1.
ACS Omega
; 7(43): 39061-39070, 2022 Nov 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-36340113
RESUMO
A method to obtain tetrahydroisoquinolines (THIQs) fused to tetrahydrofuran rings from aminosugar derivatives has been developed. The procedure relies on a key deprotection of benzyl ethers followed by a double-cyclization sequence, using FeCl3 as the sole reagent. This tandem reaction affords the construction of novel fused polycyclic heterocycles with total stereochemical control.