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1.
Artigo em Chinês | MEDLINE | ID: mdl-32306705

RESUMO

Environmental chemical pollutants are increasing, which brings various harms to human health. Epigenetics may be an important medium between exposure to environmental chemical contaminants and adverse health effects. Many environmental chemical pollutant exposures can regulate gene expression and promote disease occurrence and development through epigenetic mechanisms. This review outlines the mechanisms of epigenetics and the latest research advances in exposure and epigenetics of several environmental chemical substances (heavy metal arsenic, bisphenol A, dioctyl phthalate and benzene). To further understand and study the relationship between environmental chemical pollutant exposures and epigenetics in order to elucidate the mechanisms of disease occurrence and development.


Assuntos
Exposição Ambiental/efeitos adversos , Poluentes Ambientais/efeitos adversos , Epigênese Genética , Arsênio , Benzeno , Compostos Benzidrílicos , Metilação de DNA , Dietilexilftalato , Humanos , Fenóis
2.
J Virol Methods ; 74(1): 99-108, 1998 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-9763133

RESUMO

A new type of electropositive filter media particle was tested to adsorb bacteriophage f2 and enteric viruses from tap water. 3 x nutrient broth (pH 7.2) was used to elute the adsorbed viruses, and the eluate was reconcentrated by polyethylene glycol (Mw 6000) precipitation with a final concentration of 10% (wt./vol.). The adsorption of bacteriophage was reliable and efficient, and not affected by the pH value, temperature, turbidity and organic materials in water. This method gave a recovery of Polio 1 virus 96.0% for small-volume tap water; 88.7% for large-volume water; and gave a comparable recovery of HAV, Coxsackie B3 and Echo 7 from tap water. The concentration method need not acidify virus-containing water, add exogenous multivalent cation salts, or require expensive equipment.


Assuntos
Enterovirus/isolamento & purificação , Microbiologia da Água , Adsorção , Meios de Cultura , Humanos , Temperatura
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