[The effect of a sodium nucleinate and levamisole combination on the effectiveness of antibiotic therapy and bicillin prophylaxis of erysipelas recurrences]. / Vliianie kombinatsii nukleinata natriia i levamizola na éffektivnost' antibiotikoterapii i bitsillinoprofilaktiki retsidivov rozhi.

Two hundred and two patients with acute erysipelas and 28 patients in remission of the disease were examined. 102 patients of the main group were treated with sodium nucleinate and levamisole in addition to the routine therapy and 100 patients of the control group were subjected to the routine therapy alone. The favourable effect of the immunomodulators on the clinical picture of the disease and the immune status of the patients was shown.

[Circulating immune complexes in the pathogenesis of recurrent erysipelas]. / Tsirkuliruiushchie immunnye kompleksy v patogeneze retsidiviruiushchei rozhi.

The dynamics of circulating immune complexes (CIC) in comparison with the level of SH-groups of serum deproteinate and other characteristics of cell-mediated and humoral immunity (the reaction of the inhibition of antibodies, the levels of T-cells and their main subpopulations) was studied in 103 erysipelas patients and in 46 persons having had the disease at the acute period of this infection and at the periods between relapses. The elevated levels of CIC and SH-groups of serum deproteinate were found to be directly correlated with the inhibition index. The study showed that, as a rule, in patients with the elevated level of CIC the frequently relapsing form of erysipelas, accompanied by the formation of relative hypersuppressor-type secondary immunodeficiency and by a decrease in the functional activity of dermal macrophages, was observed.

[Possibility of increasing the efficacy of antibiotic therapy of erysipelas using combinations of methyluracil with prodigiozan]. / O vozmozhnosti povysheniia éffektivnosti antibiotikoterapii rozhi kombinatsiei metiluratsila s prodigiozanom.

Two hundred and six patients with erysipelas were examined. Of these, 100 patients were subjected to the routine therapy and 106 were additionally treated with methyluracil and prodigiosan. It was noted that the use of methyluracil and prodigiosan in the combined treatment of erysipelas promoted an increase in the efficacy of the antibiotic therapy owing to acceleration of the local inflammation regression and the favourable effect of the treatment on the cell immunity.