RESUMO
OBJECTIVE: To determine the risk factors related to the development of stroke in patients undergoing cardiac surgery. METHODS: A historical cohort study. We included 4626 patients aged > 18 years who underwent coronary artery bypass surgery, heart valve replacement surgery alone or heart valve surgery combined with coronary artery bypass grafting between January 1996 and December 2011. The relationship between risk predictors and stroke was assessed by logistic regression model with a significance level of 0.05. RESULTS: The incidence of stroke was 3% in the overall sample. After logistic regression, the following risk predictors for stroke were found: age 50-65 years (OR=2.11 - 95% CI 1.05-4.23 - P=0.036) and age >66 years (OR=3.22 - 95% CI 1.6-6.47 - P=0.001), urgent and emergency surgery (OR=2.03 - 95% CI 1.20-3.45 - P=0.008), aortic valve disease (OR=2.32 - 95% CI 1.18-4.56 - P=0.014), history of atrial fibrillation (OR=1.88 - 95% CI 1.05-3.34 - P=0.032), peripheral artery disease (OR=1.81 - 95% CI 1.13-2.92 - P=0.014), history of cerebrovascular disease (OR=3.42 - 95% CI 2.19-5.35 - P<0.001) and cardiopulmonary bypass time > 110 minutes (OR=1.71 - 95% CI 1.16-2.53 - P=0.007). Mortality was 31.9% in the stroke group and 8.5% in the control group (OR=5.06 - 95% CI 3.5-7.33 - P<0.001). CONCLUSION: The study identified the following risk predictors for stroke after cardiac surgery: age, urgent and emergency surgery, aortic valve disease, history of atrial fibrillation, peripheral artery disease, history of cerebrovascular disease and cardiopulmonary bypass time > 110 minutes.
Assuntos
Procedimentos Cirúrgicos Cardíacos/efeitos adversos , Acidente Vascular Cerebral/etiologia , Adolescente , Adulto , Idoso , Procedimentos Cirúrgicos Cardíacos/mortalidade , Estudos de Coortes , Feminino , Mortalidade Hospitalar , Humanos , Tempo de Internação , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Complicações Pós-Operatórias , Medição de Risco , Fatores de Risco , Acidente Vascular Cerebral/mortalidade , Fatores de Tempo , Adulto JovemRESUMO
Objective: To determine the risk factors related to the development of stroke in patients undergoing cardiac surgery. Methods: A historical cohort study. We included 4626 patients aged > 18 years who underwent coronary artery bypass surgery, heart valve replacement surgery alone or heart valve surgery combined with coronary artery bypass grafting between January 1996 and December 2011. The relationship between risk predictors and stroke was assessed by logistic regression model with a significance level of 0.05. Results: The incidence of stroke was 3% in the overall sample. After logistic regression, the following risk predictors for stroke were found: age 50-65 years (OR=2.11 - 95% CI 1.05-4.23 - P=0.036) and age >66 years (OR=3.22 - 95% CI 1.6-6.47 - P=0.001), urgent and emergency surgery (OR=2.03 - 95% CI 1.20-3.45 - P=0.008), aortic valve disease (OR=2.32 - 95% CI 1.18-4.56 - P=0.014), history of atrial fibrillation (OR=1.88 - 95% CI 1.05-3.34 - P=0.032), peripheral artery disease (OR=1.81 - 95% CI 1.13-2.92 - P=0.014), history of cerebrovascular disease (OR=3.42 - 95% CI 2.19-5.35 - P<0.001) and cardiopulmonary bypass time > 110 minutes (OR=1.71 - 95% CI 1.16-2.53 - P=0.007). Mortality was 31.9% in the stroke group and 8.5% in the control group (OR=5.06 - 95% CI 3.5-7.33 - P<0.001). Conclusion: The study identified the following risk predictors for stroke after cardiac surgery: age, urgent and emergency surgery, aortic valve disease, history of atrial fibrillation, peripheral artery disease, history of cerebrovascular disease and cardiopulmonary bypass time > 110 minutes. .
OBJETIVOS: Determinar os preditores de risco relacionados ao desenvolvimento de acidente vascular cerebral em pacientes que realizaram cirurgia cardíaca. Métodos: Estudo de coorte histórico. Incluímos 4626 pacientes com idade > 18 anos submetidos à cirurgia de revascularização do miocárdio, cirurgia cardíaca valvar isolada ou cirurgia valvar associada com revascularização do miocárdio, de janeiro de 1996 e dezembro de 2011. A relação entre os preditores de risco e o acidente vascular cerebral foi avaliada por modelo de regressão logística com nível de significância de 0,05. Resultados: A incidência de acidente vascular cerebral foi 3% na amostra total. A análise multivariada identificou como preditores de risco para o acidente vascular cerebral: idade 50-65 anos (OR=2,11 - 95% IC 1,05-4,23 - P=0,036) e idade > 66 anos (OR=3,22 - 95% IC 1,6-6,47 - P=0,001), cirurgia de urgência/emergência (OR=2,03 - 95% IC 1,20-3,45 - P=0,008), valvulopatia aórtica (OR=2,32 - 95% IC 1,18-4,56 - P=0,014), fibrilação atrial (OR=1,88 - 95% IC 1,05-3,34 - P=0,032), doença arterial obstrutiva periférica (OR=1,81 - 95% IC 1,13-2,92 - P=0,014), história de doença cerebrovascular (OR=3,42 - 95% IC 2,19-5,35 - P<0,001) e tempo de circulação extracorpórea >110 minutos (OR=1,71 - 95% IC 1,16-2,53 - P=0,007). A mortalidade foi 31,9% nos pacientes que sofreram AVC e 8,5% nos sem AVC (OR=5,06 - 95% IC 3,5-7,33 - P<0,001). Conclusão: Idade, cirurgia de urgência/emergência, doença de valva aórtica, história de fibrilação atrial, doença arterial obstrutiva periférica, história de doença cerebrovascular e tempo de circulação extracorpórea > 110 minutos foram preditores independentes para o desenvolvimento de AVC i...
