-actions, C-Hâ¯O inter-molecular inter-actions and weak dispersive forces stabilize mol-ecular packing and form a supra-molecular network, as established by Hirshfeld surface analysis.
RESUMO
The title compound, C13H16ClNO2, crystallized with two independent mol-ecules in the asymmetric unit (A and B). The piperidinol ring in mol-ecule B is disordered over two positions with a site occupancy ratio of 0.667â (5):0.333â (5). In both mol-ecules these rings have a chair conformation, including the minor component in mol-ecule B. Their mean planes are inclined to the benzene ring by 45.57â (13)° in mol-ecule A, and by 50.5â (4)° for the major component of the piperidine ring in mol-ecule B. In the crystal, the individual mol-ecules are linked by O-Hâ¯O hydrogen bonds, forming chains of A and B mol-ecules along the [100] direction. The chains are inter-linked by C-Hâ¯O hydrogen bonds, forming ribbons.
RESUMO
The title compound, C13H14NO2F3, crystallises with two mol-ecules, A and B, in the asymmetric unit, with similar conformations. The dihedral angles between the piperidine and phenyl rings are 83.76â (2) and 75.23â (2)° in mol-ecules A and B, respectively. The bond-angle sums around the N atoms [359.1 and 359.7° for mol-ecules A and B, respectively] indicate sp (2) hybridization for these atoms. In the crystal, O-Hâ¯O hydrogen bonds link the mol-ecules into separate [100] chains of A and B mol-ecules. The chains are cross-linked by C-Hâ¯O inter-actions, generating alternating (001) sheets of A and B mol-ecules.
RESUMO
In the title compound, C13H17NO2, the dihedral angle between the planes of the piperidine and benzene rings is 51.7â (2)°. The bond-angle sum around the N atom [359.8â (3)°] indicates sp (2) hybridization of the atom. In the crystal, O-Hâ¯O hydrogen bonds link the mol-ecules, forming chains along [001].
RESUMO
In the title compound, 0.75C12H14ClNO2·0.25C12H14ClNO, which is an adduct comprising 0.75 4-hy-droxy-piperidin-1-yl or 0.25 4-piperidin-1-yl substituents on a common (4-chloro-phen-yl)methanone component; the dihedral angles between the benzene ring and the two piperidine rings are 51.6â (3) and 89.5â (7)°, respectively. The hy-droxy-piperidine ring is in a bis-ectional oriention (bi) with the phenyl ring. In the crystal, inter-molecular O-Hâ¯O hydrogen bonds between the hy-droxy-piperidine group and the keto O atom lead to the formation of chains extending along the c- axis direction.
RESUMO
The title compound, C22H20O5, is composed of a hy-droxy-naphthyl ring and a tri-meth-oxy-phenyl ring [the planes of which are inclined to one another by 21.61â (10)°] bridged by an unsaturated prop-2-en-1-one group. The mean plane of the prop-2-en-1-one group [-C(=O)-C=C-] is inclined to that of the naphthyl system and benzene rings by 3.77â (14) and 18.01â (16)°, respectively. There is an intra-molecular O-Hâ¯O hydrogen bond present forming an S(6) ring motif. In the crystal, inversion-related mol-ecules are linked by a slipped-parallel π-π inter-action [inter-centroid distance = 3.8942â (13)â Å, inter-planar distance = 3.478â (9)â Å and slippage = 1.751â Å], and stack along the [101] direction. There are no other significant inter-molecular inter-actions present.
RESUMO
In the title compound, C20H16O3, the hydro-pyran ring adopts a distorted half-chair conformation with the methine C atom and the ring O atom displaced by -0.554â (2) and 0.158â (1)â Å, respectively, from the plane of the other four atoms (r.m.s. deviation = 0.020â Å). Its mean plane (all atoms) is inclined to the naphthalene ring system at a dihedral angle of 11.67â (1)°. The dihedral angle between the napthalene ring system and the phenyl ring is 71.84â (1)°. In the crystal, no diectional inter-actions beyond van der Waals contacts could be identified.
RESUMO
In the title compound, C15H22N2O·H2O, the dihedral angle between the planes of the piperidine and benzene rings is 31.63â (1)°. The piperidine ring adopts a chair conformation. The water solvent mol-ecule is involved in inter-species O-Hâ¯O, O-Hâ¯N, N-Hâ¯O and weak C-Hâ¯O hydrogen-bonding inter-actions, giving rise to chains extending along [010].
RESUMO
The mol-ecular structure of the title compound, C21H18O4, consists of a 3,4-di-meth-oxy-phenyl ring and a naphthalene ring system linked via a prop-2-en-1-one spacer. The mol-ecule is almost planar, with a dihedral angle between the benzene ring and the naphthalene ring system of 2.68â (12)°. There is an intra-molecular O-Hâ¯O hydrogen bond involving the adjacent hy-droxy and carbonyl groups. The mol-ecule has an E conformation about the C=C bond and the carbonyl group is syn with respect to the C=C bond. In the crystal, mol-ecules are linked by bifurcated C-Hâ¯(O,O) hydrogen bonds, enclosing an R 2 (1)(6) ring motif, and by a further C-Hâ¯O hydrogen bond, forming undulating sheets extending in b- and c-axis directions. There are π-π inter-actions between the sheets, involving inversion-related naphthalene and benzene rings [inter-centroid distance = 3.7452â (17)â Å], forming a three-dimensional structure.
RESUMO
The title compound, C27H26O3, crystallized with two independent mol-ecules (A and B) in the asymmetric unit. In mol-ecule A, the plane of the central benzene ring forms dihedral angles of 75.78â (14) and 52.75â (16)° with that of the terminal benzene rings, and the dihedral angle between the planes of the terminal benzene rings is 51.49â (17)°. The corresponding values for mol-ecule B are 75.18â (14), 58.11â (16) and 47.91â (16)°, respectively. The cyclo-hexene ring adopts an envelope conformation in both mol-ecules, with the C atom to which is attached the central benzene ring as the flap. The crystal packing, is stabilized by C-Hâ¯π inter-actions.
RESUMO
In the title compound, C14H19ClN2O2·H2O, the piperdine ring adopts a chair conformation. The dihedral angle between the mean plane of the piperidine ring and that of the phenyl ring is 41.64â (1)°. In the crystal, mol-ecules are linked by O-Hâ¯N, N-Hâ¯O and C-Hâ¯O hydrogen bonds involving the water mol-ecule, forming double-stranded chains propagating along [010].
RESUMO
In the title compound, C20H20Cl2N2O2·H2O, the piperidine ring adopts a chair conformation with the two substituent benzene rings inclined to one another [dihedral angle 84.63â (9)°]. In the crystal, the components are linked by Ow-Hâ¯O, N-Hâ¯Ow (w = water) and C-Hâ¯O hydrogen bonds, generating a sheet structure lying parallel to (101).
RESUMO
In the title compound, C26H20O3, the pyran ring has a distorted half-chair conformation and its mean plane is inclined to the naphthalene ring system, to which it is fused, by 10.79â (9)°. The dihedral angles between the napthalene unit and the benzene and phenyl rings are 54.39â (9) and 52.65â (12)°, respectively, while the benzene and phenyl rings are inclined to one another by 74.80â (14)°. There is a short C-Hâ¯O contact in the chromen-1-one unit. In the crystal, mol-ecules are linked by two pairs of C-Hâ¯O hydrogen bonds, forming inversion dimers described by graph set motifs R 2 (2)(8) and R 2 (2)(10), giving rise to chains running parallel to (101). The chains are linked via C-Hâ¯π inter-actions, forming sheets lying parallel to (010).
RESUMO
In the title compound, C22H27N2O2, the piperidine ring adopts a half-chair conformation with the benzene rings inclined in a trans orientation with respect to the piperidine ring [dihedral angle between the benzene rings = 89.1â (1)°]. In the crystal, a three-centre asymmetric N-Hâ¯O/C-Hâ¯O hydrogen-bonding inter-action leads to the formation of chains extending along the a-axis direction.
RESUMO
In the title moleclue, C16H14O4, the dihedral angle between the benzene rings is 16.1â (3)°. The meth-oxy group is essentially coplanar with the benzene ring to which it is attached, with a C-O-C C torsion angle of 5.5â (9)°. In the crystal, mol-ecules are linked by O-Hâ¯O and bifurcated O-Hâ¯(O,O) hydrogen bonds, forming a three-dimensional network. The structure was refined as a two-component inversion twin.
RESUMO
In the title compound, C17H16O4, the dihedral angle between the benzene rings is 21.22â (1)° and the mean plane of the prop-2-en-1-one group makes dihedral angles of 10.60â (1) and 11.28â (1)°, respectively, with those of the hy-droxy-phenyl and eth-oxy-phenyl rings. The eth-oxy substituent forms a dihedral angle of 88.79â (2)° with the the prop-2-en-1-one group, which is found to be slightly twisted. In the crystal, phenolic O-Hâ¯O hydrogen bonds to the carbonyl O atom form a two-dimensional supra-molecular network structure lying parallel to (010).
RESUMO
In the title compound, C23H18O4, the meth-oxy-benzene ring and attached C=C grouping are disordered over two sets of sites in a 0.823â (5):0.177â (5) ratio. The dihedral angles between the central benzene ring and the pendant phenyl and meth-oxy-benzene ring (major orientation) are 51.21â (1) and 51.6â (1)°, respectively. In the crystal, inversion dimers linked by pairs of C-Hâ¯O hydrogen bonds generate R 2 (2)(28) loops.
RESUMO
In the title compound, C20H22N2O2, the piperidine ring adopts a chair conformation. The phenyl rings are inclined to one another by 80.1â (1)° and make dihedral angles of 46.1â (1) and 40.2â (1)° with the mean plane of the piperidine ring. In the crystal, pairs of N-Hâ¯O hydrogen bonds link the mol-ecules into inversion dimers. C-Hâ¯O inter-actions further link the mol-ecules, forming a three-dimensional supramolecular network.
RESUMO
In the title compound, C16H14O4, there is an intra-molecular O-Hâ¯O hydrogen bond. The benzene rings are inclined to one another by 13.89â (9)°. The prop-2-en-1-one group is twisted slightly, the O=C-Car-Car (ar = aromatic) and C=C-C=O torsion angles being -10.4â (3) and -7.4â (3)°, respectively. In the crystal, mol-ecules are linked by O-Hâ¯O hydrogen bonds, forming chains along [100]. These chains are further linked by O-Hâ¯O hydrogen bonds, forming corrugated sheets lying parallel to (010). There are C-Hâ¯π inter-actions present within the sheets.
RESUMO
In the title compound, C16H14O4, the benzene rings are inclined to one another by 4.91â (7)°. The conformation about the C=O and C=C bonds is trans and cis, respectively. In the crystal, mol-ecules are linked by O-Hâ¯O hydrogen bonds, forming inversion dimers with an R 2 (2)(14) ring motif. The dimers are linked via O-Hâ¯O and C-Hâ¯O hydrogen bonds, forming undulating two-dimensional networks lying parallel to (10-1). These networks are linked by further C-Hâ¯O hydrogen bonds, forming a three-dimensional structure.