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1.
Int J Biol Macromol ; 271(Pt 1): 132573, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38782315

RESUMO

Guided bone regeneration can play an important role in orthopedic applications. This work presents the synthesis and characterization of composite scaffolds based on polysaccharides loaded with microparticles of titanium or tantalum as novel materials proposed for composite systems with promising characteristics for guided bone regeneration. Ti/Ta composite scaffolds were synthesized using chitosan and gellan gum as organic substrates and crosslinked with oxidized dextran resulting in stable inorganic-organic composites. Physico-chemical characterization revealed a uniform distribution of metal nanoparticles within the scaffolds that showed a release of metals lower than 5 %. In vitro biological assays demonstrated that Ta composites exhibit a 2 times higher ALP activity than Ti and a higher capacity to support the full differentiation of human mesenchymal stem cells into osteoblasts. These results highlight their potential for bone regeneration applications.


Assuntos
Artroplastia de Quadril , Regeneração Óssea , Células-Tronco Mesenquimais , Tantálio , Alicerces Teciduais , Titânio , Humanos , Titânio/química , Regeneração Óssea/efeitos dos fármacos , Alicerces Teciduais/química , Tantálio/química , Células-Tronco Mesenquimais/citologia , Células-Tronco Mesenquimais/efeitos dos fármacos , Células-Tronco Mesenquimais/metabolismo , Quitosana/química , Polissacarídeos/química , Polissacarídeos/farmacologia , Diferenciação Celular/efeitos dos fármacos , Regeneração Tecidual Guiada/métodos , Osteoblastos/efeitos dos fármacos , Osteoblastos/citologia , Materiais Biocompatíveis/química , Materiais Biocompatíveis/farmacologia , Polissacarídeos Bacterianos/química , Polissacarídeos Bacterianos/farmacologia
2.
Cir Cir ; 86(1): 65-72, 2019.
Artigo em Inglês | MEDLINE | ID: mdl-30951039

RESUMO

In the area of medical education, and particularly in our country, medical residencies are the best educational programs for a graduated physicians; however, when young medical doctors begin a residence at hospitals, they hardly possess knowledge about the way medical services work as well as the processes they involve, which directly affects the fulfillment of their tasks, their process of learning and more importantly, it interferes in the services provided by the hospital. Therefore, it is imperative to immerse residents in the management of medical care and let them know that its main function is to harmoniously articulate every medical-administrative process related to patients as well as human, material and financial resources. One of the main goals is to achieve the fulfillment of the hospital's mission and vision with operational efficiency and humanism. This path will help physicians to make the best decisions, as well as achieving an adequate management of resources always remembering that quality in medical services and patient's safety are important.


En el área de la enseñanza médica, y particularmente dentro de nuestro país, las residencias médicas en hospitales son el mejor modelo para realizar un posgrado; sin embargo, cuando un médico joven inicia su residencia y arriba a un hospital, difícilmente posee los conocimientos de los servicios, tipo de pacientes y procesos que se realizan en dicho lugar, lo que repercute directamente en el cumplimiento de sus tareas, aprendizaje y, más importante, los servicios que ofrece el hospital. Por lo tanto, es imperante hacer partícipes a los médicos residentes en la gestión de la atención médica, darles a conocer que esta es la encargada de articular de forma armónica todos los procesos médico-administrativos en los que participan pacientes, recursos humanos, materiales y financieros, para alcanzar el cumplimiento de la misión y la visión hospitalaria con eficiencia operativa y sentido humano. De esta manera será posible orientarlos a realizar una correcta toma de decisiones y una gestión adecuada de los recursos, y a que su contribución en los procesos médico-administrativos brinde un servicio de calidad y seguridad para el paciente.


Assuntos
Administração Hospitalar/educação , Internato e Residência/métodos , Humanos , Internato e Residência/normas
3.
Cir Cir ; 86(1): 71-78, 2018.
Artigo em Espanhol | MEDLINE | ID: mdl-29681631

RESUMO

In the area of medical education, and particularly in our country, medical residencies are the best educational programs for a graduated physicians; however, when young medical doctors begin a residence at hospitals, they hardly poses knowledge about the way medical services work as well as the processes they involve, which directly affects the fulfillment of their tasks, their process of learning and more importantly, it interferes in the services provided by the hospital. Therefore, it is imperative to immerse residents in the management of medical care and let them know that its main function is to harmoniously articulate every medical-administrative process related to patients as well as human, material and financial resources. One of the main goals is to achieve the fulfillment of the hospital's mission and vision with operational efficiency and humanism. This path will help physicians to make the best decisions, as well as achieving an adequate management of resources always remembering that quality in medical services and patient's safety are important.


En el área de la enseñanza médica, y particularmente dentro de nuestro país, las residencias médicas en hospitales son el mejor modelo para realizar un posgrado; sin embargo, cuando un médico joven inicia su residencia y arriba a un hospital, difícilmente posee los conocimientos de los servicios, tipo de pacientes y procesos que se realizan en dicho lugar, lo que repercute directamente en el cumplimiento de sus tareas, aprendizaje y, más importante, los servicios que ofrece el hospital. Por lo tanto, es imperante hacer partícipes a los médicos residentes en la gestión de la atención médica, darles a conocer que esta es la encargada de articular de forma armónica todos los procesos médico-administrativos en los que participan pacientes, recursos humanos, materiales y financieros, para alcanzar el cumplimiento de la misión y la visión hospitalaria con eficiencia operativa y sentido humano. De esta manera será posible orientarlos a realizar una correcta toma de decisiones y una gestión adecuada de los recursos, y a que su contribución en los procesos médico-administrativos brinde un servicio de calidad y seguridad para el paciente.


Assuntos
Gerenciamento Clínico , Internato e Residência , Esgotamento Profissional , Competência Clínica , Tomada de Decisão Clínica , Administração Hospitalar , Humanos , Internato e Residência/organização & administração , Internato e Residência/normas , México , Cultura Organizacional , Desenvolvimento de Pessoal
4.
Radiol Clin North Am ; 51(4): 637-57, 2013 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-23830790

RESUMO

Multidetector computed tomography (MDCT) offers an important noninvasive imaging modality for confirmation and further characterization of primary lung and large airway neoplasms encountered in pediatric patients. Children represent a unique challenge in imaging, not only because of unique patient factors (eg, inability to follow instructions, motion, need for sedation) but because of the technical factors that must be optimized to reduce radiation dose. This article reviews an MDCT imaging algorithm, up-to-date imaging techniques, and clinical applications of MDCT for evaluating benign and malignant primary neoplasms of lung and large airway in infants and children.


Assuntos
Tomografia Computadorizada Multidetectores , Neoplasias do Sistema Respiratório/diagnóstico por imagem , Algoritmos , Tumor Carcinoide/diagnóstico por imagem , Carcinoma de Células Pequenas/diagnóstico por imagem , Criança , Hamartoma/diagnóstico por imagem , Hemangioma/diagnóstico por imagem , Humanos , Neoplasias Pulmonares/diagnóstico por imagem , Tomografia Computadorizada Multidetectores/métodos , Papiloma/diagnóstico por imagem , Neoplasias do Sistema Respiratório/patologia
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