Urban Trees and Hydrological Ecosystem Service: A Novel Approach to Analyzing the Relationship Between Landscape Structure and Runoff Reduction.

Urban stormwater runoff has posed significant challenges in the face of urbanization and climate change, emphasizing the importance of trees in providing runoff reduction ecosystem services (RRES). However, the sustainability of RRES can be disturbed by urban landscape modification. Understanding the impact of landscape structure on RRES is crucial to manage urban landscapes effectively to sustain supply of RRES. So, this study developed a new approach that analyzes the relationship between the landscape structural pattern and the RRES in Tabriz, Iran. The provision of RRES was estimated using the i-Tree Eco model. Landscape structure-related metrics of land use and cover (LULC) were derived using FRAGSTATS to quantify the landscape structure. Stepwise regression analysis was used to assess the relationship between landscape structure metrics and the provision of RRES. The results indicated that throughout the city, the trees prevented 196854.15 m3 of runoff annually. Regression models (p ≤ 0.05) suggested that the provision of RRES could be predicted using the measures of the related circumscribing circle metric (0.889 ≤ r2 ≤ 0.954) and the shape index (r2 = 0.983) of LULC patches. The findings also revealed that the regularity or regularity of the given LULC patches' shape could impact the patches' functions, which, in turn, affects the provision of RRES. The landscape metrics can serve as proxies to predict the capacity of trees for potential RRES using the obtained regression models. This helps to allocate suitable LULC through optimizing landscape metrics and management guidance to sustain RRES.

Exploring the role of nature-based typologies and stewardship schemes in enhancing urban green spaces: Citizen perceptions of landscape design scenarios and ecosystem services.

This research investigates the UK citizens' perceptions of the ecosystem services (ES) created using a range of Nature-Based Solutions (NBS) in urban green spaces (UGS). The longevity of the ES derived from UGS is dependent on the effective on-going maintenance of urban landscapes, therefore this paper also gathers data on direct UGS participation specifically through the lens of civic stewardship to assess the impact of such schemes upon ES. NBS typologies were created and used, in the mixed methods study, to gauge perceptions of and preferences for alternative urban landscape design. The UGS survey collected data from 345 respondents on ES and the NBS typologies. Twelve semi-structured interviews provide qualitative data on NBS typology preferences, perceptions, and understanding of ES as well as motivations behind civic engagement in UGS in the UK. Stewardship programmes were found to increase community resilience by providing additional ES. The results showed a preference for integrating complex, multifunctional UGS into the fabric of urban centres to ensure accessibility and to maximise engagement. More complex NBS typologies were perceived to provide additional ES when compared with traditional monoculture mown grass and shrub amenity planting. Mixed native planting and Tiny Forest NBS typologies were perceived as providing more provisioning, cultural, regulating, and supporting ES. Considering both UK citizens' perceptions of the ES gained from alternative NBS and stewardship schemes in UGS represents a holistic approach that can improve the design and management of NBS in cities. This study is the first to explore both concepts in the UK and suggests a holistic UGS approach to address urban challenges, including those related to Climate Change.

How might we utilise the concept of botanic gardens' in urban contexts to challenge plant blindness?

Plant blindness remains an understudied Anthropocentric concept. There is a societal naivety to the importance of plants, and lack of awareness of the human impact of plant life, which renders many 'plant blind'. This research develops a Plant Blindness (PB) scale to address plant blindness within a botanic and urban space, pursuing an investigation into the motivations and beliefs of people in terms of plant awareness, plant fascination and conservationist efforts. Interviews with specialists within botany and horticulture suggest how we might better understand and utilise the function of botanic gardens' within an urban context, using botanic spaces to further amplify societal interest in plant life, thus challenging plant blindness. Botanic gardens' document collections of living plants, researching and setting exemplar sustainable and ethical standards for the conservation and cultivation of rare and threatened plants, educating and bringing global plant conservation to the forefront of our natural world. Botanic gardens research innovation, scientific knowledge, heritage and expertise in sustaining a globally diverse range of plant species could be advantageous in the future design of urban spaces. It is through establishing active engagement between botanic spaces and urban spaces that plant blindness can be challenged, establishing a future vision for botanic gardens and botanic spaces, exploring the role botany could adopt within society.

Exploring the effects of the Covid-19 pandemic on people's relationships with gardens.

Gardens are places where science and art combine to create environments that often offer restorative and therapeutic experience to those who encounter them. During the Covid-19 pandemic, in the UK and elsewhere there has been a surge of interest in gardening. Public appreciation of gardens and other green spaces has grown and inequality of access to gardens and outdoor spaces has been extensively documented. Gardens are prevalent and of cultural significance in the UK, where their salutary properties have been documented for centuries. Yet people's relationships with gardens during the pandemic have been relatively underexplored in academia and were already under-researched prior to the pandemic's inception. This qualitative study investigates the relationships between people and gardens during the Covid-19 pandemic. Specifically, through thematic analysis based on in-depth interviews with 12 participants, it explores the effects that the pandemic had on people's relationships with gardens during an approximately 9-month period after the first national lockdown began in the UK. It places emphasis on health and wellbeing and garden design, using the concepts of agency and affordances as lenses through which to explore people's relationships with gardens. The results of this paper support others which have found people to be more supportive of nature-friendly garden design and to feel more connected with nature since the pandemic began.

Exploring the Driving Factors that Influence the Design, Function, and Use of Urban Wetlands in the United Kingdom.

This paper aimed to investigate the driving factors for the creation of urban wetlands and their functions and uses. A mixed methods approach was used, comprising an online survey for the general public and structured interviews with four urban wetland 'experts'. Quantitative data was obtained from the survey, and cross tabulation was used to analyse relationships between variables. Thematic analysis was used for the qualitative data from the interviews. It was found that one of the urban wetlands was created for flood control and to create an amenity space, whilst the driving factors for the other three urban wetlands were associated with biodiversity and habitat creation, which was also perceived as the most important function of an urban wetland from the survey participants. Three themes emerged from the thematic analysis: 'wildlife conservation interest'; 'landscape character development'; and 'urban wetland as an amenity space'. The survey found that participants perceived climate resiliency as an important function of wetlands, despite this not being a driving factor for the four wetlands in the interviews. Survey participants would be willing to invest time in visiting a non-local wetland landscape to encounter nature and contribute to their quality of life and wellbeing. The results of this research may be useful to inform the planning, design and management of urban wetlands as they evolve towards being a multi-use spaces. More education and awareness are needed about the benefits of these landscapes to wildlife, the environment and local communities. Supplementary Information: The online version contains supplementary material available at 10.1007/s13157-022-01610-1.

Adaptive school grounds design in response to COVID-19: Findings from six primary schools in South East England.

The purpose of this research is to look at how primary schools in England have adapted their outdoor spaces in the context of COVID-19 rules and guidelines to meet the needs of students returning from school closures and national lockdown of Spring/Summer 2020, how that impacted play and learning value of their grounds, and to consider how these findings might inform future school grounds design. Thus, we used a mixed-method approach that included qualitative interviews with representatives from six primary schools (three in rural and three in urban areas), quantitative desk research, and in-person site surveys. We used literature-based scoring criteria to quantify changes in the playground before and after the implementation of COVID-19 measures. The research reveals that the zoning of play areas and other aspects of the school grounds may negatively affected the value of play and learning. We also found a substantial disparity in the amount of outside space per pupil (OSPP) available across schools. Those with the lowest OSPP also had the lowest outdoor and environmental learning provision, lacking the flexibility to accommodate this alongside other requirements of staggered play breaks and PE. The amount of outdoor space that a school has available per pupil averaged at 32 m2 for urban schools and 43 m2 for rural schools. Finally, we have explored how spatial layout and design elements may have supported or inhibited schools' abilities to respond to children's needs, and how this might inform adaptive school grounds design considerations for the future.

Occurrence of abscesses during treatment with pazopanib in metastatic renal cancer: a case report.

BACKGROUND: Pazopanib is a multitarget tyrosine kinase inhibitor used in the treatment of renal cancer and soft tissue sarcoma. Its use is commonly associated with a number of side effects, such as hemorrhagic diathesis, neutropenia, leukopenia, thrombocytopenia, nausea, vomiting, abdominal pain, increased serum aspartate aminotransferase, increased serum alanine aminotransferase, decreased serum glucose, increased serum bilirubin, decreased serum phosphate and magnesium, fatigue, hypertension, diarrhea, anorexia, proteinuria, and hypothyroidism. Abscesses of metastases caused by pazopanib administration are rarely reported in the literature. CASE PRESENTATION: We report a case of abscesses of lung metastases related to pazopanib in a patient with metastatic renal cancer. The patient was a 53-year-old Caucasian man who developed abscesses of lung metastases during the first 3 months of treatment with pazopanib. The abscesses resolved after 1 month by stopping pazopanib and administering adequate antibiotic therapy. CONCLUSIONS: We conclude that abscesses of metastases could be a rare side effect occurring during treatment with pazopanib in patients with renal cancer.

Contribution of submicronic (PM1) and coarse (PM>1) particulate matter deposition to the heavy metal load of lichens transplanted along a busy road.

The aim of this study was to estimate the contribution of submicronic (PM1) and coarse (PM > 1) particulate matter deposition to the heavy metal load of lichens exposed along a busy road, based on the assumption that the accumulation of heavy metals occurs mostly as particles. We tested the hypothesis that lichens exposed inside a nylon cover with mesh size of 1 µm accumulate less heavy metals than lichens exposed without any cover. To this purpose, thalli of the lichen Evernia prunastri were transplanted for three months along a busy road of the urban area of Siena (Central Italy), with half of the samples exposed inside a nylon cover with a mesh size of 1 µm. The content of Al, As, Cd, Cr, Cu, Fe, Ni, Pb, Sb, and Zn was measured by ICP-MS before and after the exposure. The results showed that samples exposed inside the nylon cover accumulated a lower amount of most chemical elements and that Sb, along with Cd and Cu were the main traffic-related elements in the study area. Differences in element uptake were not caused by differences in sample vitality caused by the experimental procedure. Using a conversion factor it was possible to estimate element deposition rates for PM1 and PM > 1.

Modern Compact Cities: How Much Greenery Do We Need?

The modern compact city is identified as a high-density and mixed-use pattern. Its features are believed to contribute to a form of functional urban design that supports sustainability and, restresses, the importance of ecosystem services. Urban green space (UGS) plays a vital role in the design and impact on how compact cities have developed and triggered a scientific discord on the amount of greenery individuals require and to what extent contemporary approaches address the question. Research points to at least 9 m² of green space per individual with an ideal UGS value of 50 m² per capita. An examination on the perception, use, quality, accessibility and health risks of urban green and blue spaces is explored, alongside the availability of novel UGS and greenery-related approaches that investigate compact city design and planning for health and wellbeing. The amount of 'green' and relating UGS availability in cities indicates vital knowledge modern compact cities must consider.

Engineering Thermoplastics for Additive Manufacturing: A Critical Perspective with Experimental Evidence to Support Functional Applications.

BACKGROUND: Among additive manufacturing techniques, the filament-based technique involves what is referred to as fused deposition modeling (FDM). FDM materials are currently limited to a selected number of polymers. The present study focused on investigating the potential of using high-end engineering polymers in FDM. In addition, a critical review of the materials available on the market compared with those studied here was completed. METHODS: Different engineering thermoplastics, ranging from industrial grade polycarbonates to novel polyetheretherketones (PEEKs), were processed by FDM. Prior to this, for innovative filaments based on PEEK, extrusion processing was carried out. Mechanical properties (i.e., tensile and flexural) were investigated for each extruded material. An industrial-type FDM machine (Stratasys Fortus® 400 mc) was used to fully characterize the effect of printing parameters on the mechanical properties of polycarbonate. The obtained properties were compared with samples obtained by injection molding. Finally, FDM samples made of PEEK were also characterized and compared with those obtained by injection molding. RESULTS: The effect of raster to raster air gap and raster angle on tensile and flexural properties of printed PC was evidenced; the potential of PEEK filaments, as novel FDM material, was highlighted in comparison to state of the art materials. CONCLUSIONS: Comparison with injection molded parts allowed to better understand FDM potential for functional applications. The study discussed pros and cons of the different materials. Finally, the development of novel PEEK filaments achieved important results offering a novel solution to the market when high mechanical and thermal properties are required.

Highly enantioselective epoxidation catalyzed by cinchona thioureas: synthesis of functionalized terminal epoxides bearing a quaternary stereogenic center.

A brilliant debut! Cinchona thioureas have been reported for the first time as catalysts in the area of asymmetric oxidations. They efficiently promote an unprecedented highly enantioselective epoxidation of deactivated 1,1-disubstituted alkenes to terminal epoxides containing a quaternary stereogenic center (see scheme).

Hexafluorobenzene: a powerful solvent for a noncovalent stereoselective organocatalytic Michael addition reaction.

A dramatic enhancement of the diastereo- and enantioselectivity in the nitro-Michael addition reaction organocatalysed by a commercially available α,α-L-diaryl prolinol was disclosed when performing the reaction in unconventional hexafluorobenzene as a medium. DFT calculations were performed to clarify the origin of stereoselectivity and the role of C(6)F(6).

Base promoted synthesis of activated cyclopropanes bearing homologated carbonyl groups via tandem Michael addition-intramolecular enolate trapping.

A simple base promoted intramolecular Michael initiated ring closure reaction of γ-hydroxyenone derived diphenyl phosphinates with 1,3-indandione, enabled the synthesis of novel activated cyclopropanes with homologated carbonyl moiety in good yield. Promising levels of enantioselectivity are achieved when using cinchona derivatives as promoters.

Absolute configuration assignment of (3-phenyloxirane-2,2-diyl)bis(phenylmethanone) via density functional calculations of optical rotation and vibrational circular dichroism.

Density Functional Theory (DFT) calculations of optical rotation (OR) and vibrational circular dichroism (VCD) have been used to assign the absolute configuration (AC) of a recently prepared (3-phenyloxirane-2,2-diyl)bis(phenylmethanone), 3, by asymmetric epoxidation of the corresponding 2-arylidene-1,3-diketone. The experimental OR at 589.3 nm and the VCD spectrum of the (+)- and (-)-enantiomer of 3 have been measured. The conformationally-averaged OR value and VCD spectrum of (R)-3 were calculated at B3LYP/6-311G(2d,2p) level of theory. Both approaches provide the same absolute configuration of the stereogenic carbon, i.e. the AC of (+)-3 is (R)-3, thus affording a confident assignment. Only two conformational isomers of 3 have been predicted to be populated at ambient temperature. Their presence is directly observed in the VCD spectrum.

Asymmetric epoxidation of 2-arylidene-1,3-diketones: facile access to synthetically useful epoxides.

In this article the first enantioselective epoxidation reaction of acyclic and cyclic 2-arylidene-1,3-diketones is reported. Easily accessible or commercially available alpha,alpha-diaryl prolinols as the organocatalysts in the presence of tert-butyl hydroperoxide (TBHP) provide the corresponding epoxides in high to excellent yield (up to 99%) and up to 85% ee (ee >90% after crystallisation). These epoxides are pharmaceutically important building blocks and intermediates for the synthesis of densely functionalised epoxide derivatives.