Enhanced catalytic reduction of emerging contaminant by using magnetic CuFe2O4@MIL-100(Fe) in Fenton-based electrochemical processes.

Fenton-based electrochemical processes (FEPs) using newly engineered 3D photocatalyst nanocomposites have garnered significant attention owing to their ability to remove emerging contaminants. Despite the development of numerous materials, there is still a need to enhance their efficiency, stability, and recyclability to address the limitations of FEPs. This study seeks to address this issue by investigating sustainable methods to engineer novel 3D core-shell photocatalyst composites for application in FEPs. These materials can update the photo-assisted FEPs activity, and magnetism can be helpful for the easy recyclability of the catalyst. Herein, we successfully synthesized a magnetic and photoactive CuFe2O4@MIL-100(Fe) (CM) composite through sustainable methods and assessed its morphological structure and physicochemical and photocatalytic properties. The catalytic performance of CM was investigated in an undivided RuO2/air-diffusion cell to treat Cefadroxil. The results show that heterogeneous photoelectro-Fenton (HPEF) (100% in 120 min) has higher degradation efficiency than electro-Fenton (100% in 210 min) and electrooxidation (73.3% in 300 min) processes. The superior degradation efficiency of HPEF is attributed to the formation of a large amount of hydroxyl radicals indicating the excellent photocatalytic activity of the material due to the direct excitation of the Fe-O cluster, which boosts the redox reaction of Fe2+/Fe3+. Key operational parameters such as pH, catalyst concentration, current density, and CuFe2O4 proportion on MIL-100(Fe) in the composite were optimized in the HPEF process. The optimized composite exhibited good stability and easy recyclability, allowing high removal efficiency, which can be kept up after five cycles of 90 min. High degradation performance was observed using natural sunlight radiations. Additionally, possible catalytic degradation mechanisms in HPEFs were proposed based on radical quenching experiments. This study has significant potential to contribute to the development of more sustainable and effective water treatment strategies.

Study of degradation of amitriptyline antidepressant by different electrochemical advanced oxidation processes.

Amitriptyline (AMT) is the most widely used tricyclic antidepressant and is classified as a recalcitrant emergent contaminant because it has been detected in different sources of water. Its accumulation in water and soil represents a risk for different living creatures. To remove amitriptyline from wastewater, the Advanced Oxidation Processes (AOPs) stands up as an interesting option since generate highly oxidized species as hydroxyl radicals (OH) by environmentally friendly mechanism. In this work, the oxidation and mineralization of AMT solution have been comparatively studied by 3 Electrochemical AOPs (EAOPs) where the OH is produced by anodic oxidation of H2O (AO-H2O2), or by electro-Fenton (EF) or photoelectro-Fenton (PEF). PEF process with a BDD anode showed the best performance for degradation and mineralization of this drug due to the synergistic action of highly reactive physiosorbed BDD (OH), homogeneous OH and UVA radiation. This process achieved total degradation of AMT at 50 min of electrolysis and 95% of mineralization after 360 min of treatment with 0.5 mmol L-1 Fe2+ at 100 mA cm-2. Six aromatic intermediates for the drug mineralization were identified in short time of electrolysis by GC-MS, including a chloroaromatic by-product formed from the attack of active chlorine. Short-chain carboxylic acids like succinic, malic, oxalic and formic acid were quantified by ion-exclusion HPLC. Furthermore, the formation of NO3- ions was monitored. Finally, the organic intermediates identified by chromatographic techniques were used to propose the reaction sequence for the total mineralization of AMT.

[Trichodysplasia spinulosa. Report of one case]. / Tricodisplasia espinulosa asociada a síndrome mielodisplásico e inmunosupresión.

Trichodysplasia spinulosa is a rare disease that occurs in the setting of immunosuppression, associated with tolerogenic therapy used in allograft recipients or patients with hematologic malignancies. Clinically, it is characterized by a centrofacial cutaneous eruption of erythematous papules with a central keratinous spicule, often associated with variable degrees of alopecia. Histologic findings are characteristic, and electron microscopy reveals the presence of trichodysplasia spinulosa associated polyomavirus. We report a 47-year-old woman with idiopathic autoimmune pancytopenia refractory to diverse immunosuppressant regimens, with clinical and pathologic findings compatible with the disease, in whom complementary studies were required to exclude other differential diagnoses.

Tricodisplasia espinulosa asociada a síndrome mielodisplásico e inmunosupresión / Trichodysplasia spinulosa: report of one case

Trichodysplasia spinulosa is a rare disease that occurs in the setting of immunosuppression, associated with tolerogenic therapy used in allograft recipients or patients with hematologic malignancies. Clinically, it is characterized by a centrofacial cutaneous eruption of erythematous papules with a central keratinous spicule, often associated with variable degrees of alopecia. Histologic findings are characteristic, and electron microscopy reveals the presence of trichodysplasia spinulosa associated polyomavirus. We report a 47-year-old woman with idiopathic autoimmune pancytopenia refractory to diverse immunosuppressant regimens, with clinical and pathologic findings compatible with the disease, in whom complementary studies were required to exclude other differential diagnoses.

Electrochemical degradation of the antihypertensive losartan in aqueous medium by electro-oxidation with boron-doped diamond electrode.

In this work the electrochemical oxidation of losartan, an emerging pharmaceutical pollutant, was studied. Electrochemical oxidation was carried out in batch mode, in an open and undivided cell of 100cm(3) using a boron-doped diamond (BDD)/stainless steel system. With Cl(-) medium 56% of mineralization was registered, while with the trials containing SO4(2-) as supporting electrolyte a higher mineralization yield of 67% was reached, even obtaining a total removal of losartan potassium at 80mAcm(-2) and 180min of reaction time at pH 7.0. Higher losartan potassium concentrations enhanced the mineralization degree and the efficiency of the electrochemical oxidation process. During the mineralization up to 4 aromatic intermediates were identified by ultra high performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS). Moreover, short-linear carboxylic acids, like oxalic, succinic and oxamic were detected and quantified by ion-exclusion HPLC. Finally, the ability of the electrochemical oxidation process to mineralize dissolved commercial tablets containing losartan was achieved, obtaining TOC removal up to 71% under optimized conditions (10mAcm(-2), 0.05M Na2SO4, pH 7.0 and 25°C and 360min of electrolysis).

Participación y acción colectiva en los movimientos globales de ecoaldeas y permacultura / Collective participation and action in global movements for ecovillages and permaculture

Resumen En el presente artículo se analiza la participación y la acción colectiva en los movimientos globales de Ecoaldeas y Permacultura. Se presenta el marco teórico y el enfoque metodológico de la investigación doctoral "Marcos Culturales de Acción Colectiva en los Movimientos Globales de Ecoaldeas y Permacultura. Mediaciones, Comunidades y Redes en la Construcción Social del Paradigma Sostenible". Esta investigación se basa en una perspectiva psicosocial construccionista y metodológicamente integradora para el estudio de los marcos culturales sobre las que se basa la acción social transformadora. Estos resultados pretenden contribuir al debate, reflexión y análisis de las propuestas orientadas al desarrollo humano sostenible, como formas de acción que permiten la generación de respuestas a los complejos contextos de crisis socioambientales.

Abstract This paper analyzes participation and collective action in the global movements of Ecovillage and Permaculture. We present the theoretical and methodological approach of the doctoral research entitled "Collective Action Frameworks for Cultural Global Movements in Ecovillages and Permaculture. Mediations, Communities and Social Networks in Building Sustainable Paradigm". This research is based on a psychosocial perspective which integrates constructionist and methodology in order to study cultural frameworks based on transformative social action. These results seek to contribute to the discussion, reflection and analysis of proposals for sustainable human development as forms of action which will ultimately allow the generation of responses to complex socio-environmental crisis contexts.

Cáncer de próstata en menores de 50 años / Prostate cancer in people younger than 50 years old

Se reconocen las características clínicas de los pacientes con CaP menores de 50 años. Material y método: Se revisaron en forma retrospectiva los antecedentes clínicos entre julio 1994 y julio 2004. Se estudiaron las características de la pieza operatoria, la evolución quirúrgica, la sobrevida y recurrencia, incluyendo la necesidad de tratamientos complementarios. Resultados: Entre julio 1994 y julio 2004 se intervinieron 33 pacientes por CaP de 50 años o menos, se contaba con los datos necesarios para el estudio en 30. La edad promedio al momento del diagnóstico fue 46 años. El 30 por ciento de los pacientes tenía un hermano o padre con diagnóstico de CaP. El nivel de APE promedio en el momento del diagnóstico fue de 10,36 ng/ml. El estadio clínico fue T1c en el 66 por ciento, T2 en el 19 por ciento y T3 en el 9,5 por ciento. Veintinueve pacientes fueron sometidos a prostatectomía radical, confirmándose adenocarcinoma de próstata. En todos los pacientes que se realizó linfadenectomía, ésta fue negativa. El estadio patológico fue pT3 en el 39 por ciento y pT2 en el 61 por ciento. En 15 pacientes se preservó los haces neurovasculares, y el 72 por ciento de ellos preservó función eréctil. En todos los pacientes la continencia es completa. Un 69 por ciento de los pacientes operados mantienen APE indetectable hasta la fecha, sin necesidad de tratamiento complementario. Dos pacientes fueron sometidos a radioterapia complementaria por falla bioquímica. Un paciente se presentó por una adenopatía supraclavicular cuya biopsia fue compatible con un adenocarcinoma de próstata que falleció luego de hormono, radio y quimioterapia. Conclusión: Pensamos que la detección precoz de cáncer prostático es particularmente relevante en este grupo etáreo en quienes debemos emplear parámetros de APE estrictos. Esto permite identificar portadores de CaP de pronóstico favorable al ser sometidos a prostatectomía radical, logrando una baja morbilidad y una excelente calidad de vida.