Rehabilitación respiratoria en pacientes post COVID-19 con tres tratamientos; experiencia en un hospital militar peruano / Respiratory rehabilitation in post-COVID-19 patients with three treatments; experience in a Peruvian military hospital / Reabilitação respiratória em pacientes pós-COVID-19 com três tratamentos; experiência em um hospital militar peruano

La pandemia de COVID-19 ha destacado la importancia de la rehabilitación en pacientes con COVID prolongado. Objetivo: describir los efectos de tres tratamientos en un programa de rehabilitación respiratoria en pacientes post COVID-19 en un hospital militar peruano. Materiales y métodos: se llevó a cabo un estudio descriptivo y observacional. La muestra se dividió en tres grupos con diferentes tratamientos: RR+VNI+O2, Oxigenoterapia convencional y RR+CNAF+O2. Se evaluaron 348, 151 y 113 pacientes respectivamente en cada grupo. Se utilizó la Escala de Borg, mMRC, el cuestionario específico de Saint George y el genérico SF-12 para medir la percepción de falta de aire, fatiga y calidad de vida post pandemia. Resultados: tras los tratamientos, se observó un aumento significativo en la saturación de oxígeno, disminución en la frecuencia cardíaca, disnea y fatiga percibida. Conclusión: esto indica una mejora notable en la intensidad del cansancio y una significativa recuperación en la calidad de vida de los pacientes evaluados.

The COVID-19 pandemic has highlighted the importance of rehabilitation in patients with long COVID. objective: Describe the effects of three treatments in a respiratory rehabilitation program in post-COVID-19 patients in a Peruvian military hospital. Materials and methods: a descriptive and observational study was carried out. The sample was divided into three groups with different treatments: RR+NIV+O2, conventional oxygen therapy and RR+CNAF+O2. 348, 151 and 113 patients were evaluated respectively in each group. The Borg Scale, mMRC, the specific Saint George questionnaire and the generic SF-12 were used to measure the perception of shortness of breath, fatigue and post-pandemic quality of life. Results: after the treatments, a significant increase in oxygen saturation, decrease in heart rate, dyspnea and perceived fatigue was observed. Conclusion: this indicates a notable improvement in the intensity of fatigue and a significant recovery in the quality of life of the patients evaluated.

A pandemia de COVID-19 destacou a importância da reabilitação em pacientes com COVID longa. Objetivo: descrever os efeitos de três tratamentos em um programa de reabilitação respiratória em pacientes pós-COVID-19 em um hospital militar peruano. Materiais e métodos: foi realizado um estudo descritivo e observacional. A amostra foi dividida em três grupos com diferentes tratamentos: FR+VNI+O2, oxigenoterapia convencional e FR+CNAF+O2. Foram avaliados 348, 151 e 113 pacientes respectivamente em cada grupo. A Escala de Borg, mMRC, o questionário específico de Saint George e o SF-12 genérico foram utilizados para mensurar a percepção de falta de ar, fadiga e qualidade de vida pós-pandemia. Resultados: após os tratamentos foi observado aumento significativo da saturação de oxigênio, diminuição da frequência cardíaca, dispneia e fadiga percebida. Conclusão: isto indica uma melhora notável na intensidade da fadiga e uma recuperação significativa na qualidade de vida dos pacientes avaliados.

Rehabilitación Respiratoria con cánula nasal de alto flujo en pacientes con enfermedades respiratorias crónicas / Respiratory Rehabilitation with high-flow nasal cannula in patients with chronic respiratory diseases / Reabilitação Respiratória com cânula nasal de alto fluxo em doentes com doença respiratória crónica

Las enfermedades respiratorias crónicas, se incrementan a nivel mundial, destacándose EPOC, fibrosis pulmonar, bronquiectasia y sumándose la condición post COVID-19 asociadas a las vías respiratorias. Objetivo. Determinar los efectos de la rehabilitación respiratoria con cánula nasal de alto flujo en pacientes con enfermedades respiratorias crónicas. Material y método. Estudio realizado en un hospital militar peruano a una muestra constituida por 115 pacientes, quienes ingresaron a un programa de Rehabilitación Respiratoria de 12 semanas con la asistencia de la Cánula de alto flujo durante cada sesión y evaluados al inicio y al final mediante el test de pararse y sentarse en un minuto. El diseño fue pre experimental con pre y post test, corte longitudinal, de tipo aplicada. Se obtuvo la media y desviación estándar y se realizó la prueba de rangos con signo de Wilcoxon, se consideró una significancia del 95% y un valor p<0,05 como estadísticamente significativo. Resultados. La media de la edad fue de 58,30 ± 8,17; el 62,6% fue hombres y 37,4% mujeres; los pacientes con condición Post COVID-19 fueron el 71.30%, seguidos de fibrosis pulmonar con 12,17%; con 7,16±1,24 (p<0,000), en el número de repeticiones mediante pararse y sentarse durante un minuto, lo que mejoró principalmente la fatiga muscular (p<0,003). Conclusiones. Se determina como cambio, que se duplica lo mínimamente significativo mediante la prueba de pararse y sentarse durante un minuto. Además, se evidencia mejor respuesta al ejercicio, con menor disnea y fatiga muscular, por efecto de la presión positiva de la cánula de alto flujo.

Chronic respiratory diseases are increasing worldwide, with COPD, pulmonary fibrosis, bronchiectasis and post COVID-19 conditions associated with the respiratory tract standing out. Objective. To determine the effects of respiratory rehabilitation with high-flow nasal cannula in patients with chronic respiratory diseases. Method. Study carried out in a Peruvian military hospital on a sample of 115 patients, who entered a 12-week Respiratory Rehabilitation program with the assistance of the high-flow nasal cannula during each session and evaluated at the beginning and at the end by means of the test of standing up and sitting down in one minute. The design was pre-experimental with pre- and post-test, longitudinal cut, applied type. The mean and standard deviation were obtained and the Wilcoxon signed-rank test was performed, a significance of 95% and a value p<0.05 was considered statistically significant. Results. The mean age was 58.30±8.17; 62.6% were male and 37.4% female; patients with Post COVID-19 condition were 71.30%, followed by pulmonary fibrosis with 12.17%; with 7.16±1.24 (p<0.000), in the number of repetitions by standing and sitting for one minute, which mainly improved muscle fatigue (p<0.003). Conclusions. It is determined as a change, that the minimally significant is duplicated by the test of standing and sitting for one minute. In addition, a better response to exercise is evidenced, with less dyspnea and muscle fatigue, due to the effect of the positive pressure of the high flow cannula.

As doenças respiratórias crónicas estão a aumentar em todo o mundo, com destaque para a DPOC, a fibrose pulmonar, as bronquiectasias e as doenças pós-COVID-19 associadas ao trato respiratório. Objetivo. Determinar os efeitos da reabilitação respiratória com cânula nasal de alto fluxo em doentes com doenças respiratórias crónicas. Método. Estudo realizado num hospital militar peruano com uma amostra de 115 pacientes, que entraram num programa de Reabilitação Respiratória de 12 semanas com a assistência da cânula nasal de alto fluxo durante cada sessão e avaliados no início e no fim através do teste de sentar e levantar de um minuto. O delineamento foi pré-experimental com pré e pós-teste, longitudinal, do tipo aplicado. Obteve-se média e desvio padrão e realizou-se o teste de Wilcoxon signed-rank, com 95% de significância e valor de p < 0,05 foi considerado estatisticamente significativo. Resultados. A média de idade foi de 58,30±8,17; 62,6% eram do sexo masculino e 37,4% do sexo feminino; pacientes com quadro pós COVID-19 foram 71,30%, seguido de fibrose pulmonar com 12,17%; com 7,16±1,24 (p<0,000), no número de repetições em pé e sentado por um minuto, que melhorou principalmente a fadiga muscular (p<0,003). Conclusões. Determina-se como mudança, que o minimamente significativo é duplicado pelo teste de estar de pé e sentado durante um minuto. Além disso, evidencia-se uma melhor resposta ao exercício, com menos dispneia e fadiga muscular, devido ao efeito da pressão positiva da cânula de alto fluxo.

Clinical efficacy of endodontic protocols on reducing cultivable bacteria and endotoxin in infected root canal in patients submitted to head and neck radiotherapy: a randomised clinical trial.

OBJECTIVES: Assess the efficacy of biomechanical preparation using a reciprocating system followed by final irrigation protocols, then intracanal medication, on reducing endotoxins and cultivable bacteria of infected teeth in irradiated patients. MATERIALS AND METHODS: Twenty-two infected single-rooted canals in patients submitted to head and neck radiotherapy were prepared by reciprocating motion and 2.5% NaOCl. Patients were randomly divided into two groups of 11 patients before the final irrigation protocol: apical positive pressure (APP) or passive ultrasonic activation (PUA). Both groups were treated in two sessions, using Ca(OH)2 as intracanal medication for 14 days. Root canal content sampling was performed after canal access (S1), after biomechanical preparation plus the irrigation protocol (S2), and after intracanal medication (S3). Chromogenic limulus amoebocyte lysate assay measured endotoxin levels (EU/mL), and bacterial load was determined by culture techniques (CFU/mL). RESULTS: Treatment protocols reduced bacterial counts after S2 in both groups (p = 0.01). S3 differed from S1 (p = 0.01), but not from S2 (p = 0.4). Endotoxin levels were reduced in both groups after S2 (P = 0.03) and were lower in S3 than in S2, with significant differences in the APP group (p = 0.03). CONCLUSIONS: Biomechanical preparation using a reciprocating system and 2.5% NaOCl in irradiated teeth, followed by the irrigation protocol (APP or PUA), demonstrated efficacy in reducing endodontic contaminants. Ca(OH)2 as intracanal medication should be performed in irradiated patients with infected root canals. CLINICAL RELEVANCE: This clinical study demonstrated that endodontic treatment in irradiated patients is efficacious at reducing bacterial load and endotoxin levels.

Strength of scapular elevation in women with TMD and asymptomatic women - a cross-sectional study

Temporomandibular disorder (TMD) is recognized for its high prevalence, presenting characteristic signs and symptoms. Cervical spine pain is present in 70% of diagnosed TMD cases. Aim To verify if women with TMD present changes in isometric muscle strength in the scapula elevation. Methods This is an observational, cross-sectional study. Thirty-five women, aged 22.89±2.04 years, were divided into the TMD group (TMDG), diagnosed with TMD according to the DC/TMD, and control group (CG), with asymptomatic individuals. The volunteers accessed a online link by the smartphone in order to answer questions on personal data, the Fonseca Anamnestic Index (FAI), Neck Disability Index (NDI), and Masticatory preference. In all participants, evaluation of the force of the scapula elevation muscles was performed, using a load cell model MM-100 (Kratos® SP, Brazil). Data were analyzed descriptively using the maximum, mean, and standard deviation and a two-way ANCOVA test was applied for all variables. A significance level of 5% was considered. Results There were no statistically significant differences between the TMDG and CG for the maximal and mean muscle strength of scapular elevation. There were statistically significant differences in FAI (p <0.001*) between the CG and the TMDG. Conclusion Based on the results, it was not possible to confirm the hypothesis that women diagnosed with TMD present lower isometric strength during scapular elevation (right/left).

Características y correlación entre distancia recorrida y la fuerza de agarre manual en peruanos que padecieron COVID-19

RESUMEN Fundamento: el mundo aún vive un gran problema de salud pública, el Sars-Cov-2 causa la enfermedad COVID-19, que produce principalmente infecciones respiratorias, con disnea, tos, fiebre e intolerancia al ejercicio; deja una gama de deficiencias con secuelas físicas a corto y largo plazo, que afectan la condición física y la fuerza de agarre de mano. Objetivo: determinar características, así como relación entre la distancia recorrida y la fuerza de agarre manual en pacientes que padecieron COVID-19. Métodos: estudio descriptivo, correlacional, transversal, realizado en el Centro de Rehabilitación Respiratoria Privado, de Lima, entre enero y marzo del año 2021. Participaron 88 pacientes mayores de 20 años, hemódinamicamente estables, con 30 días de evolución después del alta. Fueron evaluados con la prueba de caminata de 6 minutos (C6M) y fuerza de agarre medida con dinamómetro Camry. Resultados: la edad media fue 61,7±14,5. El grupo más afectado fue el mayor de 50 años. El sexo masculino, tiempo de internamiento en Unidad de Cuidados Intensivos e índice de masa corporal fueron factores influyentes en los pacientes que padecieron COVID-19. Se evidenció relación entre la distancia recorrida y la fuerza de agarre, p<0,05, rho=-0,236. La distancia recorrida fue de 504,44±56,30 y la fuerza de agarre 27,21±5,50. Conclusiones: existe correlación entre la fuerza de agarre de mano baja y normal y la distancia recorrida en los pacientes que han padecido COVID-19.

ABSTRACT Background: The world is still experiencing a major public health problem, Sars-Cov-2 causes the disease COVID-19, which mainly produces respiratory infections, with dyspnea, cough, fever and exercise intolerance; It leaves a range of deficiencies with short and long-term physical sequelae, affecting physical fitness and hand grip strength. Objective: determine characteristics, as well as the relationship between the distance traveled and the manual grip strength in patients who suffered from COVID-19. Methods: descriptive, correlational, cross-sectional study, carried out at the Private Respiratory Rehabilitation Center, in Lima, between January and March 2021. 88 patients over 20 years of age, hemodynamically stable, with 30 days of evolution after discharge participated. They were evaluated with the 6-minute walk test (C6M) and grip strength measured with a Camry dynamometer. Results: la edad media fue 61,7±14,5. El grupo más afectado fue el mayor de 50 años. El sexo masculino, tiempo de internamiento en Unidad de Cuidados Intensivos e índice de masa corporal fueron factores influyentes en los pacientes que padecieron COVID-19. Se evidenció relación entre la distancia recorrida y la fuerza de agarre, p<0,05, rho=-0,236. La distancia recorrida fue de 504,44±56,30 y la fuerza de agarre 27,21±5,50. Conclusions: existe correlación entre la fuerza de agarre de mano baja y normal y la distancia recorrida en los pacientes que han padecido COVID-19.

New Volume-Stable Collagen Matrix and Modified Coronally Advanced Flap to Treat Multiple Gingival Recessions Associated With Partially Restored Non-Carious Cervical Lesions: A Case Report.

INTRODUCTION: Gingival recession (GR) is a prevalent problem that is related to esthetic demands and dentin hypersensitivity. Frequently, GR is associated with non-carious cervical lesion (NCCLs) forming a combined defect (CD), which requires restorative and surgical treatment. Connective tissue graft procedures allow predictable root coverage but can result in patient discomfort. CASE PRESENTATION: This first case report describes multiple GRs associated with B+ NCCL at teeth #4 and #6 of a 27-year-old patient with a thin periodontal phenotype. The aim of this report was to evaluate the 6-month outcome of a new volume-stable collagen matrix (VCMX) combined with modified coronally advanced flap (MCAF) and partial restoration to treat CDs. After 6 months, significant improvement was observed regarding CD coverage (69.05%), recession reduction (2.25 mm), gingival thickness gain (0.74 mm), and keratinized tissue width gain (0.75 mm). In addition, excellent esthetic evaluation and patient comfort were achieved by using the biomaterial. CONCLUSION: VCMX associated with MCAF and partial restoration may be an option to treat multiple recession defects plus B+ NCCLs.

La somnolencia diurna y su relación con la inteligencia emocional en estudiantes universitarios. Lima, Perú / Daytime sleepiness and its relationship with emotional intelligence in university students. Lima, Peru

RESUMEN Fundamento: El dormir adecuadamente es una necesidad fisiológica de primer orden. Cuestiones tan cotidianas como la carga académica, tareas domésticas, o el trabajo nocturno, contribuyen a que algunos se priven de las horas de sueño recomendadas, y ello trae consecuencias para la salud, el estado anímico, y la inteligencia emocional. Objetivo: describir la relación entre la somnolencia diurna y la inteligencia emocional en estudiantes universitarios. Métodos: estudio descriptivo, correlacional, con 140 alumnos del sexto al décimo ciclo de la carrera de Terapia Física y Rehabilitación, en la Universidad Norbert Wiener, Lima, Perú. Se aplicó la escala de somnolencia de Epworth para evaluar la somnolencia diurna, y la Trait Meta Mood Scale para inteligencia emocional. Mediante la prueba estadística Rho de Spearman, se evaluó la correlación entre variables. Resultados: la edad media de los estudiantes fue 25,73 ± 4,2 años, y un promedio de horas de sueño de 5,86±1,28. El valor medio de somnolencia diurna fue 9,95±3,6; esta fue ligera en la mayoría de los casos (69,65 %). La inteligencia emocional presentó un valor medio de 78,66±13,08, y fue el factor reparación el de mayor puntuación (28,36±5,63), seguido de la claridad (25,91±5,58) y la atención (24,38±5,50). Se observó una correlación negativa débil entre la somnolencia diurna y la inteligencia emocional (p= 0,058). Conclusión: la somnolencia diurna tiene consecuencias en el comportamiento de las reacciones comprendidas por la inteligencia emocional. Los estudiantes universitarios de Terapia Física y Rehabilitación analizados se caracterizan fundamentalmente por presentar somnolencia diurna ligera e inteligencia emocional adecuada.

ABSTRACT Foundation: Adequate sleep is a physiological necessity of the first order. Issues as daily as academic load, housework, or night work, contribute to some depriving themselves of recommended sleep hours, and this brings consequences for health, mood, and emotional intelligence. Objective: to describe the relationship between daytime sleepiness and emotional intelligence in university students. Methods: descriptive, correlational study, with 140 students from the sixth to the tenth cycle of the Physical Therapy and Rehabilitation degree, at Norbert Wiener University, Lima, Peru. Epworth's sleepiness scale was applied to assess daytime sleepiness, and the Trait Meta Mood Scale for emotional intelligence. By means of Spearman's Rho statistical test, the correlation between variables was evaluated. Results: the students´ average age was 25.73 ± 4.2 years, and an average time hours of sleep was 5.86 ± 1.28 hours. The mean value of daytime sleepiness was 9.95 ± 3.6; This was mild in most cases (69.65%). Emotional intelligence had an average value of 78.66 ± 13.08, and the repair factor was the highest score (28.36 ± 5.63), followed by clarity (25.91 ± 5.58) and attention (24.38 ± 5.50). A weak negative correlation was observed between daytime sleepiness and emotional intelligence (p = 0.058). Conclusion: daytime sleepiness has consequences on the behavior of reactions comprised by emotional intelligence. The analyzed University Physical Therapy and Rehabilitation students are mainly characterized by mild daytime sleepiness and adequate emotional intelligence.

Overdenture on dental remaining in oncological patients: case report / Overdenture sobre remanescente dental em paciente oncológico: relato de caso

Head and neck cancer occupy the seventh place among the most common neoplasms in the world, with an annual incidence of approximately 640,000 new cases. Radiotherapy treatment has been highlighted, because there is greater tissue preservation, possibility of regression of the disease, decreased tumor volume, prevention of possible tumor recurrences and metastases, and even total cancer cure, but patients undergoing radiotherapy are at high risk of osteoradionecrosis if they perform surgical interventions in the region, such as dental implants and dental extraction, making prosthetic rehabilitation of partially edentulous patients after treating oral cancer something complex and often omitted; although it is a crucial factor in restoring oral function. Thus, the aim of the present study was to describe the planning, treatment and follow-up of a twelve-month prosthetic approach to rehabilitate the lower arch shape and function of a partially edentulous patient undergoing head and neck radiotherapy with a full denture mucus supported and tooth retained. After twelve months of follow-up, it was possible to evidence the functional and aesthetic clinical success, with preserved occlusal pattern, soft and bone tissue around and dental roots. (AU)

O câncer de cabeça e pescoço ocupa o sétimo lugar entre as neoplasias mais comuns do mundo, com uma incidência anual de aproximadamente 640.000 novos casos. O tratamento com radioterapia tem se destacado, pois há maior preservação tecidual, possibilidade de regressão da doença, diminuição do volume tumoral, prevenção de possíveis recorrências e metástases tumorais e até cura total do câncer, mas os pacientes submetidos à radioterapia apresentam alto risco de osteorradionecrose se realizar intervenções cirúrgicas na região, como implantes dentários e extração dentária, fazendo com que a reabilitação protética, de pacientes parcialmente dentados depois de tratar o câncer bucal, algo complexo e frequentemente omitido; embora seja um fator crucial para o reestabelecimento da função oral. Assim, o objetivo do presente estudo foi descrever o planejamento, tratamento e acompanhamento de doze meses de uma abordagem protética para reabilitar forma e função do arco inferior de um paciente parcialmente desdentado, submetido a radioterapia de cabeça e pescoço, com o uso de uma prótese total mucossuportada e dente retida. Após doze meses de acompanhamento, foi possível evidenciar o sucesso clínico funcional e estético, com padrão oclusal, rebordo alveolar e remanescentes dentários preservados (AU)

Comparison of Three Anxiety Management Protocols for Extraction of Third Molars With the Use of Midazolam, Diazepam, and Nitrous Oxide: A Randomized Clinical Trial.

PURPOSE: The objective of the present study was to compare 3 sedation protocols using diazepam, midazolam, and nitrous oxide. PATIENTS AND METHODS: A total of 120 patients with an indication for extraction of third molars were selected. All 120 patients had had moderate to severe levels of anxiety according to the Corah Dental Anxiety Scale. The patients were randomly divided into 3 groups. The patients' vital signs were measured, and the results analyzed by descriptive statistical analysis and statistical tests of comparison. RESULTS: No statistically significant differences were found in the patients' heart rate. However, the differences in the systolic and diastolic blood pressure were statistically significant after 15 minutes of nitrous oxide sedation. The oximetry data showed no differences among the 3 sedation protocols. We also found no statistically significant differences in the retrograde amnesia test. The differences in anxiety from preoperatively to postoperatively were statistically significant for all techniques, demonstrating their effectiveness in anxiety control. CONCLUSIONS: All 3 preoperative sedation techniques for anxious patients undergoing extraction of third molars used in the present study were effective in controlling the anxiety, with little effect on the patients' vital signs and retrograde amnesia.

Evaluation of the impact of preoperative use of dexamethasone and cyclobenzaprine in surgical extraction of lower third molars on trismus by electromyographic analysis.

PURPOSE: The aim of this study was to evaluate the influence of cyclobenzaprine and dexamethasone on ​the electrical activity of the masticatory muscles in patients who had undergone lower third molar surgery. METHODS: Thirty bilateral impacted lower third molars with indication of extraction were randomised into three groups: the control group, the dexamethasone, and the cyclobenzaprine group. To obtain muscular electrical activity and mouth opening, an electromyographic device was used at mandibular rest and maximum voluntary contraction and compared pre- and post-operatively. RESULTS: During muscle contraction, no significant difference was observed in the electromyographic records on the non-operated side. On the operated side, there was a reduction in electrical activity for both drugs pre-operatively and immediately post-operatively compared to the control group. All pharmacological agents promoted a higher mouth opening compared to control group. CONCLUSION: The results suggest that dexamethasone and cyclobenzaprine may be useful as an adjuvant in the prevention of motor dysfunctions in third molar surgery.

Photobiomodulation for the treatment of periodontal pockets in patients with type 2 diabetes: 1-year results of a randomized clinical trial.

This study investigated the local effect of photobiomodulation (PBM) for the treatment of periodontal pockets in patients with periodontitis and type 2 diabetes. Thirty-eight periodontal pockets presenting probing depth (PD) and clinical attachment level (CAL) ≥ 5 mm were selected from 19 patients (two pockets/patient). The selected periodontal pockets were randomly assigned to receive mechanical debridement only (control group) or mechanical debridement with PBM (PBM group). Clinical measures, such as PD, CAL, bleeding on probing (BoP), and presence of supragingival biofilm (PI), were collected and compared at baseline, 3, 6, and 12 months. After 12 months, no statistically difference was observed for mean PD and mean CAL when control and PBM groups were compared. The frequency of pockets with PD 5-6 mm was significantly lower for the PBM group at 6 months when compared to the control group. Pockets with PD ≥ 7 mm changed significantly between baseline and 3, 6, and 12 months for the PBM group, while for the control group, statistical significance was only observed between baseline and 6 months. The PBM protocol used in this study did not provide significant changes for PD and CAL in periodontal pockets when compared to mechanical therapy only. However, PBM was more effective in reducing the percentage of moderate periodontal pockets at 6 months in patients with type 2 DM.

Treatment of single maxillary gingival recession associated with non-carious cervical lesion: Randomized clinical trial comparing connective tissue graft alone to graft plus partial restoration.

BACKGROUND: Gingival recession (GR) is frequently associated with non-carious cervical lesion (NCCL) forming a combined defect (CD). The aim of this study was to evaluate a new multidisciplinary protocol for CDs. METHODS: Forty patients presenting 40 Miller's Class I or II GR defects associated with B+ tooth cervical defect were randomly allocated to one of the following treatments: test group (n = 20), partial restoration (PR) of the NCCL, in which the apical border of the restoration was placed 1 mm beyond the cement-enamel junction estimation, and connective tissue graft (CTG + PR) and Control Group (n = 20), odontoplasty of the NCCL and connective tissue graft (CTG). Clinical, aesthetic and patient-centred outcomes were evaluated. RESULTS: After 12 months, CD coverage rates were 75.3% (2.5 ± 1.0 mm) for CTG + PR and 74.6% (2.4 ± 1.1 mm) for CTG (p > 0.05). The estimated complete root coverage was 60% (n = 12) for CTG + PR and 70% (n = 14) for CTG. CTG + PR resulted in significantly better dentin hypersensitivity (DH) reduction (p = 0.034). Both groups resulted in aesthetic improvements; however, the CTG + PR group showed better gingival contour results. CONCLUSIONS: CTG and CTG + PR were effective to treat CD. Use of PR resulted in better gingival margin contour and DH reduction, without effect on CD coverage by CTG. (NCT02817763).

Local adjunct effect of antimicrobial photodynamic therapy for the treatment of chronic periodontitis in type 2 diabetics: split-mouth double-blind randomized controlled clinical trial.

Diabetes has become a global epidemic. Its complications can have a significant impact on quality of life, longevity, and public health costs. The presence of diabetes might impair the prognosis of periodontal treatments due to its negative influence on wound healing. Antimicrobial photodynamic therapy (aPDT) is a local approach that can promote bacterial decontamination in periodontal pockets. The aim of this study was to investigate the local effect of adjunct aPDT to ultrasonic periodontal debridement (UPD) and compare it to UD only for the treatment of chronic periodontitis in type 2 diabetic patients. Twenty type 2 diabetic patients with moderate to severe generalized chronic periodontitis were selected. Two periodontal pockets with probing depth (PD) and clinical attachment level (CAL) ≥5 mm received UPD only (UPD group) or UPD plus adjunct aPDT (UPD + aPDT group). Periodontal clinical measures were collected and compared at baseline and 30, 90, and 180 days. After 180 days of follow-up, there were statistically significant reductions in PD from 5.75 ± 0.91 to 3.47 ± 0.97 mm in the UPD group and from 6.15 ± 1.27 to 3.71 ± 1.63 mm in the UPD + aPDT group. However, intergroup analysis did not reveal statistically significant differences in any of the evaluated clinical parameters (p > 0.05). The adjunct application of aPDT to UPD did not present additional benefits for the treatment of chronic periodontitis in type 2 diabetic patients. The ClinicalTrials.gov identifier of the present study is NCT02627534.

Comparison of two methods of dental prophylaxis: evaluation of arterial pressure and patient comfort in a clinical randomized controlled trial / Comparação entre dois métodos de profilaxia dental: avaliação da pressão arterial e conforto do paciente. Estudo clínico controlado e randomizado

Introduction: The number of hypertensive patients is increasing and prophylaxis with bicarbonate jet are widely performed in clinical practice using large amounts of this substance in a short period of time, which may lead to increased arterial pressure. In the literature there are several studies that analyze the effect of sodium bicarbonate jet on the biofilm and dental structures, but not report the effect on arterial pressure. Aim: Evaluated the change in arterial pressure before and after two procedures of dental prophylaxis, jet baking soda application and conventional prophylaxis, and patient opinion of the comfort of each system was obtained. Material and method: We selected 20 patients aged 18 to 30 in need of prophylaxis to remove biofilm. The patients were placed into three different treatment groups: sodium bicarbonate jet (G1), conventional prophylaxis (G2) and control (G3), with a one month interval between treatments. Patients were divided into groups randomly. Measurements were performed immediately before and after the procedure, 15 and 30 minutes after the end of treatment. Patient comfort was measured using a Visual Analog Scale (VAS) at the end of each treatment. Data were analyzed by analysis of variance. Result: There was a statistically significant difference in the comfort of the procedures, with G2 and G3 being better than G1. Additionally, an increase in the diastolic blood pressure was observed in sodium bicarbonate jet group evaluated just after the procedure. Conclusion: The conventional prophylaxis is more comfortable from the patient stand point and does not alter arterial pressure.

Introdução: A quantidade de pacientes hipertensivos está aumentando e, a profilaxia com jato de bicarbonato de sódio é bastante empregada na prática clínica usando grande quantidade dessa substância em um período curto de tempo que poderia aumentar a pressão arterial. Objetivo: Foi avaliado a alteração da pressão arterial antes e após os dois métodos de profilaxia dental e obtido a opinião de conforto do paciente em relação a esses métodos. Material e método: Selecionou-se 20 pacientes, na faixa etária de 18 a 30 anos, que necessitavam de profilaxia para remoção de biofilme dental e foram submetidos aos três tipos diferentes de tratamento: jato de bicarbonato de sódio (G1), profilaxia convencional (G2), e controle (G3), em intervalos de um mês entre eles. Os pacientes foram divididos de forma randomizada. As aferições realizaram-se antes da profilaxia, imediatamente ao fim do procedimento, 15 e 30 minutos após o término do tratamento. O conforto do paciente foi medido por meio de uma Escala Analógica Visual (VAS) após o final de cada tratamento. Os dados foram analisados por meio de teste de Variância. Resultado: Houve diferença estatisticamente significante quanto ao conforto dos procedimentos, sendo G2 e G3 melhores que G1. Observou-se aumento da pressão arterial diastólica no grupo jato de bicarbonato de sódio imediatamente após a profilaxia. Conclusão: A profilaxia convencional é mais confortável do ponto de vista do paciente e não altera a pressão arterial.

Terapia antibiótica como adjuvante à terapia mecânica para o tratamento de periodontite agressiva generalizada / Antibiotic therapy as adjunctive to mechanical therapy for the treatment of generalized aggressive periodontitis ­ a literature review

O objetivo deste estudo foi avaliar os protocolos de antibióticos propostos em pacientes com periodontite agressiva generalizada (PAgG). Sessões de raspagem supragengival e polimento, instrução de higiene oral e quaisquer outros procedimentos de adequação foram realizados para alcançar um índice de placa < 20%. A raspagem e alisamento radicular (RAR) ou debridamento periodontal (associado ou não à desinfecção com clorexidina), e o debridamento periodontal ultrassônico em sessão única foram adotados. A azitromicina (AZT), a doxiciclina (DOX), o metronidazol (MET), a clindamicina, e a moxifl oxacina (MOX) foram alguns dos medicamentos testados. Alguns protocolos de antimicrobianos mostraram benefícios clínicos (redução do NS e PS, com ganho do NIC). Baseado na ação contra o Aa, a associação AMX + MET parecem ser a de eleição. No entanto, efeitos adversos, como o desconforto gastrointestinal, mal-estar geral, sonolência, náusea, dor de cabeça, gosto metálico ou eventos mais severos (erupção cutânea grave) foram observados. Por outro lado, apenas 0,7% dos pacientes relataram reações adversas com o AZT, que pode ser usado por um período menor (três dias). O uso do MET em concentrações menores (250 mg) não é efetivo. A MOX (apenas um comprimido por dia, custo reduzido) tem boa biodisponibilidade, longa meia-vida, boa penetração tecidual, e excelente tolerabilidade, parecendo tão efi ciente quanto o AMX+MET, e motivando a realização de novos protocolos de tratamento. Embora a análise microbiológica tenha demonstrado que a terapia medicamentosa foi superior em reduzir e/ou suprimir a carga microbiana subgengival, há tendência de recolonização bacteriana, ressaltando a necessidade da terapia periodontal de suporte.

The aim of this study was to evaluate the antibiotic protocols proposed to treat aggressive generalized periodontitis (AgGP) patients. Supragingival scaling and root planing, oral hygiene instructions, and other aid tools were performed to reach < 20% plaque score. The root scaling and planning or periodontal debridement (associated or not to chlorhexidine), and the ultrasonic periodontal debridement (single session) were adopted. The azithromycin (AZT), doxycycline (DOX), metronidazole (MET), clindamycin, and moxifl oxacin (MOX) were some of the investigated agents. Some antimicrobial protocols demonstrated clinical benefi ts (BoP and PD reductions, as well as CAL improvements). Based on the action against Aa, the AMX + MET association seems to be the therapy of choice. However, adverse effects, such as gastrointestinal discomfort, malaise, numbness, nausea, headache, metallic taste, or more severe reactions (cutaneous rash) were observed. On the other hand, only 0.7% of patients reported unpleasant symptoms with AZT, which can be used by a shorter period (three days). The use of MET in lower concentrations (250 mg) is not effective. The MOX (1 tablet once a day, reduced cost) seems to be as effi cient as AMX + MET, motivating the generation of new treatment protocols. Although the microbiological analysis had demonstrated that the antibiotic therapy was superior in reducing and/or eliminate the subgingival bacterial load, there is a trend for microbial recolonization, which emphasizes the need for periodontal supportive therapy.

Use of ozone therapy together to low power laser in osteonecrosis induced bisphosphonates: clinical case / O uso da ozônio terapia junto ao laser de baixa potência em osteonecrose induzida por bisfosfonatos: caso clínico

Considerando a associação causal provável entre o uso de bisfosfonatos e osteonecrose da mandíbula, bem como o elevado número de prescrições e dessas drogas todos os anos, este trabalho tem como objetivo mostrar um tratamento diferente. O uso combinadode terapia de ozônio e laser na regeneração de tecidos e reparação óssea em pacientes com osteonecrose induzida por bisfosfonatos, realizada pela disciplina de Cirurgia bucomaxilofacial e Traumatologia da Universidade Estadual Paulista “Júlio de Mesquita Filho”. Paciente do sexo feminino, branca, 53 anos, depois de um câncer de mama teve uma evolução de metástases ósseas em todo o corpo, iniciou o tratamento de quimioterapia intravenosa utilizando pamidronato 90 mg mensal a partir de 2007 que tem sido utilizado até os dias atuais, devido à estabilização da doença. A paciente procurou a instituição com sintomatologia dolorosa na mandíbula e maxila, pelo exame clínico e de imagem foram diagnosticados sítios iniciais sugestivos de osteonecrose induzida por bisfosfonatos. Na tentativa de reduzir os sintomas e sinais clínicos, para impedir o avanço das lesões, recomendamos o tratamento por terapia de ozônio junto ao laser infravermelho de baixa potência, quemostrou redução satisfatória dos sítios de necrose óssea. Embora haja variações amplas e dificuldades em tratamento de osteonecrose induzida por bisfosfonatos, foi possível regressão das lesões através das terapias conjuntas aplicadas, bem como a melhoria da expectativa de vida do paciente.

Considering the probable causal association between the use of bisphosphonates and osteonecrosis of the jaw, as well as the high number of prescriptions and use these drugs every year, this paper aims to show different treatment. The combined use of ozone therapy and laser therapy in tissue regeneration and bone repair in patients with osteonecrosis induced by bisphosphonates, held by the discipline of Oral and Maxillofacial Surgery and Traumatology, Paulista State University “Júlio de Mesquita Filho”. Female patient, white, 53 years after a breast cancer had an evolution for bone metastases throughout the body, and start the chemotherapy treatment using intra-venous pamidronate 90 mg monthly from 2007 which has been used to the present day, due to disease stabilization. The patient sought the institution complaining of painful symptoms in the mandible and maxilla, and the clinical examination and CT were diagnosed initial sites suggestive of osteonecrosis induced by bisphosphonates. In seeking to reduce the symptoms and clinical signs, to prevent progress in the lesions, we recommend treatment by ozone therapy together to infrared low-power laser, which showed satisfactory reduction in bone necrosis sites. Although there are wide variations and difficulties in treatments for osteonecrosis induced by bisphosphonates, it was possible regression of the lesions through the joint processing applied, and the improvement in life expectancy of the patient.

Osteoradionecrosis: case report / Osteorradionecrose: relato de caso

Pacientes submetidos à radioterapia como parte do tratamento do câncer de cabeça e pescoço estão sujeitos a desenvolver osteorradionecrose (ORN). As exodontias têm sido implicadas como principal fator desencadeador de ORN, particularmente em região de molares inferiores. A osteorradionecrose tem sido reportada em até 20% dos pacientes irradiados submetidos à exodontia, e é reconhecida como a mais severa complicação da radioterapia em mandíbula, acarretando grande desconforto e perda na qualidade de vida do paciente. O risco de desenvolvimento de ORN é relacionado à dose, técnica e volume de tecido irradiado, e outros fatores predisponentes como: exodontia no período peri-radioterapia, local de extração, doença periodontal preexistente, trauma causado por próteses mal adaptadas, higiene oral deficiente, deficiência nutricional, uso de álcool e fumo, e doenças sistêmicas. A injúria celular e hipóxia causadas por redução do suprimento vascular, reduzem a capacidade de recuperação dos tecidos moles e do osso, predispondo-os a necrose e osteonecrose inclusive espontânea. O manejo clínico da osteorradionecrose, é complexo e dependendo do grau de acometimento pode requerer além de uso de analgésicos e antibioticoterapia a adoção de procedimentos cirúrgicos, tendo como objetivo eliminar a dor, controlar a infecção e evitar ou reduzir a progressão da lesão.O objetivo deste trabalho é relatar um caso de osteorradionecrose atendido na clínica multidisciplinar do Projeto Onco – ICT/ UNESP São José dos Campos.

Patients undergoing radiotherapy alone or as part of the treatment of head and neck cancer are likely to develop osteoradionecrosis (ORN). Dental extractions have been inferred as the main triggering factor of ORN, particularly in mandibular molars. The osteoradionecrosis has been reported in up to 20% of irradiated patients undergoing dental extraction and is recognized as the most severe complication of radiotherapy in the mandible, causing great discomfort and loss of quality of life of patients. The risk of ORN development is related to the dose, technique, and volume of irradiated tissue, and other predisposing factors such as: extraction at peri-radiotherapy period, site of extraction, pre-existing periodontal disease, general trauma, poor oral hygiene, nutritional deficiency, alcohol and smoking, and systemic diseases. The cellular injury and hypoxia caused by decreased blood supply reduce the recoverability of soft tissue and bone, predisposing them to necrosis and osteonecrosis, even spontaneous. Clinical management of osteoradionecrosis is complex and depending on the degree of involvement, it may require analgesics and antibiotics in addition to the adoption of surgical procedures, aiming to eliminate pain, control infection, and prevent orreduce the progression ofthe lesion. This paper aimed to report a case of osteoradionecrosis treated in the multidisciplinary clinic of the Onco Project - ICT/UNESP (São José dos Campos/SP, Brazil). A female patient aged 65 years with osteoradionecrosis and fistula after radiotherapy of squamous cell carcinoma in gingiva was submitted to tooth extraction, antibiotic therapy and local care with good response and flow interruption through the fistula. During the treatment, the carcinoma relapsed and the patient was referred for oncologic treatment.

Electromyographic evaluation of superficial masseter and anterior temporal muscles after using cyclobenzaprine during extraction of impacted third molars / Avaliação eletromiografica dos músculos masseter superficial e temporal anterior após uso de ciclobenzaprina na extração de terceiros molares inclusos

Objective: Avaliamos a influência do cloridrato deciclobenzaprina (Miosan,10mg/via oral/doseúnica), administrado previamente à extração de terceiros molares inferiores inclusos na atividade elétrica dos músculos masseter superficial e temporal anterior, por meio de registros eletromiográficos, na condição de repouso, contração isométrica voluntária máxima e abertura máxima da boca,nos períodos: pré cirúrgico, cirúrgico, e pós cirúrgico (7, 15 e 30 dias), e assim contribuir com a discussão do diagnóstico de disfunções do sistema estomatognático frente aos procedimentos operatórios de longa duração. Material e Métodos Foram selecionados 20 pacientes, com indicação de extração de terceiro molar inferior incluso e impactado, sem comprometimento sistêmico, com ausência de reações alérgicas aos fármacos utilizados,de ambos os sexos, provenientes da Disciplina de Cirurgia e Traumatologia Bucomaxilofacial do Instituto de Ciência e Tecnologia de São José dos Campos da Unesp. Utilizamos o eletromiógrafo modelo EMG-800C da EMG System do Brasil Ltda de quatro canais de entrada, previamente calibrado,com eletrodos ativos e ganho de amplificação de 20vezes. Além disso, foi utilizado um canal acoplado ao sistema para registro de abertura bucal (goniômetromandibular). Resultados: Observamos que a atividade elétrica dos músculos estudados é reduzida na fase inicial do procedimento cirúrgico, embora não se altere significativamente pela presença do fármaco, durante todos os períodos avaliados.O músculo masseter, na presença do fármaco,restabelece sua atividade logo após o período pósoperatório ao contrário do grupo controle que ocorre após 7 dias. Observamos um aumento ....

Objective: The influence of cyclobenzaprine hydrochloride (Miosan,10mg/orally/single dose), taken prior to the extraction of impacted mandibular third molars on the electrical activity of superficial masseter and anterior temporal muscles was evaluated through electromyographic recordings aiming at contributing to the discussion of the diagnosis of stomatognathic dysfunctions in relation to long lasting operative procedures. Material and Methods: Twenty patients referred for the extraction of impacted and embedded mandibular third molars at the Discipline of Oral and maxillofacial Surgery and Traumatology (Institute of Science and Technology of São José dos Campos/Unesp), without systemic disease and allergic reactions to the drugs used, both sexes were selected. An electromyographer model EMG-800C (EMG System do Brasil Ltd.), with four input channels, previously calibrated with active electrodes and 20-fold amplification gain was used together with a channel linked to the system to record the mouth opening (mandibular goniometer). The following conditions were assessed: rest, maximum voluntary isometric contraction, and maximum mouth opening, at the following periods: presurgical, surgical, and post-surgical (7, 15, and 30days). Results: The electrical activity of the studied muscles was reduced at the beginning of the surgical procedure, but it did not significantly alter by the administration of the drug at all evaluated periods.The masseter muscle, after the drug administration, reestablished its activity just after the postoperative period, unlikely the control group, whichre established the activity after 7 days ....