Embarazo y enfermedad cardiaca: se hace camino al andar / Pregnancy and cardiac disease: making headway

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Reversible pre-capillary pulmonary hypertension due to dasatinib.

Pulmonary arterial hypertension and secondary pleural effusion have been reported in association with long-term therapy with the multi-tyrosine kinase inhibitor dasatinib, approved for the treatment of chronic myeloid leukemia. Here, we present the case of a 50-year-old man, diagnosed with chronic myeloid leukemia in August 2003, who developed pulmonary arterial hypertension after > 4 years of treatment with dasatinib. The complete remission of pulmonary arterial hypertension following dasatinib discontinuation suggests an etiological role of the drug in its development, although the administration of sildenafil may have played a therapeutic role.

[Usefulness of the ECG in the sports screening of footballers affiliated to a regional sports federation]. / Rendimiento del estudio electrocardiográfico en el reconocimiento deportivo de futbolistas federados de una comunidad autónoma.

We report the results of a study carried out in 825 young football club members, all of whom underwent screening for hypertrophic cardiomyopathy using a 12-lead ECG. Echocardiographic assessment was performed in only those with positive ECG results, as defined by the European Society of Cardiology. Echocardiography proved necessary in 61 (7%) individuals with positive ECG findings, of whom 7 had echocardiographic findings indicative of left ventricular hypertrophy: five were in the "gray zone", 1 was judged to have athlete's heart, and one had been diagnosed with hypertrophic cardiomyopathy. In all these cases, ECG showed repolarization abnormalities, and 4 satisfied criteria for left ventricular hypertrophy.

Rendimiento del estudio electrocardiográfico en el reconocimiento deportivo de futbolistas federados de una comunidad autónoma / Usefulness of the ECG in the sports screening of footballers affiliated to a regional sports federation

Presentamos un estudio realizado sobre 825 futbolistas federados de las categorías juvenil y superiores, en el que se procede al cribado de miocardiopatía hipertrófica mediante electrocardiograma (ECG) de doce derivaciones; se practicó ecocardiograma sólo en los casos con ECG definido como positivo siguiendo los criterios de la Sociedad Europea de Cardiología (ESC). Fue preciso realizar estudio ecocardiográfico a 61 (7%) futbolistas con ECG positivo; 7 presentaron criterios ecocardiográficos de hipertrofia ventricular izquierda, 5 estaban en la «zona gris», se consideró a 1 sujeto como corazón de deportista y otro estaba diagnosticado de miocardiopatía hipertrófica. En todos, el ECG mostró alteraciones de la repolarización y en 4, criterios de crecimiento ventricular izquierdo

We report the results of a study carried out in 825 young football club members, all of whom underwent screening for hypertrophic cardiomyopathy using a 12-lead ECG. Echocardiographic assessment was performed in only those with positive ECG results, as defined by the European Society of Cardiology. Echocardiography proved necessary in 61 (7%) individuals with positive ECG findings, of whom 7 had echocardiographic findings indicative of left ventricular hypertrophy: five were in the "gray zone", 1 was judged to have athlete's heart, and one had been diagnosed with hypertrophic cardiomyopathy. In all these cases, ECG showed repolarization abnormalities, and 4 satisfied criteria for left ventricular hypertrophy

Enfermedad coronaria en jóvenes y síndrome metabólico / Coronary artery disease in young people and metabolic syndrome

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