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1.
Artigo em Russo | MEDLINE | ID: mdl-16438371

RESUMO

In the clinical trials of vaccine TEOVac in lower and reglamented doses under the conditions of remote vaccination, carried out on 11 volunteers, local reactions in the form of hyperemia, gingival edema (1 vaccinee), faucial hyperemia, enlargement of submaxillary lymph nodes (2 vaccinees) were registered in some of the vaccines; in one vaccinee systemic postvaccinal reaction of medium gravity was observed. Revaccination produced no negative effect on the hematological and biochemical characteristics of the blood, as well as on the urine characteristics. The study of the sensitizing vaccine to the antigens of the accumulation substrate (chick embryo), as well as its influence on the development of autoimmune reactions, revealed the absence of the allergic action of the preparation and its influence on autoimmune processes in the vaccines. The trial of the smallpox vaccine in tablets under the conditions of the primary immunization of adults was the topical and most promising trend in the improvement of smallpox vaccination, as the preparation TEOVac proved to be safe, in contrast to the traditional smallpox vaccine introduced by the scarification method, for both vaccines and nonimmunized persons having contacts with them.


Assuntos
Imunização Secundária/efeitos adversos , Vacina Antivariólica/efeitos adversos , Varíola/prevenção & controle , Vacinação/efeitos adversos , Administração Oral , Adulto , Edema/patologia , Feminino , Gengiva/patologia , Doenças da Gengiva/induzido quimicamente , Doenças da Gengiva/patologia , Humanos , Hiperemia/induzido quimicamente , Linfonodos , Linfadenite/induzido quimicamente , Masculino , Vacina Antivariólica/administração & dosagem , Glândula Submandibular , Comprimidos , Fatores de Tempo , Vacinas Atenuadas/administração & dosagem , Vacinas Atenuadas/efeitos adversos
2.
J Magn Reson ; 161(2): 210-4, 2003 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-12713972

RESUMO

We investigate the low temperature X-band electron paramagnetic resonance (EPR) of YBa(2)Cu(3)O(x) compounds with x congruent with 6.0 doped with Dy(3+), Tb(3+), and Nd(3). The EPR spectra of Dy(3+) and Tb(3+) have been identified. The EPR of Tb(3+) is used also to study the effect of suppression of high T(c) superconductivity by doping with Tb(3+). The EPR of Nd(3+) is probably masked by the intense resonance of Cu(2+). All experimental EPR results compare well with theoretical estimations.

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