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2.
Lik Sprava ; (10-12): 63-4, 1993.
Artigo em Russo | MEDLINE | ID: mdl-8030311

RESUMO

Ultrastructural changes of myocardium cells, neurons of sensorimotor cerebral cortex, endothelium of blood microvessels were registered by transmissive electron microscopy in mice receiving rock balm preparations per os. Both stimulating and toxic effects were observed dependently on used concentrations. This necessitates dosage to be strictly observed.


Assuntos
Coração/efeitos dos fármacos , Córtex Motor/efeitos dos fármacos , Miocárdio/ultraestrutura , Resinas Vegetais/farmacologia , Animais , Relação Dose-Resposta a Droga , Ventrículos do Coração/efeitos dos fármacos , Ventrículos do Coração/ultraestrutura , Substâncias Húmicas , Masculino , Camundongos , Microscopia Eletrônica , Minerais , Córtex Motor/ultraestrutura , Resinas Vegetais/toxicidade , Estimulação Química
4.
Radiobiologiia ; 31(2): 246-51, 1991.
Artigo em Russo | MEDLINE | ID: mdl-2034805

RESUMO

Dynamics of the conditioned behaviour of rats in a shuttle box was studied after combined exposure to Cs-gamma radiation (1 Gy, 1.32 Gy/min) and microwave radiation (2450 MHz, 1 mW/cm2, 3 h). The number of conditioned and interstimulus responses was found to decrease on day 5 after microwave + gamma irradiation and to increase on day 30 after gamma + microwave irradiation.


Assuntos
Comportamento Animal/efeitos da radiação , Condicionamento Clássico/efeitos da radiação , Micro-Ondas , Animais , Raios gama , Masculino , Memória de Curto Prazo/efeitos da radiação , Ratos , Fatores de Tempo
6.
Vestn Akad Med Nauk SSSR ; (8): 60-1, 1991.
Artigo em Russo | MEDLINE | ID: mdl-1950166

RESUMO

Literature data during 1980-1989 and own studies carried out at the Institute of Experimental Radiology, All-Union Research Center of Radiation Medicine, USSR AMS, summarized in the paper, describe three types of biological responses (increase, decrease and no response) to low-level ionizing radiation up to 100 Rem. It is shown that pathological changes in the biosystems exposed to radiation are detectable with sensitive techniques, the responses are phasic in nature and depend on the input information signal that causes energy redistribution and changes in the living system response.


Assuntos
Acidentes , Reatores Nucleares , Doses de Radiação , Efeitos da Radiação , Adulto , Criança , Humanos , Radiação Ionizante , Fatores de Tempo , Ucrânia
7.
Radiobiologiia ; 30(1): 119-21, 1990.
Artigo em Russo | MEDLINE | ID: mdl-2315452

RESUMO

The polarographic method permitted to register changes in the protein higher structure at radiation doses of the order of tenths Gy. A technique is proposed and optimum conditions found for taking measurements in mammalian serum and plasma in vitro. It is suggested that the proposed technique, having been tested on experimental animals, might be used for an indirect diagnosis of radiation affection in human beings.


Assuntos
Polarografia/métodos , Lesões Experimentais por Radiação/diagnóstico , Animais , Bovinos , Relação Dose-Resposta à Radiação , Raios gama , Lesões Experimentais por Radiação/sangue , Ratos , Albumina Sérica/análise , Albumina Sérica/efeitos da radiação , Soroalbumina Bovina/análise , Soroalbumina Bovina/efeitos da radiação
10.
Environ Health Perspect ; 81: 201-9, 1989 May.
Artigo em Inglês | MEDLINE | ID: mdl-2527152

RESUMO

During the course of a formal program of cooperation between the United States and the Soviet Union concerning the biological effects of physical factors in the environment, it was concluded that duplicate projects should be initiated with the general goal of determining the most sensitive and valid test procedures for evaluating the effects of microwave radiation on the central nervous system. This report details an initial step in this direction. Male rats of the Fischer 344 strain were exposed or sham exposed to 10 mW/cm2 continuous wave microwave radiation at 2.45 GHz for a period of 7 hr. Animals were subjected to behavioral, biochemical, or electrophysiological measurements during and/or immediately after exposure. Behavioral tests used were passive avoidance and activity in an open field. Biochemical measurements were ATPase (Na+, K+; Mg2+, Ca2+) and K+ alkaline phosphatase activities. Electrophysiological measurements consisted of EEG frequency analysis. Neither group observed a significant effect of microwave irradiation on open field activity. Both groups observed changes in variability of the data obtained using the passive avoidance procedure, but not in the same parameters. The U.S. group, but not the USSR group, found significantly less Na+,K+-ATPase activity in the microwave-exposed animals compared to the sham exposed animals. Both groups found incidences of statistically significant effects in the power spectral analysis of EEG frequency, but not at the same frequency. The failure of both groups to substantiate the results of the other reinforces our contention that such duplicate projects are important and necessary.


Assuntos
Encéfalo/efeitos da radiação , Micro-Ondas/efeitos adversos , Adenosina Trifosfatases/efeitos da radiação , Animais , Comportamento Animal/efeitos da radiação , Encéfalo/enzimologia , Eletroencefalografia , Cooperação Internacional , Masculino , Ratos , Ratos Endogâmicos F344 , U.R.S.S. , Estados Unidos
13.
Radiobiologiia ; 27(2): 264-6, 1987.
Artigo em Russo | MEDLINE | ID: mdl-3575673

RESUMO

DNA content of nondifferentiated and blast bone marrow cells was studied cytophotometrically after single exposure to SHF-radiation. It is supposed that cell adaptive reactions in blood system are responsible for phase changes in DNA quantity, the passage of cells through the mitotic cycle and their proliferative activity.


Assuntos
Medula Óssea/efeitos da radiação , DNA/efeitos da radiação , Micro-Ondas/efeitos adversos , Animais , Células da Medula Óssea , Ciclo Celular/efeitos da radiação , Citofotometria , Masculino , Mitose/efeitos da radiação , Ratos , Ratos Endogâmicos , Fatores de Tempo
15.
Radiobiologiia ; 25(5): 645-9, 1985.
Artigo em Russo | MEDLINE | ID: mdl-4070571

RESUMO

A study was made of morphological composition of blood leukocytes, phagocytic activity, glycogen and alkaline phosphatase content of neutrophils of animals exposed to microwaves of low intensity (1-500 mu W/cm2) generated continuously (2375 MHz) and by impulses (9400 MHz). The direction of the change in these indices and rate of the postirradiation recovery was shown to depend upon intensity and duration (30-120 days) of exposure. The response of albino rats and guinea pigs to the effect of microwaves was different. The effect of microwaves of the intensities under study on the mammalian organism was assessed.


Assuntos
Leucócitos/efeitos da radiação , Micro-Ondas , Fosfatase Alcalina/metabolismo , Animais , Glicogênio/metabolismo , Cobaias , Masculino , Neutrófilos/metabolismo , Neutrófilos/efeitos da radiação , Fagocitose/efeitos da radiação , Ratos
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