RESUMO
Longer survival for orthotopic liver transplantation (OLT) patients over the last decade has focused emphasis on the metabolic complications that contribute to patient morbidity and mortality. The aim of our study was to analyze the prevalence of the metabolic syndrome (MS) and other risk factors after OLT among our patients at 1 year follow-up. From 2001 to 2008, we performed OLT in 210 patients with 62 exclusions leaving 148 patients for the study. We recorded age, gender, liver disease, smoking status, pre- and post-OLT body mass index, pre- and post-OLT arterial blood pressure, pre- and post-OLT fasting blood glucose, pre- and post-OLT high-density lipoproteins and triglycerides, family history of diabetes, hepatitis B and C virus status, immunosuppressive therapy, and corticosteroid bolus for rejection episodes. The MS was defined according to modified ATP III criteria. At month 12 after OLT, 29/148 patients (19.6%) developed the MS. The associated factors were obesity and hyperlipidemia pre-OLT, familial and personal history of diabetes as well as alcoholic cirrhosis. By multivariate analysis, pre-OLT body mass index (odds ratio, 3.7 [1.3-10.5]) and pre-OLT diabetes (odds ratio, 2.9 [1.1-7.9]) were independent risk factors.
Assuntos
Transplante de Fígado/efeitos adversos , Síndrome Metabólica/epidemiologia , Adulto , Idoso , Feminino , Rejeição de Enxerto/epidemiologia , Humanos , Masculino , Síndrome Metabólica/etiologia , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Caracteres SexuaisAssuntos
Humanos , Feminino , Pessoa de Meia-Idade , Adenocarcinoma/secundário , Neoplasias Encefálicas/secundário , Neoplasias Colorretais/patologia , Lobo Occipital/patologia , Lobo Temporal/patologia , Metástase Neoplásica/patologia , Imageamento por Ressonância Magnética/métodos , Lobo Occipital , Lobo TemporalRESUMO
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Assuntos
Idoso de 80 Anos ou mais , Idoso , Masculino , Humanos , Evolução Fatal , Colonoscopia , Pólipos do Colo , Diagnóstico Diferencial , Abdome Agudo , Linfoma não HodgkinAssuntos
Antagonistas de Androgênios/efeitos adversos , Doença Hepática Induzida por Substâncias e Drogas/etiologia , Ciproterona/efeitos adversos , Doença Aguda , Adenocarcinoma/complicações , Adenocarcinoma/tratamento farmacológico , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias da Próstata/complicações , Neoplasias da Próstata/tratamento farmacológicoRESUMO
Collagenous colitis is a newly recognized entity presenting clinically as chronic watery diarrhea and histologically by a thickened subepithelial collagenous band in colonic biopsies. We report the case of a middle aged woman affected of acute diarrhea in whom, after ruling out its main etiologies, the diagnosis of collagenous colitis was made.