RESUMO
We present the case of an 82-year-old woman with a history of well-differentiated adenocarcinoma of the cecum, stage pT3N1M0, treated ten years before with right hemicolectomy and adjuvant chemotherapy (Capecitabine and Bevacizumab). She developed painless obstructive jaundice of sudden onset. Computed tomography (CT) showed an ampullary nodule with secondary dilatation of the biliary and the pancreatic ducts. Subsequent duodenoscopy and endoscopic ultrasound identified the presence of multiple 3-10 mm tumor-like nodules from the first to the second duodenal knee, the largest one infiltrating the papillary area and preventing its cannulation. Biopsy revealed a moderately differentiated adenocarcinoma with cribriform, nidiform and acinar architectural patterns and positive immunohistochemistry for CK20 and CDX2, compatible with colon origin. The patient was treated with five cycles of chemotherapy (FOLFOX) with the disappearance of the duodenal nodules, although during follow-up she developed disease progression with a left adnexal metastasis with identical histological and immunohistochemical pattern.
RESUMO
No disponible
Assuntos
Humanos , Feminino , Idoso , Metástase Neoplásica/diagnóstico , Metástase Neoplásica/patologia , Neoplasias do Colo/complicações , Neoplasias do Colo/diagnóstico , Neoplasias do Colo/patologia , Neoplasias Colorretais/complicações , Neoplasias Colorretais/cirurgia , Neoplasias Colorretais , Broncoscopia/instrumentação , Broncoscopia/métodos , Broncoscopia , Pulmão/patologia , Pulmão , Neoplasias Brônquicas/complicações , Neoplasias BrônquicasRESUMO
Colorectal metastases affecting trachea or bronchi are highly unusual. Up to 26% of endotracheal/endobronchial metastases are due to colorectal cancer. Treatment and palliative management rely on a multidisciplinary team to improve their quality of life.
Assuntos
Adenocarcinoma/secundário , Neoplasias Brônquicas/secundário , Neoplasias Colorretais/patologia , Adenocarcinoma/patologia , Idoso , Neoplasias Brônquicas/patologia , Broncoscopia , Feminino , Humanos , Neoplasias Pulmonares/secundário , Prega Vocal/patologiaRESUMO
No disponible
Assuntos
Humanos , Masculino , Adulto , Pneumoperitônio/etiologia , Barotrauma/complicações , Acidentes por Quedas , Transtornos Traumáticos Cumulativos/diagnóstico , Mergulho/efeitos adversosAssuntos
Acidentes , Barotrauma/complicações , Mergulho/lesões , Pneumoperitônio/etiologia , Adulto , Barotrauma/etiologia , Humanos , MasculinoAssuntos
Humanos , Masculino , Feminino , Tumores do Estroma Gastrointestinal/complicações , Tumores do Estroma Gastrointestinal/diagnóstico , Tumores do Estroma Gastrointestinal/cirurgia , Proteínas Proto-Oncogênicas c-kit , Mesilatos/uso terapêutico , Tumores do Estroma Gastrointestinal/fisiopatologia , Tumores do Estroma Gastrointestinal , Laparoscopia/métodos , Laparoscopia , Metástase Neoplásica/diagnóstico , Metástase Neoplásica/tratamento farmacológico , Resistência a MedicamentosRESUMO
Physical exercise has been related with both beneficial effects on the gastrointestinal tract as with adverse effects on the latter. Gastrointestinal bleeding is one of these. In general, gastrointestinal bleeding is transient and mild. However, some cases caused by intestinal ischemia can sometimes be more serious due to the amount of bleeding and the presence of mucosal lesions. We present the case of a patient with abdominal pain and rectal bleeding caused by an extensive ischemic colitis due to vigorous physical exercise.
