1.
Acta Naturae
; 13(1): 4-15, 2021.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33959383
RESUMO
Super-enhancers (genome elements that activate gene transcription) are DNA regions with an elevated concentration of transcriptional complexes. These multiprotein structures contain, among other components, the cyclin-dependent kinases 8 and 19. These and other transcriptional protein kinases are regarded as novel targets for pharmacological inhibition by antitumor drug candidates.