RESUMO
The term nasal glioma has been used to describe a congenital benign tumor of the nasal region containing neural tissue. The nature of these lesions remains open to controversy, because of the different locations of the heterotopic neural tissue involved, the deficient development of the bony structures and the persistence or not of the structural relations with the central nervous system. More recent terms define these lesions as ectopic nervous tissue. A clinical, morphological, ultrastructural and immunohistochemical study is made of two cases of nasal glioma, one associated with agenesis of the corpus callosum. In this case, the mother had been treated with clomiphene. In such cases, morphological and immunohistochemical findings support that "nasal glioma" remain valid as a descriptive term defining a congenital benign tumor composed of heterotopic neural tissue within the nasal region and covered by skin, that may recur following incomplete surgical resection.
Assuntos
Coristoma/patologia , Glioma/patologia , Neuroglia , Doenças Nasais/patologia , Neoplasias Nasais/patologia , Anormalidades Múltiplas/patologia , Adulto , Agenesia do Corpo Caloso , Anovulação/tratamento farmacológico , Biomarcadores Tumorais/análise , Clomifeno/administração & dosagem , Clomifeno/efeitos adversos , Corpo Caloso/patologia , Diagnóstico Diferencial , Feminino , Morte Fetal/patologia , Proteína Glial Fibrilar Ácida/análise , Glioma/congênito , Humanos , Lactente , Imageamento por Ressonância Magnética , Masculino , Microscopia Eletrônica , Neoplasias Nasais/congênito , GravidezRESUMO
The authors report two cases of Prune Belly syndrome (female and male newborn) with urethral obstruction and other associated malformations: imperforate anus, vaginal septae and bicornuate uterus in the female case; unilateral anorchia and hyaline membrane disease in the male. These findings support the mechanical pathogenic theory. In the cytogenetic studies no chromosomal abnormalities were detected. Both karyotypes were normal.
Assuntos
Síndrome do Abdome em Ameixa Seca/patologia , Feminino , Humanos , Incidência , Recém-Nascido , Masculino , Síndrome do Abdome em Ameixa Seca/embriologia , Síndrome do Abdome em Ameixa Seca/epidemiologia , Síndrome do Abdome em Ameixa Seca/genéticaRESUMO
A case of "epithelioid angiomatosis" detected in a homosexual patient with positive seric HIV is presented. The skin lesions cytoplasm rich, closed y clumped together, with scanty stromal compound. Warthin-Starry staining [correction of tintions] did not show Bacillus causing "cat scratch disease". We review and analyse the features of this type of proliferation in patients infected with HIV.
