1.
Chem Asian J
; 14(6): 859-863, 2019 Mar 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30632287
RESUMO
A fluorescent dye was decorated with water-soluble pyridinium groups in order to be applied in the detection of cyclodextrins or DNA. The dye displays an enhancement of its emission intensity when the internal rotations are restricted due to the formation of an inclusion complex with cyclodextrins or upon interaction with DNA. In vivo, the fluorescent probe can stain protein aggregates with a selectivity comparable to the widely used Proteostat®.