Monkeypox (hMPXV Infection): A Practical Review.

Monkeypox, a neglected disease previously confined to Africa, is causing a worldwide outbreak affecting predominantly males who have sex with males, especially those who are infected with HIV. The clinical presentation during the current outbreak differs from endemic cases. Treatment with tecovirimat and other antivirals is available. Immunization may be used as preexposure and postexposure prophylaxis.

COVID-19 infection in the developing world: the Peruvian perspective.

COVID-19 infections have spread widely in Peru, causing severe societal and health impact. We describe the evolution of the epidemics, the reasons for high transmission and the way the disease is diagnosed and managed in the Andean country.

4- to 8-year complication analysis of 2 'partial collum' femoral stems in primary THA.

OBJECTIVES: Compare the clinical and radiological outcome of CFP stem with the MiniHip design in a prospective series, with special interest in intraoperative periprosthetic fracture (IPPF). METHODS: We prospectively followed 101 cases treated with the MiniHip stem (Group 1) and 89 with the CFP stem (Group 2) operated between 2010 and 2014. No significant demographic differences were observed between both groups. Median follow-up was 72 months. Average stem length was 41% shorter in the MiniHip group (p < 0.001). Radiological parameters were measured and a logistcic regression model was created to evaluate factors associated with IPPF. RESULTS: Mean mHHS improved from 54 to 95 in the MiniHip group (p < 0.001) and from 64 to 98 in the CFP group (p < 0.001). No significant differences were observed in terms of loosening, infection or instability. We observed 7 IPPFs (3.68%), 3 in group 1 and 4 in group 2. After adjusting for confounders, CFP was not associated with a greater risk of IPPF (OR 3.23; 95% CI, 0.250-42.034, p = 0.368), however, a more complex fracture pattern was observed with this stem design. Prior acetabular fractures were associated with IPPF (OR 66.85; 95% CI, 1.142-3911, p = 0.043). Compared to Dorr A femurs, type Dorr B appeared protective against IPPF (OR 0.039; 95% CI, 0.001-1.109, p = 0.058). Valgus alignment tended to increase the risk of IPPF (OR 20.59; 95% CI 0.870-487.221, p = 0.061). CONCLUSIONS: MiniHip showed similar radiological outcomes to CFP at short- to mid-term follow-up without increasing IPPFs with a shorter stem length. Given that CFP produced a more complex IPPF pattern, surgeons should be cautious with alignment of this particular design, especially in Dorr A femur.

Reemplazo total de cadera con un tallo corto no cementado tipo 2B: resultados a los 2-5 años de seguimiento / Hip replacement with a type 2B cementless short stem. Results of 2 to 5 years of follow-up

Objetivo: Determinar los resultados clínicos, la supervivencia y la incidencia de fractura periprotésica intraoperatoria con un tallo corto tipo 2B de fijación cervicometafisaria. Materiales y Métodos: Se analizaron prospectivamente los primeros 100 tallos (84 pacientes) MiniHipTM (Corin, Cirencester, Reino Unido) colocados, en forma consecutiva, por un mismo cirujano. La edad promedio fue de 47 años. La indicación para un tallo corto fue: edad <55 años (85 casos) o la participación previa en deportes de impacto en pacientes de entre 56 y 60 años (15 casos). El diagnóstico inicial fue artrosis primaria de cadera en el 82% de los casos. El seguimiento promedio fue de 42 meses. Resultados: El puntaje en la escala de Harris modificada mejoró de 55 a 96 al final del seguimiento (p = 0,02) y ningún paciente refirió dolor de muslo en el posoperatorio. La supervivencia del tallo fue del 99% (IC95% 93,1-99,8). Un caso presentó una perforación de la cortical lateral intraoperatoria, tratado con revisión con un tallo no cementado convencional. Un paciente tuvo una infección aguda, que fue tratada con desbridamiento, retención de componentes y antibióticos, con resultado favorable a los 48 meses de la cirugía. Se produjeron 3 fracturas incompletas del calcar intraoperatorias (3%). Conclusiones: Se obtuvieron resultados excelentes en esta serie de pacientes jóvenes y activos operados por un mismo cirujano con un tallo corto tipo 2B, a los 2-5 años de seguimiento, con un 1% de falla por falsa vía femoral intraoperatoria. Nivel de Evidencia: IV

Objective: We aimed to determine 2- to 5-year survivorship rate, intraoperative fractures, subsidence and thigh pain rate in a consecutive, independent, one-surgeon series of surgical patients in whom a type 2B short stem was implanted. Methods: We reviewed the first 100 type 2B consecutive femoral short stems implanted in 84 patients with a mean age of 47 years old. Indications included age younger than 55 years (85 hips), or participation in impact sports in patients aging 56 to 60 years old (15 hips). Initial diagnosis was osteoarthritis in 82% of the cases. Median follow-up was 42 months. Results: Stem survivorship rate was 99% at 2 to 5 years followed by stem revision for any aseptic reason, and 98% when infection played a part. Mean Harris Hip Score improved significantly from 55 to 96 at final follow-up (p 0.02). There was one lateral cortex perforation, and three intra-operative calcar partial fractures (3%), only one of them required cerclage wiring and delayed weight-bearing. No patient referred thigh pain at final follow-up. Only one case subsided 4 mm, but then stabilized. The risk of revision was 1% after 2 to 5 years (95%CI 93.1-99.8%). Conclusions: We obtained promising short-term results with this device in this single-surgeon, non-consecutive series -including the learning curve period- using a type 2B short stem in young active patients-, in which bone preservation is warranted. Level of Evidence: IV