RESUMO
This study was performed to assess the short-term effect of sutureless scleral tunnel trabeculectomy procedure with and without topical bevacizumab. Thirty patients with Primary Open-Angle Glaucoma (POAG) were enrolled and randomly divided to two groups. Patients in the first group (15 patients) underwent sutureless trabeculectomy without topical bevacizumab and patients in the second group (15 patients) underwent sutureless trabeculectomy with 1.25 mg of topical bevacizumab. Intraocular Pressure (IOP) of both groups was measured by an expert ophthalmologist, without awareness of the patient's study group before the operation and six months post-operatively. Out of 30 patients in this study, six females (40%) and nine males (60%) underwent the sutureless trabeculectomy procedure (group A) as well as seven females (46.7%) and eight males (53.3%) underwent sutureless trabeculectomy with topical bevacizumab (group B). The mean age of the patients was not significantly different between the two groups (P = 0.91). A statistically significant difference in time variation of IOP was found between the two groups (P < 0.001). Mean IOP was 18.4 ± 4.35 mmHg in the sutureless group without bevacizumab and 11.73 ± 2.12 mmHg in the sutureless group with bevacizumab, six months post-surgically. No statistical significant differences were found in the baseline IOP between the two groups (P = 0.28). However, IOP changed significantly in group A and B from baseline to six months post-operatively (P = 0.004 and P < 0.001 respectively). According to the current findings, the sutureless trabeculectomy procedure is an effective surgical method for reduction of IOP. Addition of a single dose of 1.25 mg topical bevacizumab was more effective in reduction of IOP compared to sutureless trabeculectomy alone.
RESUMO
PURPOSE: To assess the changes in the ABCD keratoconus staging system 6 months after intracorneal ring segment implantation. METHODS: Fifty eyes of 50 patients with keratoconus who were implanted with the Keraring (Mediphacos, Belo Horizonte, Brazil) using the femtosecond laser were assessed. Preoperative and postoperative assessments included determination of distance uncorrected visual acuity and distance corrected visual acuity (DCVA), refraction, and Scheimpflug tomography with the Pentacam HR. In the ABCD keratoconus staging system, the elements A, B, C, and D stand for anterior and posterior radii of curvature in a 3.0-mm zone centered on the thinnest point (TP), corneal thickness at the TP, and DCVA, respectively. RESULTS: Keraring implantation produced significant flattening changes (preoperatively vs. postoperatively) in the anterior (6.60 ± 0.48 vs. 7.22 ± 0.57 mm, P < 0.001) and posterior (4.99 ± 0.47 vs. 5.16 ± 0.53 mm, P = 0.002) radii of curvature of the 3-mm zone centered on the corneal TP associated with a statistically significant improvement in the DCVA (0.56 ± 0.24 vs. 0.70 ± 0.22 in the decimal notation, P = 0.001) with no significant change in the corneal thickness at the TP (P = 0.285). The most changes occurred in element A of the ABCD keratoconus classification. Also, a 1-stage change was observed for element B, whereas elements C and D did not show changes in their postoperative stages after ring implantation. ABCD keratoconus staging before ring implantation was A2B3C2D1 and changed to A1B2C2D1 6 months after surgery. CONCLUSIONS: The ABCD staging system provides a more comprehensive guide that better illustrates the structural changes and visual acuity as one aspect of visual function after the implantation of the intrastromal corneal ring segments.
