[Results of a prospective standardized study of 30 patients with chronic neurological and cognitive disorders after tick bites]. / Enquête étiologique standardisée sur une cohorte de 30 patients atteints de troubles neurologiques et cognitifs chroniques après piqûre de tiques results of a prospective standardized study of 30 patients with chronic neurological and cognitive disorders after tick bites.

OBJECTIVE: Patients with chronic neurological disorders and cognitive impairment after tick bites are difficult to manage despite standard antibiotic therapy for Lyme disease. We wanted to correctly assess the disorders. METHODS: Thirty patients were hospitalized for a standardized evaluation of their disorders: clinical examination, biological and serological studies, cerebral MRI, CSF study, neurophysiological exams, and neuropsychological evaluation of cognitive functions. RESULTS: Clinical and biological results were non informative. We observed significant CSF abnormalities (64%), MRI Flair pictures (41%), neurophysiological exams (47%), and cognitive evaluation (100%). CONCLUSIONS: A large and standardized evaluation should be made for each patient to improve the management and probably the treatment of these complex chronic symptoms observed after tick bites.