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Acta Neurochir (Wien) ; 153(3): 609-16, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20972881

RESUMO

We describe the multidisciplinary findings in a pre-Columbian mummy head from Southern Peru (Cahuachi, Nazca civilisation, radiocarbon dating between 120 and 750 AD) of a mature male individual (40-60 years) with the first two vertebrae attached in pathological position. Accordingly, the atlanto-axial transition (C1/C2) was significantly rotated and dislocated at 38° angle associated with a bulging brownish mass that considerably reduced the spinal canal by circa 60%. Using surface microscopy, endoscopy, high-resolution multi-slice computer tomography, paleohistology and immunohistochemistry, we identified an extensive epidural hematoma of the upper cervical spinal canal-extending into the skull cavity-obviously due to a rupture of the left vertebral artery at its transition between atlas and skull base. There were no signs of fractures of the skull or vertebrae. Histological and immunohistochemical examinations clearly identified dura, brain residues and densely packed corpuscular elements that proved to represent fresh epidural hematoma. Subsequent biochemical analysis provided no evidence for pre-mortal cocaine consumption. Stable isotope analysis, however, revealed significant and repeated changes in the nutrition during his last 9 months, suggesting high mobility. Finally, the significant narrowing of the rotational atlanto-axial dislocation and the epidural hematoma probably caused compression of the spinal cord and the medulla oblongata with subsequent respiratory arrest. In conclusion, we suggest that the man died within a short period of time (probably few minutes) in an upright position with the head rotated rapidly to the right side. In paleopathologic literature, trauma to the upper cervical spine has as yet only very rarely been described, and dislocation of the vertebral bodies has not been presented.


Assuntos
Articulação Atlantoaxial/lesões , Causas de Morte , Vértebras Cervicais/lesões , Hematoma Epidural Espinal/história , Luxações Articulares/história , Múmias/história , Processo Odontoide/lesões , Compressão da Medula Espinal/história , Traumatismos da Coluna Vertebral/história , Adulto , Articulação Atlantoaxial/patologia , Vértebras Cervicais/patologia , História Antiga , Humanos , Luxações Articulares/patologia , Masculino , Pessoa de Meia-Idade , Múmias/patologia , Processo Odontoide/patologia , Paleopatologia , Peru , Traumatismos da Coluna Vertebral/patologia
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