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1.
Appl Radiat Isot ; 166: 109315, 2020 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-32966949

RESUMO

Existing and active low-energy Accelerator-Based BNCT programs worldwide will be reviewed and compared. In particular, the program in Argentina will be discussed which consists of the development of an Electro-Static-Quadrupole (ESQ) Accelerator-Based treatment facility. The facility is conceived to operate with the deuteron-induced reactions 9Be(d,n)10B and 13C(d,n)14N at 1.45 MeV deuteron energy, as neutron sources. Neutron production target development status is specified. The present status of the construction of the new accelerator development laboratory and future BNCT centre is shown.

2.
Appl Radiat Isot ; 106: 18-21, 2015 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-26320739

RESUMO

In this work we provide some information on the present status of accelerator-based BNCT (AB-BNCT) worldwide and subsequently concentrate on the recent accelerator technology developments in Argentina.


Assuntos
Terapia por Captura de Nêutron de Boro/instrumentação , Argentina
3.
Appl Radiat Isot ; 88: 185-9, 2014 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-24365468

RESUMO

The activity in accelerator development for accelerator-based BNCT (AB-BNCT) both worldwide and in Argentina is described. Projects in Russia, UK, Italy, Japan, Israel, and Argentina to develop AB-BNCT around different types of accelerators are briefly presented. In particular, the present status and recent progress of the Argentine project will be reviewed. The topics will cover: intense ion sources, accelerator tubes, transport of intense beams, beam diagnostics, the (9)Be(d,n) reaction as a possible neutron source, Beam Shaping Assemblies (BSA), a treatment room, and treatment planning in realistic cases.


Assuntos
Terapia por Captura de Nêutron de Boro/instrumentação , Aceleradores de Partículas/instrumentação , Radiometria/instrumentação , Desenho de Equipamento , Análise de Falha de Equipamento , Internacionalidade , Avaliação da Tecnologia Biomédica
4.
Appl Radiat Isot ; 69(12): 1676-9, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-21421324

RESUMO

Several ion sources have been developed and an ion source test stand has been mounted for the first stage of a Tandem-Electrostatic-Quadrupole facility For Accelerator-Based Boron Neutron Capture Therapy. A first source, designed, fabricated and tested is a dual chamber, filament driven and magnetically compressed volume plasma proton ion source. A 4 mA beam has been accelerated and transported into the suppressed Faraday cup. Extensive simulations of the sources have been performed using both 2D and 3D self-consistent codes.


Assuntos
Terapia por Captura de Nêutron de Boro , Eletricidade Estática
5.
Appl Radiat Isot ; 69(12): 1672-5, 2011 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-21353577

RESUMO

We describe the present status of an ongoing project to develop a Tandem-ElectroStatic-Quadrupole (TESQ) accelerator facility for Accelerator-Based (AB)-BNCT. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the (7)Li(p,n)(7)Be reaction. The machine currently being constructed is a folded TESQ with a high-voltage terminal at 0.6 MV. We report here on the progress achieved in a number of different areas.


Assuntos
Terapia por Captura de Nêutron de Boro , Terapia por Captura de Nêutron de Boro/instrumentação , Eletricidade Estática
6.
Appl Radiat Isot ; 67(7-8 Suppl): S266-9, 2009 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-19376714

RESUMO

In this work we describe the present status of an ongoing project to develop a tandem-electrostatic-quadrupole (TESQ) accelerator facility for accelerator-based (AB) BNCT at the Atomic Energy Commission of Argentina in Buenos Aires. The project final goal is a machine capable of delivering 30 mA of 2.4 MeV protons to be used in conjunction with a neutron production target based on the (7)Li(p,n)(7)Be reaction slightly beyond its resonance at 2.25 MeV. These are the specifications needed to produce sufficiently intense and clean epithermal neutron beams, based on the (7)Li(p,n)(7)Be reaction, to perform BNCT treatment for deep-seated tumors in less than an hour. An electrostatic machine is the technologically simplest and cheapest solution for optimized AB-BNCT. The machine being designed and constructed is a folded TESQ with a high-voltage terminal at 1.2 MV intended to work in air. Such a machine is conceptually shown to be capable of transporting and accelerating a 30 mA proton beam to 2.4 MeV. The general geometric layout, its associated electrostatic fields, and the acceleration tube are simulated using a 3D finite element procedure. The design and construction of the ESQ modules is discussed and their electrostatic fields are investigated. Beam transport calculations through the accelerator are briefly mentioned. Likewise, work related to neutron production targets, strippers, beam shaping assembly and patient treatment room is briefly described.


Assuntos
Terapia por Captura de Nêutron de Boro/instrumentação , Aceleradores de Partículas , Argentina , Fenômenos Biofísicos , Neoplasias Encefálicas/radioterapia , Arquitetura de Instituições de Saúde , Humanos , Eletricidade Estática
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